RRAD

 

Full name: RRAD, Ras related glycolysis inhibitor and calcium channel regulator Alias Symbol: REM3|RAD
Type: protein-coding gene Cytoband: 16q22.1
Entrez ID: 6236 HGNC ID: HGNC:10446 Ensembl Gene: ENSG00000166592 OMIM ID: 179503
Drug and gene relationship at DGIdb

 

Expression of RRAD:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 RRAD 6236 204803_s_at -2.5442 0.0517
GSE20347 RRAD 6236 204803_s_at -1.8573 0.0000
GSE23400 RRAD 6236 204803_s_at -1.1729 0.0000
GSE26886 RRAD 6236 204803_s_at -2.9677 0.0000
GSE29001 RRAD 6236 204803_s_at -2.3059 0.0004
GSE38129 RRAD 6236 204803_s_at -1.8396 0.0000
GSE45670 RRAD 6236 204803_s_at -0.9036 0.1368
GSE53622 RRAD 6236 88060 -2.2885 0.0000
GSE53624 RRAD 6236 88060 -2.3694 0.0000
GSE63941 RRAD 6236 204803_s_at -0.7542 0.2281
GSE77861 RRAD 6236 204803_s_at -0.2944 0.4315
GSE97050 RRAD 6236 A_24_P262127 -0.1075 0.6737
SRP007169 RRAD 6236 RNAseq -1.6198 0.0045
SRP064894 RRAD 6236 RNAseq -2.6538 0.0000
SRP133303 RRAD 6236 RNAseq -1.7692 0.0009
SRP159526 RRAD 6236 RNAseq -2.9196 0.0004
SRP219564 RRAD 6236 RNAseq -1.3901 0.0836
TCGA RRAD 6236 RNAseq -0.0137 0.9589

Upregulated datasets: 0; Downregulated datasets: 11.  


 

Survival by RRAD expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of RRAD:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 RRAD 6236 8 2 20
GSE20123 RRAD 6236 8 2 20
GSE43470 RRAD 6236 1 8 34
GSE46452 RRAD 6236 38 1 20
GSE47630 RRAD 6236 10 8 22
GSE54993 RRAD 6236 2 4 64
GSE54994 RRAD 6236 8 10 35
GSE60625 RRAD 6236 4 0 7
GSE74703 RRAD 6236 1 5 30
GSE74704 RRAD 6236 5 1 14
TCGA RRAD 6236 31 11 54

Total number of gains: 116; Total number of losses: 52; Total Number of normals: 320.  


 

Somatic mutations of RRAD:

 

Generating mutation plots.

 

Highly correlated genes for RRAD:

 

Showing top 20/1101 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
RRADFCHO20.757088505
RRADEVC20.749086303
RRADRSPH30.737577303
RRADCCNYL10.73235303
RRADCCDC70.731372303
RRADCPEB40.729342505
RRADBOK0.72625404
RRADCLDND10.724724303
RRADENDOU0.7107451009
RRADNLRX10.7093211009
RRADFAM98A0.70808303
RRADSESN20.705108505
RRADKCTD60.703486605
RRADFAM174A0.703281505
RRADHIGD1A0.70272711010
RRADFBXL170.702717404
RRADFLII0.70246807
RRADSNRK0.700123909
RRADZNF503-AS10.698569404
RRADCRISP30.69821909

For details and further investigation, click here