WTIP

 

Full name: WT1 interacting protein Alias Symbol: 
Type: protein-coding gene Cytoband: 19q13.11
Entrez ID: 126374 HGNC ID: HGNC:20964 Ensembl Gene: ENSG00000142279 OMIM ID: 614790
Drug and gene relationship at DGIdb

 

WTIP involved pathways:

KEGG pathway Description View
hsa04390Hippo signaling pathway

 

Expression of WTIP:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 WTIP 126374 227411_at 0.1614 0.5852
GSE26886 WTIP 126374 227411_at 0.5091 0.0092
GSE45670 WTIP 126374 227411_at -0.1380 0.3730
GSE53622 WTIP 126374 65819 -0.1230 0.4013
GSE53624 WTIP 126374 65819 0.3836 0.0007
GSE63941 WTIP 126374 227411_at -1.4756 0.0003
GSE77861 WTIP 126374 227411_at 0.0674 0.7333
GSE97050 WTIP 126374 A_33_P3381948 -0.1400 0.6159
SRP007169 WTIP 126374 RNAseq 0.5249 0.2621
SRP008496 WTIP 126374 RNAseq 0.8930 0.0080
SRP064894 WTIP 126374 RNAseq 0.3562 0.1508
SRP133303 WTIP 126374 RNAseq -0.0115 0.8804
SRP159526 WTIP 126374 RNAseq 0.4242 0.2307
SRP193095 WTIP 126374 RNAseq 0.4500 0.0019
SRP219564 WTIP 126374 RNAseq -0.2766 0.5400
TCGA WTIP 126374 RNAseq -0.2572 0.0334

Upregulated datasets: 0; Downregulated datasets: 1.  

 

Survival by WTIP expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of WTIP:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 WTIP 126374 6 5 19
GSE20123 WTIP 126374 6 4 20
GSE43470 WTIP 126374 5 7 31
GSE46452 WTIP 126374 48 1 10
GSE47630 WTIP 126374 9 5 26
GSE54993 WTIP 126374 17 3 50
GSE54994 WTIP 126374 9 9 35
GSE60625 WTIP 126374 9 0 2
GSE74703 WTIP 126374 5 4 27
GSE74704 WTIP 126374 6 2 12
TCGA WTIP 126374 19 11 66

Total number of gains: 139; Total number of losses: 51; Total Number of normals: 298.  

 

Somatic mutations of WTIP:

 

Generating mutation plots.

 

Highly correlated genes for WTIP:

 

Showing top 20/784 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
WTIPCHIC10.817008303
WTIPGYPC0.771024303
WTIPYTHDF30.770374303
WTIPPNKP0.766146303
WTIPMAPRE30.758335303
WTIPEFEMP20.741952707
WTIPGRIK20.740412404
WTIPDCHS10.733008403
WTIPSRI0.732523303
WTIPDSTYK0.730798303
WTIPZNF8270.729271404
WTIPHERC10.728924303
WTIPNAPB0.725328303
WTIPINMT0.725023303
WTIPKANSL30.718707303
WTIPC8orf440.716681303
WTIPPFN20.716035303
WTIPELFN10.715884303
WTIPTNFRSF10B0.715687303
WTIPEGR30.715549303

For details and further investigation, click here