| Full name: solute carrier family 5 member 7 | Alias Symbol: hCHT|CHT1 | ||
| Type: protein-coding gene | Cytoband: 2q12.3 | ||
| Entrez ID: 60482 | HGNC ID: HGNC:14025 | Ensembl Gene: ENSG00000115665 | OMIM ID: 608761 |
| Drug and gene relationship at DGIdb | |||
SLC5A7 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa05231 | Choline metabolism in cancer |
Expression of SLC5A7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC5A7 | 60482 | 220722_s_at | -0.0027 | 0.9932 | |
| GSE20347 | SLC5A7 | 60482 | 220722_s_at | 0.0153 | 0.9000 | |
| GSE23400 | SLC5A7 | 60482 | 220722_s_at | -0.1208 | 0.0025 | |
| GSE26886 | SLC5A7 | 60482 | 220722_s_at | -0.1582 | 0.2814 | |
| GSE29001 | SLC5A7 | 60482 | 220722_s_at | -0.2645 | 0.0686 | |
| GSE38129 | SLC5A7 | 60482 | 220722_s_at | -0.1236 | 0.1961 | |
| GSE45670 | SLC5A7 | 60482 | 220722_s_at | 0.1019 | 0.4025 | |
| GSE53622 | SLC5A7 | 60482 | 41961 | -0.5132 | 0.0414 | |
| GSE53624 | SLC5A7 | 60482 | 41961 | -0.1320 | 0.3671 | |
| GSE63941 | SLC5A7 | 60482 | 220722_s_at | -0.0176 | 0.9252 | |
| GSE77861 | SLC5A7 | 60482 | 220722_s_at | -0.0953 | 0.3816 | |
| TCGA | SLC5A7 | 60482 | RNAseq | -2.7887 | 0.0029 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SLC5A7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC5A7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC5A7 | 60482 | 3 | 2 | 25 | |
| GSE20123 | SLC5A7 | 60482 | 3 | 2 | 25 | |
| GSE43470 | SLC5A7 | 60482 | 3 | 1 | 39 | |
| GSE46452 | SLC5A7 | 60482 | 1 | 4 | 54 | |
| GSE47630 | SLC5A7 | 60482 | 7 | 0 | 33 | |
| GSE54993 | SLC5A7 | 60482 | 0 | 6 | 64 | |
| GSE54994 | SLC5A7 | 60482 | 10 | 0 | 43 | |
| GSE60625 | SLC5A7 | 60482 | 0 | 3 | 8 | |
| GSE74703 | SLC5A7 | 60482 | 3 | 1 | 32 | |
| GSE74704 | SLC5A7 | 60482 | 2 | 2 | 16 | |
| TCGA | SLC5A7 | 60482 | 31 | 6 | 59 |
Total number of gains: 63; Total number of losses: 27; Total Number of normals: 398.
Somatic mutations of SLC5A7:
Generating mutation plots.
Highly correlated genes for SLC5A7:
Showing top 20/922 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC5A7 | EPOR | 0.751188 | 6 | 0 | 6 |
| SLC5A7 | KIR2DS2 | 0.74182 | 4 | 0 | 4 |
| SLC5A7 | UMOD | 0.738934 | 4 | 0 | 4 |
| SLC5A7 | KRT76 | 0.727828 | 4 | 0 | 4 |
| SLC5A7 | ADAM22 | 0.725556 | 4 | 0 | 4 |
| SLC5A7 | RNF17 | 0.721878 | 4 | 0 | 4 |
| SLC5A7 | SLC28A2 | 0.720783 | 4 | 0 | 4 |
| SLC5A7 | NXPE4 | 0.720475 | 5 | 0 | 5 |
| SLC5A7 | RFPL2 | 0.715069 | 5 | 0 | 5 |
| SLC5A7 | MUC5AC | 0.709796 | 5 | 0 | 5 |
| SLC5A7 | TSHB | 0.706319 | 4 | 0 | 4 |
| SLC5A7 | LRTM1 | 0.702241 | 4 | 0 | 4 |
| SLC5A7 | PTPRN2 | 0.699047 | 4 | 0 | 4 |
| SLC5A7 | MTAP | 0.694804 | 4 | 0 | 4 |
| SLC5A7 | OR5I1 | 0.691457 | 4 | 0 | 4 |
| SLC5A7 | ADAMTS12 | 0.690845 | 4 | 0 | 4 |
| SLC5A7 | SLC4A4 | 0.690503 | 5 | 0 | 4 |
| SLC5A7 | SLC35F6 | 0.681316 | 3 | 0 | 3 |
| SLC5A7 | SLC17A3 | 0.680895 | 4 | 0 | 4 |
| SLC5A7 | SEZ6L | 0.677971 | 4 | 0 | 4 |
For details and further investigation, click here
