| Full name: proline rich transmembrane protein 3 | Alias Symbol: FLJ33674 | ||
| Type: protein-coding gene | Cytoband: 3p25.3 | ||
| Entrez ID: 285368 | HGNC ID: HGNC:26591 | Ensembl Gene: ENSG00000163704 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of PRRT3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRRT3 | 285368 | 1556308_at | -0.2580 | 0.5168 | |
| GSE26886 | PRRT3 | 285368 | 1556308_at | -0.3997 | 0.0356 | |
| GSE45670 | PRRT3 | 285368 | 1556308_at | -0.6290 | 0.0014 | |
| GSE53622 | PRRT3 | 285368 | 44169 | -0.8087 | 0.0000 | |
| GSE53624 | PRRT3 | 285368 | 44169 | -0.6827 | 0.0000 | |
| GSE63941 | PRRT3 | 285368 | 1556308_at | -1.6702 | 0.0042 | |
| GSE77861 | PRRT3 | 285368 | 1556308_at | -0.2030 | 0.0761 | |
| GSE97050 | PRRT3 | 285368 | A_23_P80626 | -0.2541 | 0.5063 | |
| SRP007169 | PRRT3 | 285368 | RNAseq | -2.9686 | 0.0000 | |
| SRP008496 | PRRT3 | 285368 | RNAseq | -2.8195 | 0.0000 | |
| SRP064894 | PRRT3 | 285368 | RNAseq | -1.2781 | 0.0000 | |
| SRP133303 | PRRT3 | 285368 | RNAseq | -1.0663 | 0.0000 | |
| SRP159526 | PRRT3 | 285368 | RNAseq | -0.7473 | 0.0662 | |
| SRP193095 | PRRT3 | 285368 | RNAseq | -0.1537 | 0.3374 | |
| SRP219564 | PRRT3 | 285368 | RNAseq | -0.8892 | 0.0075 | |
| TCGA | PRRT3 | 285368 | RNAseq | -0.1704 | 0.1217 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by PRRT3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRRT3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRRT3 | 285368 | 1 | 18 | 11 | |
| GSE20123 | PRRT3 | 285368 | 1 | 18 | 11 | |
| GSE43470 | PRRT3 | 285368 | 1 | 20 | 22 | |
| GSE46452 | PRRT3 | 285368 | 2 | 17 | 40 | |
| GSE47630 | PRRT3 | 285368 | 2 | 23 | 15 | |
| GSE54993 | PRRT3 | 285368 | 6 | 1 | 63 | |
| GSE54994 | PRRT3 | 285368 | 3 | 31 | 19 | |
| GSE60625 | PRRT3 | 285368 | 5 | 0 | 6 | |
| GSE74703 | PRRT3 | 285368 | 1 | 16 | 19 | |
| GSE74704 | PRRT3 | 285368 | 1 | 11 | 8 | |
| TCGA | PRRT3 | 285368 | 5 | 65 | 26 |
Total number of gains: 28; Total number of losses: 220; Total Number of normals: 240.
Somatic mutations of PRRT3:
Generating mutation plots.
Highly correlated genes for PRRT3:
Showing top 20/683 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRRT3 | SLC9A6 | 0.707234 | 3 | 0 | 3 |
| PRRT3 | SWAP70 | 0.695223 | 3 | 0 | 3 |
| PRRT3 | CDKL1 | 0.691844 | 3 | 0 | 3 |
| PRRT3 | CPPED1 | 0.680231 | 6 | 0 | 6 |
| PRRT3 | GSTT2 | 0.675696 | 3 | 0 | 3 |
| PRRT3 | C16orf72 | 0.673842 | 3 | 0 | 3 |
| PRRT3 | GLCE | 0.671312 | 4 | 0 | 3 |
| PRRT3 | ACAA1 | 0.663183 | 5 | 0 | 5 |
| PRRT3 | TEX264 | 0.661901 | 4 | 0 | 4 |
| PRRT3 | STAM | 0.661712 | 3 | 0 | 3 |
| PRRT3 | ATP12A | 0.660092 | 3 | 0 | 3 |
| PRRT3 | PRKAR2A | 0.656355 | 5 | 0 | 5 |
| PRRT3 | NDST2 | 0.652522 | 6 | 0 | 6 |
| PRRT3 | ANO10 | 0.650407 | 7 | 0 | 7 |
| PRRT3 | ATP6V0C | 0.647354 | 3 | 0 | 3 |
| PRRT3 | LINC00330 | 0.643964 | 4 | 0 | 4 |
| PRRT3 | YME1L1 | 0.640855 | 3 | 0 | 3 |
| PRRT3 | DTWD1 | 0.640425 | 3 | 0 | 3 |
| PRRT3 | BTBD1 | 0.640193 | 4 | 0 | 3 |
| PRRT3 | VSIG2 | 0.639445 | 6 | 0 | 5 |
For details and further investigation, click here
