| Full name: ubiquilin 3 | Alias Symbol: TUP-1 | ||
| Type: protein-coding gene | Cytoband: 11p15.4 | ||
| Entrez ID: 50613 | HGNC ID: HGNC:12510 | Ensembl Gene: ENSG00000175520 | OMIM ID: 605473 |
| Drug and gene relationship at DGIdb | |||
Expression of UBQLN3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UBQLN3 | 50613 | 220422_at | -0.0182 | 0.9518 | |
| GSE20347 | UBQLN3 | 50613 | 220422_at | -0.0644 | 0.3262 | |
| GSE23400 | UBQLN3 | 50613 | 220422_at | -0.1100 | 0.0044 | |
| GSE26886 | UBQLN3 | 50613 | 220422_at | -0.1576 | 0.2412 | |
| GSE29001 | UBQLN3 | 50613 | 220422_at | -0.1827 | 0.2898 | |
| GSE38129 | UBQLN3 | 50613 | 220422_at | -0.1248 | 0.0314 | |
| GSE45670 | UBQLN3 | 50613 | 220422_at | 0.1663 | 0.0256 | |
| GSE53622 | UBQLN3 | 50613 | 138171 | -0.1643 | 0.0861 | |
| GSE53624 | UBQLN3 | 50613 | 138171 | -0.0366 | 0.6863 | |
| GSE63941 | UBQLN3 | 50613 | 220422_at | 0.0836 | 0.5697 | |
| GSE77861 | UBQLN3 | 50613 | 220422_at | 0.0292 | 0.6898 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by UBQLN3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UBQLN3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UBQLN3 | 50613 | 1 | 11 | 18 | |
| GSE20123 | UBQLN3 | 50613 | 1 | 11 | 18 | |
| GSE43470 | UBQLN3 | 50613 | 1 | 8 | 34 | |
| GSE46452 | UBQLN3 | 50613 | 7 | 8 | 44 | |
| GSE47630 | UBQLN3 | 50613 | 3 | 13 | 24 | |
| GSE54993 | UBQLN3 | 50613 | 3 | 1 | 66 | |
| GSE54994 | UBQLN3 | 50613 | 2 | 12 | 39 | |
| GSE60625 | UBQLN3 | 50613 | 0 | 0 | 11 | |
| GSE74703 | UBQLN3 | 50613 | 1 | 6 | 29 | |
| GSE74704 | UBQLN3 | 50613 | 0 | 8 | 12 | |
| TCGA | UBQLN3 | 50613 | 7 | 39 | 50 |
Total number of gains: 26; Total number of losses: 117; Total Number of normals: 345.
Somatic mutations of UBQLN3:
Generating mutation plots.
Highly correlated genes for UBQLN3:
Showing top 20/870 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UBQLN3 | GREB1L | 0.722773 | 4 | 0 | 4 |
| UBQLN3 | UMOD | 0.716387 | 5 | 0 | 5 |
| UBQLN3 | SLC5A4 | 0.715044 | 4 | 0 | 4 |
| UBQLN3 | FEV | 0.710811 | 4 | 0 | 4 |
| UBQLN3 | GPR31 | 0.705646 | 5 | 0 | 5 |
| UBQLN3 | CRYAA | 0.699317 | 3 | 0 | 3 |
| UBQLN3 | CEACAM3 | 0.697077 | 6 | 0 | 6 |
| UBQLN3 | ATP2B3 | 0.694938 | 3 | 0 | 3 |
| UBQLN3 | CKM | 0.692176 | 3 | 0 | 3 |
| UBQLN3 | SLC2A5 | 0.692018 | 3 | 0 | 3 |
| UBQLN3 | SOAT2 | 0.685951 | 4 | 0 | 3 |
| UBQLN3 | KHDRBS2 | 0.684482 | 4 | 0 | 4 |
| UBQLN3 | CPS1-IT1 | 0.682568 | 3 | 0 | 3 |
| UBQLN3 | KCNB2 | 0.682403 | 6 | 0 | 5 |
| UBQLN3 | TTLL10 | 0.681638 | 3 | 0 | 3 |
| UBQLN3 | EPB42 | 0.681082 | 5 | 0 | 5 |
| UBQLN3 | GRIP2 | 0.678818 | 6 | 0 | 6 |
| UBQLN3 | ADAMTS12 | 0.676558 | 4 | 0 | 4 |
| UBQLN3 | ASCL3 | 0.675997 | 6 | 0 | 6 |
| UBQLN3 | OR1A2 | 0.675707 | 4 | 0 | 4 |
For details and further investigation, click here
