| Full name: tectonic family member 3 | Alias Symbol: DKFZP564D116|TECT3|JBTS18 | ||
| Type: protein-coding gene | Cytoband: 10q24.1 | ||
| Entrez ID: 26123 | HGNC ID: HGNC:24519 | Ensembl Gene: ENSG00000119977 | OMIM ID: 613847 |
| Drug and gene relationship at DGIdb | |||
Expression of TCTN3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TCTN3 | 26123 | 212121_at | 0.2244 | 0.6730 | |
| GSE20347 | TCTN3 | 26123 | 212123_at | 0.0518 | 0.7096 | |
| GSE23400 | TCTN3 | 26123 | 212123_at | -0.0062 | 0.8923 | |
| GSE26886 | TCTN3 | 26123 | 212123_at | 0.6312 | 0.0000 | |
| GSE29001 | TCTN3 | 26123 | 212123_at | -0.0734 | 0.6828 | |
| GSE38129 | TCTN3 | 26123 | 212123_at | 0.0191 | 0.8659 | |
| GSE45670 | TCTN3 | 26123 | 212123_at | 0.1066 | 0.2845 | |
| GSE53622 | TCTN3 | 26123 | 72219 | 0.2312 | 0.0008 | |
| GSE53624 | TCTN3 | 26123 | 72219 | 0.1520 | 0.0303 | |
| GSE63941 | TCTN3 | 26123 | 212121_at | -1.3973 | 0.0001 | |
| GSE77861 | TCTN3 | 26123 | 212123_at | 0.1106 | 0.5336 | |
| GSE97050 | TCTN3 | 26123 | A_32_P2738 | 0.5225 | 0.0835 | |
| SRP007169 | TCTN3 | 26123 | RNAseq | 0.1954 | 0.5857 | |
| SRP008496 | TCTN3 | 26123 | RNAseq | 0.5074 | 0.0267 | |
| SRP064894 | TCTN3 | 26123 | RNAseq | 0.3051 | 0.0594 | |
| SRP133303 | TCTN3 | 26123 | RNAseq | 0.2024 | 0.1177 | |
| SRP159526 | TCTN3 | 26123 | RNAseq | 0.3502 | 0.0600 | |
| SRP193095 | TCTN3 | 26123 | RNAseq | 0.1589 | 0.0746 | |
| SRP219564 | TCTN3 | 26123 | RNAseq | 0.3085 | 0.2846 | |
| TCGA | TCTN3 | 26123 | RNAseq | -0.0341 | 0.5040 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by TCTN3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TCTN3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TCTN3 | 26123 | 0 | 8 | 22 | |
| GSE20123 | TCTN3 | 26123 | 0 | 7 | 23 | |
| GSE43470 | TCTN3 | 26123 | 0 | 7 | 36 | |
| GSE46452 | TCTN3 | 26123 | 0 | 11 | 48 | |
| GSE47630 | TCTN3 | 26123 | 2 | 14 | 24 | |
| GSE54993 | TCTN3 | 26123 | 7 | 0 | 63 | |
| GSE54994 | TCTN3 | 26123 | 2 | 10 | 41 | |
| GSE60625 | TCTN3 | 26123 | 0 | 0 | 11 | |
| GSE74703 | TCTN3 | 26123 | 0 | 5 | 31 | |
| GSE74704 | TCTN3 | 26123 | 0 | 4 | 16 | |
| TCGA | TCTN3 | 26123 | 6 | 27 | 63 |
Total number of gains: 17; Total number of losses: 93; Total Number of normals: 378.
Somatic mutations of TCTN3:
Generating mutation plots.
Highly correlated genes for TCTN3:
Showing top 20/891 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TCTN3 | CTBP2 | 0.823782 | 3 | 0 | 3 |
| TCTN3 | TNFRSF19 | 0.770284 | 3 | 0 | 3 |
| TCTN3 | PMPCB | 0.762477 | 3 | 0 | 3 |
| TCTN3 | SEC22C | 0.761179 | 5 | 0 | 5 |
| TCTN3 | CREB3 | 0.758072 | 3 | 0 | 3 |
| TCTN3 | UBTD2 | 0.756863 | 3 | 0 | 3 |
| TCTN3 | TTC19 | 0.735582 | 3 | 0 | 3 |
| TCTN3 | A1BG | 0.734238 | 3 | 0 | 3 |
| TCTN3 | USP34 | 0.732639 | 3 | 0 | 3 |
| TCTN3 | RNF113A | 0.726306 | 3 | 0 | 3 |
| TCTN3 | PDPR | 0.721499 | 3 | 0 | 3 |
| TCTN3 | BMP2 | 0.721428 | 3 | 0 | 3 |
| TCTN3 | LRP3 | 0.720434 | 3 | 0 | 3 |
| TCTN3 | LOXL4 | 0.720152 | 3 | 0 | 3 |
| TCTN3 | C11orf96 | 0.71871 | 3 | 0 | 3 |
| TCTN3 | CPT1A | 0.717202 | 3 | 0 | 3 |
| TCTN3 | YBEY | 0.7166 | 3 | 0 | 3 |
| TCTN3 | ABCB10 | 0.716016 | 3 | 0 | 3 |
| TCTN3 | FBXO31 | 0.715035 | 3 | 0 | 3 |
| TCTN3 | GTF2E2 | 0.711803 | 3 | 0 | 3 |
For details and further investigation, click here
