| Full name: pregnancy specific beta-1-glycoprotein 4 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 19q13.31 | ||
| Entrez ID: 5672 | HGNC ID: HGNC:9521 | Ensembl Gene: ENSG00000243137 | OMIM ID: 176393 |
| Drug and gene relationship at DGIdb | |||
Expression of PSG4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PSG4 | 5672 | 208191_x_at | -0.2823 | 0.2334 | |
| GSE20347 | PSG4 | 5672 | 208191_x_at | -0.0794 | 0.3810 | |
| GSE23400 | PSG4 | 5672 | 208191_x_at | -0.2483 | 0.0000 | |
| GSE26886 | PSG4 | 5672 | 208191_x_at | 0.0350 | 0.9150 | |
| GSE29001 | PSG4 | 5672 | 208191_x_at | -0.2898 | 0.0628 | |
| GSE38129 | PSG4 | 5672 | 208191_x_at | -0.1966 | 0.0282 | |
| GSE45670 | PSG4 | 5672 | 208191_x_at | 0.1226 | 0.4919 | |
| GSE53622 | PSG4 | 5672 | 38824 | 0.0480 | 0.8864 | |
| GSE53624 | PSG4 | 5672 | 38824 | 0.0443 | 0.8709 | |
| GSE63941 | PSG4 | 5672 | 208191_x_at | 0.1300 | 0.8068 | |
| GSE77861 | PSG4 | 5672 | 208191_x_at | 0.0392 | 0.9108 | |
| TCGA | PSG4 | 5672 | RNAseq | 2.0323 | 0.0635 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PSG4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PSG4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PSG4 | 5672 | 6 | 5 | 19 | |
| GSE20123 | PSG4 | 5672 | 5 | 4 | 21 | |
| GSE43470 | PSG4 | 5672 | 4 | 11 | 28 | |
| GSE46452 | PSG4 | 5672 | 45 | 1 | 13 | |
| GSE47630 | PSG4 | 5672 | 8 | 6 | 26 | |
| GSE54993 | PSG4 | 5672 | 17 | 4 | 49 | |
| GSE54994 | PSG4 | 5672 | 7 | 12 | 34 | |
| GSE60625 | PSG4 | 5672 | 9 | 0 | 2 | |
| GSE74703 | PSG4 | 5672 | 4 | 7 | 25 | |
| GSE74704 | PSG4 | 5672 | 4 | 2 | 14 | |
| TCGA | PSG4 | 5672 | 14 | 15 | 67 |
Total number of gains: 123; Total number of losses: 67; Total Number of normals: 298.
Somatic mutations of PSG4:
Generating mutation plots.
Highly correlated genes for PSG4:
Showing top 20/635 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PSG4 | PSG7 | 0.73221 | 9 | 0 | 9 |
| PSG4 | PSG1 | 0.71711 | 11 | 0 | 10 |
| PSG4 | SPX | 0.709325 | 3 | 0 | 3 |
| PSG4 | CCKBR | 0.701259 | 3 | 0 | 3 |
| PSG4 | APOA1 | 0.688897 | 4 | 0 | 4 |
| PSG4 | SLC28A2 | 0.686626 | 5 | 0 | 4 |
| PSG4 | GK2 | 0.68528 | 3 | 0 | 3 |
| PSG4 | CNR2 | 0.674237 | 5 | 0 | 5 |
| PSG4 | CEACAM3 | 0.667235 | 4 | 0 | 4 |
| PSG4 | PF4 | 0.664607 | 4 | 0 | 4 |
| PSG4 | PRPH2 | 0.662192 | 5 | 0 | 4 |
| PSG4 | UMOD | 0.65865 | 5 | 0 | 3 |
| PSG4 | CCDC7 | 0.658638 | 4 | 0 | 4 |
| PSG4 | MIP | 0.657309 | 3 | 0 | 3 |
| PSG4 | DCX | 0.656237 | 3 | 0 | 3 |
| PSG4 | P2RX6 | 0.654179 | 5 | 0 | 4 |
| PSG4 | BRINP2 | 0.650273 | 5 | 0 | 5 |
| PSG4 | PRDM11 | 0.646922 | 4 | 0 | 3 |
| PSG4 | CYP2A6 | 0.64575 | 6 | 0 | 4 |
| PSG4 | XPNPEP2 | 0.645613 | 4 | 0 | 4 |
For details and further investigation, click here
