| Full name: proteasome subunit alpha 2 | Alias Symbol: MU|HC3|PMSA2 | ||
| Type: protein-coding gene | Cytoband: 7p14.1 | ||
| Entrez ID: 5683 | HGNC ID: HGNC:9531 | Ensembl Gene: ENSG00000106588 | OMIM ID: 176842 |
| Drug and gene relationship at DGIdb | |||
Expression of PSMA2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PSMA2 | 5683 | 201317_s_at | 0.2651 | 0.4305 | |
| GSE20347 | PSMA2 | 5683 | 201317_s_at | 0.5252 | 0.0110 | |
| GSE23400 | PSMA2 | 5683 | 201317_s_at | 0.6425 | 0.0000 | |
| GSE26886 | PSMA2 | 5683 | 201317_s_at | 0.0713 | 0.7813 | |
| GSE29001 | PSMA2 | 5683 | 201317_s_at | 0.3855 | 0.4068 | |
| GSE38129 | PSMA2 | 5683 | 201317_s_at | 0.6279 | 0.0001 | |
| GSE45670 | PSMA2 | 5683 | 201317_s_at | 0.4190 | 0.0020 | |
| GSE63941 | PSMA2 | 5683 | 201317_s_at | 0.7865 | 0.0061 | |
| GSE77861 | PSMA2 | 5683 | 201317_s_at | 0.1684 | 0.5841 | |
| GSE97050 | PSMA2 | 5683 | A_23_P345591 | 0.2359 | 0.3765 | |
| SRP007169 | PSMA2 | 5683 | RNAseq | -0.1797 | 0.5872 | |
| SRP008496 | PSMA2 | 5683 | RNAseq | 0.0352 | 0.8902 | |
| SRP064894 | PSMA2 | 5683 | RNAseq | 0.4246 | 0.0411 | |
| SRP133303 | PSMA2 | 5683 | RNAseq | 0.7642 | 0.0000 | |
| SRP159526 | PSMA2 | 5683 | RNAseq | 0.1793 | 0.4862 | |
| SRP193095 | PSMA2 | 5683 | RNAseq | -0.0454 | 0.7865 | |
| SRP219564 | PSMA2 | 5683 | RNAseq | 0.1038 | 0.7618 | |
| TCGA | PSMA2 | 5683 | RNAseq | 0.1181 | 0.0137 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PSMA2 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of PSMA2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PSMA2 | 5683 | 14 | 0 | 16 | |
| GSE20123 | PSMA2 | 5683 | 13 | 0 | 17 | |
| GSE43470 | PSMA2 | 5683 | 4 | 0 | 39 | |
| GSE46452 | PSMA2 | 5683 | 11 | 1 | 47 | |
| GSE47630 | PSMA2 | 5683 | 8 | 1 | 31 | |
| GSE54993 | PSMA2 | 5683 | 0 | 7 | 63 | |
| GSE54994 | PSMA2 | 5683 | 17 | 3 | 33 | |
| GSE60625 | PSMA2 | 5683 | 0 | 0 | 11 | |
| GSE74703 | PSMA2 | 5683 | 4 | 0 | 32 | |
| GSE74704 | PSMA2 | 5683 | 7 | 0 | 13 | |
| TCGA | PSMA2 | 5683 | 50 | 7 | 39 |
Total number of gains: 128; Total number of losses: 19; Total Number of normals: 341.
Somatic mutations of PSMA2:
Generating mutation plots.
Highly correlated genes for PSMA2:
Showing top 20/1222 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PSMA2 | RPL7L1 | 0.780967 | 3 | 0 | 3 |
| PSMA2 | NCOA3 | 0.765623 | 3 | 0 | 3 |
| PSMA2 | OSTC | 0.748088 | 3 | 0 | 3 |
| PSMA2 | SF3B6 | 0.746373 | 3 | 0 | 3 |
| PSMA2 | NSA2 | 0.741847 | 3 | 0 | 3 |
| PSMA2 | SARNP | 0.736338 | 3 | 0 | 3 |
| PSMA2 | SLC25A24 | 0.736147 | 7 | 0 | 6 |
| PSMA2 | CHCHD2 | 0.729463 | 9 | 0 | 9 |
| PSMA2 | METAP2 | 0.728069 | 8 | 0 | 7 |
| PSMA2 | LSM5 | 0.724859 | 10 | 0 | 8 |
| PSMA2 | RNF181 | 0.718919 | 3 | 0 | 3 |
| PSMA2 | RPA3 | 0.717993 | 10 | 0 | 8 |
| PSMA2 | POC5 | 0.716843 | 3 | 0 | 3 |
| PSMA2 | GTDC1 | 0.716286 | 3 | 0 | 3 |
| PSMA2 | XPR1 | 0.708736 | 4 | 0 | 4 |
| PSMA2 | GFM2 | 0.707277 | 3 | 0 | 3 |
| PSMA2 | MRPL32 | 0.706835 | 6 | 0 | 5 |
| PSMA2 | FAN1 | 0.703521 | 3 | 0 | 3 |
| PSMA2 | TP53RK | 0.703205 | 3 | 0 | 3 |
| PSMA2 | PSMA4 | 0.70195 | 9 | 0 | 8 |
For details and further investigation, click here
