| Full name: isoamyl acetate hydrolyzing esterase 1 (putative) | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2p25.1 | ||
| Entrez ID: 285148 | HGNC ID: HGNC:27696 | Ensembl Gene: ENSG00000134330 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of IAH1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IAH1 | 285148 | 230621_at | 0.4423 | 0.6370 | |
| GSE26886 | IAH1 | 285148 | 230621_at | 1.1820 | 0.0014 | |
| GSE45670 | IAH1 | 285148 | 225908_at | -0.0033 | 0.9860 | |
| GSE53622 | IAH1 | 285148 | 85702 | 0.3206 | 0.0001 | |
| GSE53624 | IAH1 | 285148 | 85702 | 0.4620 | 0.0000 | |
| GSE63941 | IAH1 | 285148 | 230621_at | 2.6511 | 0.0010 | |
| GSE77861 | IAH1 | 285148 | 225908_at | 0.4672 | 0.0191 | |
| GSE97050 | IAH1 | 285148 | A_23_P17287 | -0.0295 | 0.9503 | |
| SRP007169 | IAH1 | 285148 | RNAseq | 0.1024 | 0.7416 | |
| SRP008496 | IAH1 | 285148 | RNAseq | 0.3605 | 0.1741 | |
| SRP064894 | IAH1 | 285148 | RNAseq | 0.6247 | 0.0028 | |
| SRP133303 | IAH1 | 285148 | RNAseq | 0.7262 | 0.0000 | |
| SRP159526 | IAH1 | 285148 | RNAseq | 0.6853 | 0.0073 | |
| SRP193095 | IAH1 | 285148 | RNAseq | 0.3483 | 0.0061 | |
| SRP219564 | IAH1 | 285148 | RNAseq | 0.3920 | 0.3095 | |
| TCGA | IAH1 | 285148 | RNAseq | 0.1575 | 0.0062 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by IAH1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IAH1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IAH1 | 285148 | 11 | 2 | 17 | |
| GSE20123 | IAH1 | 285148 | 11 | 2 | 17 | |
| GSE43470 | IAH1 | 285148 | 2 | 1 | 40 | |
| GSE46452 | IAH1 | 285148 | 3 | 4 | 52 | |
| GSE47630 | IAH1 | 285148 | 7 | 0 | 33 | |
| GSE54993 | IAH1 | 285148 | 0 | 7 | 63 | |
| GSE54994 | IAH1 | 285148 | 11 | 1 | 41 | |
| GSE60625 | IAH1 | 285148 | 0 | 3 | 8 | |
| GSE74703 | IAH1 | 285148 | 2 | 0 | 34 | |
| GSE74704 | IAH1 | 285148 | 9 | 1 | 10 | |
| TCGA | IAH1 | 285148 | 34 | 5 | 57 |
Total number of gains: 90; Total number of losses: 26; Total Number of normals: 372.
Somatic mutations of IAH1:
Generating mutation plots.
Highly correlated genes for IAH1:
Showing top 20/855 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IAH1 | PET117 | 0.834751 | 3 | 0 | 3 |
| IAH1 | ABCB6 | 0.832722 | 3 | 0 | 3 |
| IAH1 | FANCL | 0.790178 | 4 | 0 | 4 |
| IAH1 | NOL9 | 0.770819 | 3 | 0 | 3 |
| IAH1 | CPT1A | 0.761877 | 4 | 0 | 4 |
| IAH1 | SRRT | 0.75884 | 3 | 0 | 3 |
| IAH1 | DENND4A | 0.758532 | 3 | 0 | 3 |
| IAH1 | UEVLD | 0.749837 | 3 | 0 | 3 |
| IAH1 | ZCCHC8 | 0.748909 | 3 | 0 | 3 |
| IAH1 | TACC2 | 0.747032 | 3 | 0 | 3 |
| IAH1 | C1orf115 | 0.746767 | 3 | 0 | 3 |
| IAH1 | GMCL1 | 0.736858 | 3 | 0 | 3 |
| IAH1 | RTN4R | 0.733068 | 3 | 0 | 3 |
| IAH1 | U2SURP | 0.730955 | 4 | 0 | 4 |
| IAH1 | CMTM4 | 0.730792 | 3 | 0 | 3 |
| IAH1 | SORD | 0.728226 | 3 | 0 | 3 |
| IAH1 | EFHC1 | 0.72524 | 3 | 0 | 3 |
| IAH1 | CPSF7 | 0.724699 | 3 | 0 | 3 |
| IAH1 | ELP3 | 0.723888 | 4 | 0 | 4 |
| IAH1 | MKNK1 | 0.723595 | 3 | 0 | 3 |
For details and further investigation, click here
