| Full name: general transcription factor IIE subunit 2 | Alias Symbol: TFIIE-B|FE|TF2E2 | ||
| Type: protein-coding gene | Cytoband: 8p12 | ||
| Entrez ID: 2961 | HGNC ID: HGNC:4651 | Ensembl Gene: ENSG00000197265 | OMIM ID: 189964 |
| Drug and gene relationship at DGIdb | |||
Expression of GTF2E2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GTF2E2 | 2961 | 202680_at | 0.6133 | 0.1113 | |
| GSE20347 | GTF2E2 | 2961 | 202680_at | 0.5429 | 0.0001 | |
| GSE23400 | GTF2E2 | 2961 | 202680_at | 0.5076 | 0.0000 | |
| GSE26886 | GTF2E2 | 2961 | 202680_at | -0.1207 | 0.5576 | |
| GSE29001 | GTF2E2 | 2961 | 202680_at | 0.4704 | 0.1274 | |
| GSE38129 | GTF2E2 | 2961 | 202680_at | 0.4456 | 0.0005 | |
| GSE45670 | GTF2E2 | 2961 | 202680_at | 0.5613 | 0.0028 | |
| GSE53622 | GTF2E2 | 2961 | 109088 | 0.3479 | 0.0000 | |
| GSE53624 | GTF2E2 | 2961 | 109088 | 0.1233 | 0.1787 | |
| GSE63941 | GTF2E2 | 2961 | 202680_at | -0.0760 | 0.8970 | |
| GSE77861 | GTF2E2 | 2961 | 202680_at | 0.6842 | 0.0801 | |
| GSE97050 | GTF2E2 | 2961 | A_23_P94118 | 0.2054 | 0.4912 | |
| SRP007169 | GTF2E2 | 2961 | RNAseq | 0.2277 | 0.5686 | |
| SRP008496 | GTF2E2 | 2961 | RNAseq | 0.0886 | 0.7462 | |
| SRP064894 | GTF2E2 | 2961 | RNAseq | 0.4497 | 0.0132 | |
| SRP133303 | GTF2E2 | 2961 | RNAseq | 0.0812 | 0.6556 | |
| SRP159526 | GTF2E2 | 2961 | RNAseq | 0.2057 | 0.5643 | |
| SRP193095 | GTF2E2 | 2961 | RNAseq | -0.0254 | 0.8689 | |
| SRP219564 | GTF2E2 | 2961 | RNAseq | -0.1759 | 0.5996 | |
| TCGA | GTF2E2 | 2961 | RNAseq | 0.1186 | 0.0806 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GTF2E2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GTF2E2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GTF2E2 | 2961 | 4 | 10 | 16 | |
| GSE20123 | GTF2E2 | 2961 | 4 | 10 | 16 | |
| GSE43470 | GTF2E2 | 2961 | 4 | 7 | 32 | |
| GSE46452 | GTF2E2 | 2961 | 13 | 13 | 33 | |
| GSE47630 | GTF2E2 | 2961 | 10 | 8 | 22 | |
| GSE54993 | GTF2E2 | 2961 | 2 | 15 | 53 | |
| GSE54994 | GTF2E2 | 2961 | 11 | 15 | 27 | |
| GSE60625 | GTF2E2 | 2961 | 3 | 0 | 8 | |
| GSE74703 | GTF2E2 | 2961 | 4 | 6 | 26 | |
| GSE74704 | GTF2E2 | 2961 | 3 | 7 | 10 | |
| TCGA | GTF2E2 | 2961 | 18 | 41 | 37 |
Total number of gains: 76; Total number of losses: 132; Total Number of normals: 280.
Somatic mutations of GTF2E2:
Generating mutation plots.
Highly correlated genes for GTF2E2:
Showing top 20/1307 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GTF2E2 | CENPBD1 | 0.79281 | 3 | 0 | 3 |
| GTF2E2 | PPP1R35 | 0.760531 | 3 | 0 | 3 |
| GTF2E2 | ISY1 | 0.751227 | 3 | 0 | 3 |
| GTF2E2 | EME1 | 0.749768 | 4 | 0 | 4 |
| GTF2E2 | TRAF7 | 0.746983 | 3 | 0 | 3 |
| GTF2E2 | SPNS1 | 0.724808 | 3 | 0 | 3 |
| GTF2E2 | CPNE2 | 0.72383 | 3 | 0 | 3 |
| GTF2E2 | IAH1 | 0.721886 | 3 | 0 | 3 |
| GTF2E2 | VCPIP1 | 0.720095 | 3 | 0 | 3 |
| GTF2E2 | ZCCHC17 | 0.718883 | 3 | 0 | 3 |
| GTF2E2 | NENF | 0.715738 | 3 | 0 | 3 |
| GTF2E2 | SLC7A6OS | 0.714667 | 4 | 0 | 4 |
| GTF2E2 | UHRF1BP1 | 0.712299 | 3 | 0 | 3 |
| GTF2E2 | TCTN3 | 0.711803 | 3 | 0 | 3 |
| GTF2E2 | KREMEN1 | 0.711503 | 3 | 0 | 3 |
| GTF2E2 | NEK6 | 0.711306 | 3 | 0 | 3 |
| GTF2E2 | SLC39A10 | 0.709596 | 4 | 0 | 3 |
| GTF2E2 | TRUB1 | 0.705895 | 5 | 0 | 5 |
| GTF2E2 | TMTC3 | 0.703248 | 3 | 0 | 3 |
| GTF2E2 | NINJ1 | 0.702427 | 3 | 0 | 3 |
For details and further investigation, click here
