| Full name: solute carrier family 2 member 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 3q26.2 | ||
| Entrez ID: 6514 | HGNC ID: HGNC:11006 | Ensembl Gene: ENSG00000163581 | OMIM ID: 138160 |
| Drug and gene relationship at DGIdb | |||
SLC2A2 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04917 | Prolactin signaling pathway | |
| hsa04930 | Type II diabetes mellitus | |
| hsa04950 | Maturity onset diabetes of the young | |
| hsa04973 | Carbohydrate digestion and absorption |
Expression of SLC2A2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC2A2 | 6514 | 206535_at | -0.0211 | 0.9371 | |
| GSE20347 | SLC2A2 | 6514 | 206535_at | -0.0302 | 0.5687 | |
| GSE23400 | SLC2A2 | 6514 | 206535_at | -0.0694 | 0.0010 | |
| GSE26886 | SLC2A2 | 6514 | 206535_at | -0.1180 | 0.1778 | |
| GSE29001 | SLC2A2 | 6514 | 206535_at | -0.0687 | 0.5359 | |
| GSE38129 | SLC2A2 | 6514 | 206535_at | -0.0944 | 0.0494 | |
| GSE45670 | SLC2A2 | 6514 | 206535_at | 0.0320 | 0.7694 | |
| GSE53622 | SLC2A2 | 6514 | 19622 | 0.4343 | 0.0032 | |
| GSE53624 | SLC2A2 | 6514 | 19622 | 0.0387 | 0.7551 | |
| GSE63941 | SLC2A2 | 6514 | 206535_at | 0.0838 | 0.6575 | |
| GSE77861 | SLC2A2 | 6514 | 206535_at | -0.0733 | 0.2750 | |
| TCGA | SLC2A2 | 6514 | RNAseq | 1.3179 | 0.4594 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SLC2A2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC2A2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC2A2 | 6514 | 24 | 0 | 6 | |
| GSE20123 | SLC2A2 | 6514 | 24 | 0 | 6 | |
| GSE43470 | SLC2A2 | 6514 | 24 | 0 | 19 | |
| GSE46452 | SLC2A2 | 6514 | 19 | 1 | 39 | |
| GSE47630 | SLC2A2 | 6514 | 27 | 2 | 11 | |
| GSE54993 | SLC2A2 | 6514 | 1 | 15 | 54 | |
| GSE54994 | SLC2A2 | 6514 | 41 | 0 | 12 | |
| GSE60625 | SLC2A2 | 6514 | 0 | 6 | 5 | |
| GSE74703 | SLC2A2 | 6514 | 20 | 0 | 16 | |
| GSE74704 | SLC2A2 | 6514 | 16 | 0 | 4 | |
| TCGA | SLC2A2 | 6514 | 80 | 0 | 16 |
Total number of gains: 276; Total number of losses: 24; Total Number of normals: 188.
Somatic mutations of SLC2A2:
Generating mutation plots.
Highly correlated genes for SLC2A2:
Showing top 20/382 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC2A2 | SLC6A5 | 0.745789 | 3 | 0 | 3 |
| SLC2A2 | GPR17 | 0.732863 | 3 | 0 | 3 |
| SLC2A2 | DRD5 | 0.72087 | 3 | 0 | 3 |
| SLC2A2 | INSL5 | 0.717104 | 3 | 0 | 3 |
| SLC2A2 | GREB1L | 0.701862 | 3 | 0 | 3 |
| SLC2A2 | HUNK | 0.686453 | 3 | 0 | 3 |
| SLC2A2 | SLC13A3 | 0.665468 | 3 | 0 | 3 |
| SLC2A2 | IL18BP | 0.658249 | 3 | 0 | 3 |
| SLC2A2 | GYPA | 0.655828 | 3 | 0 | 3 |
| SLC2A2 | OR2W1 | 0.648679 | 4 | 0 | 4 |
| SLC2A2 | SLC5A4 | 0.647713 | 4 | 0 | 3 |
| SLC2A2 | ADAMTS12 | 0.644667 | 3 | 0 | 3 |
| SLC2A2 | HAPLN1 | 0.643823 | 3 | 0 | 3 |
| SLC2A2 | KLF15 | 0.643312 | 3 | 0 | 3 |
| SLC2A2 | IFNA5 | 0.642991 | 3 | 0 | 3 |
| SLC2A2 | CER1 | 0.64266 | 4 | 0 | 4 |
| SLC2A2 | LRIT1 | 0.641985 | 3 | 0 | 3 |
| SLC2A2 | NEURL1 | 0.64135 | 3 | 0 | 3 |
| SLC2A2 | SIK2 | 0.638999 | 3 | 0 | 3 |
| SLC2A2 | UBQLN3 | 0.637835 | 4 | 0 | 3 |
For details and further investigation, click here
