| Full name: ribonuclease A family member 3 | Alias Symbol: ECP|RAF1 | ||
| Type: protein-coding gene | Cytoband: 14q11.2 | ||
| Entrez ID: 6037 | HGNC ID: HGNC:10046 | Ensembl Gene: ENSG00000169397 | OMIM ID: 131398 |
| Drug and gene relationship at DGIdb | |||
Expression of RNASE3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RNASE3 | 6037 | 206851_at | 0.0955 | 0.7018 | |
| GSE20347 | RNASE3 | 6037 | 206851_at | 0.0201 | 0.8636 | |
| GSE23400 | RNASE3 | 6037 | 206851_at | -0.0766 | 0.0566 | |
| GSE26886 | RNASE3 | 6037 | 206851_at | -0.1394 | 0.2628 | |
| GSE29001 | RNASE3 | 6037 | 206851_at | 0.0321 | 0.8873 | |
| GSE38129 | RNASE3 | 6037 | 206851_at | -0.0617 | 0.4808 | |
| GSE45670 | RNASE3 | 6037 | 206851_at | 0.2442 | 0.0105 | |
| GSE53622 | RNASE3 | 6037 | 34594 | 0.8320 | 0.0000 | |
| GSE53624 | RNASE3 | 6037 | 34594 | 0.7066 | 0.0000 | |
| GSE63941 | RNASE3 | 6037 | 206851_at | 0.2028 | 0.2024 | |
| GSE77861 | RNASE3 | 6037 | 206851_at | -0.0100 | 0.9372 | |
| GSE97050 | RNASE3 | 6037 | A_23_P163025 | 0.4058 | 0.4632 | |
| TCGA | RNASE3 | 6037 | RNAseq | 1.5547 | 0.1080 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RNASE3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RNASE3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RNASE3 | 6037 | 9 | 3 | 18 | |
| GSE20123 | RNASE3 | 6037 | 8 | 3 | 19 | |
| GSE43470 | RNASE3 | 6037 | 7 | 1 | 35 | |
| GSE46452 | RNASE3 | 6037 | 19 | 2 | 38 | |
| GSE47630 | RNASE3 | 6037 | 10 | 10 | 20 | |
| GSE54993 | RNASE3 | 6037 | 3 | 11 | 56 | |
| GSE54994 | RNASE3 | 6037 | 18 | 5 | 30 | |
| GSE60625 | RNASE3 | 6037 | 0 | 2 | 9 | |
| GSE74703 | RNASE3 | 6037 | 6 | 1 | 29 | |
| GSE74704 | RNASE3 | 6037 | 4 | 2 | 14 | |
| TCGA | RNASE3 | 6037 | 27 | 16 | 53 |
Total number of gains: 111; Total number of losses: 56; Total Number of normals: 321.
Somatic mutations of RNASE3:
Generating mutation plots.
Highly correlated genes for RNASE3:
Showing top 20/688 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RNASE3 | MAPK11 | 0.766899 | 3 | 0 | 3 |
| RNASE3 | CLC | 0.749139 | 3 | 0 | 3 |
| RNASE3 | HORMAD2 | 0.736111 | 3 | 0 | 3 |
| RNASE3 | IFNA7 | 0.716401 | 5 | 0 | 5 |
| RNASE3 | CD69 | 0.707948 | 3 | 0 | 3 |
| RNASE3 | GGT5 | 0.704733 | 3 | 0 | 3 |
| RNASE3 | RBP4 | 0.699153 | 3 | 0 | 3 |
| RNASE3 | GAD2 | 0.692953 | 6 | 0 | 6 |
| RNASE3 | PDZD3 | 0.692679 | 6 | 0 | 6 |
| RNASE3 | KCNA1 | 0.685475 | 5 | 0 | 5 |
| RNASE3 | RHAG | 0.677398 | 3 | 0 | 3 |
| RNASE3 | LENEP | 0.675833 | 7 | 0 | 7 |
| RNASE3 | TTR | 0.674728 | 5 | 0 | 4 |
| RNASE3 | IFNA14 | 0.673522 | 5 | 0 | 4 |
| RNASE3 | LINC01119 | 0.669712 | 3 | 0 | 3 |
| RNASE3 | OR10H3 | 0.668361 | 8 | 0 | 7 |
| RNASE3 | KRTAP5-8 | 0.667923 | 6 | 0 | 5 |
| RNASE3 | IFITM3 | 0.665586 | 3 | 0 | 3 |
| RNASE3 | TCL1B | 0.66275 | 6 | 0 | 5 |
| RNASE3 | TAS2R4 | 0.662243 | 6 | 0 | 6 |
For details and further investigation, click here
