| Full name: hydroxyacid oxidase 1 | Alias Symbol: GOX | ||
| Type: protein-coding gene | Cytoband: 20p12.3 | ||
| Entrez ID: 54363 | HGNC ID: HGNC:4809 | Ensembl Gene: ENSG00000101323 | OMIM ID: 605023 |
| Drug and gene relationship at DGIdb | |||
Expression of HAO1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HAO1 | 54363 | 220224_at | 0.0605 | 0.7660 | |
| GSE20347 | HAO1 | 54363 | 220224_at | 0.0556 | 0.3969 | |
| GSE23400 | HAO1 | 54363 | 220224_at | -0.0328 | 0.4084 | |
| GSE26886 | HAO1 | 54363 | 220224_at | -0.0249 | 0.8452 | |
| GSE29001 | HAO1 | 54363 | 220224_at | 0.0989 | 0.5369 | |
| GSE38129 | HAO1 | 54363 | 220224_at | -0.0478 | 0.3972 | |
| GSE45670 | HAO1 | 54363 | 220224_at | 0.0497 | 0.5088 | |
| GSE53622 | HAO1 | 54363 | 57935 | 0.3309 | 0.0248 | |
| GSE53624 | HAO1 | 54363 | 57935 | 0.0700 | 0.5742 | |
| GSE63941 | HAO1 | 54363 | 220224_at | -0.1902 | 0.1454 | |
| GSE77861 | HAO1 | 54363 | 220224_at | -0.0443 | 0.6006 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HAO1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HAO1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HAO1 | 54363 | 10 | 2 | 18 | |
| GSE20123 | HAO1 | 54363 | 10 | 2 | 18 | |
| GSE43470 | HAO1 | 54363 | 12 | 1 | 30 | |
| GSE46452 | HAO1 | 54363 | 26 | 1 | 32 | |
| GSE47630 | HAO1 | 54363 | 18 | 4 | 18 | |
| GSE54993 | HAO1 | 54363 | 1 | 14 | 55 | |
| GSE54994 | HAO1 | 54363 | 25 | 2 | 26 | |
| GSE60625 | HAO1 | 54363 | 0 | 0 | 11 | |
| GSE74703 | HAO1 | 54363 | 9 | 1 | 26 | |
| GSE74704 | HAO1 | 54363 | 5 | 1 | 14 | |
| TCGA | HAO1 | 54363 | 40 | 11 | 45 |
Total number of gains: 156; Total number of losses: 39; Total Number of normals: 293.
Somatic mutations of HAO1:
Generating mutation plots.
Highly correlated genes for HAO1:
Showing top 20/454 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HAO1 | IGFALS | 0.702042 | 3 | 0 | 3 |
| HAO1 | PEAK1 | 0.700102 | 4 | 0 | 4 |
| HAO1 | PCBP3 | 0.676031 | 3 | 0 | 3 |
| HAO1 | RHAG | 0.67468 | 4 | 0 | 4 |
| HAO1 | MSI1 | 0.668027 | 3 | 0 | 3 |
| HAO1 | DEC1 | 0.667776 | 3 | 0 | 3 |
| HAO1 | HOXB5 | 0.658983 | 3 | 0 | 3 |
| HAO1 | RUNX2 | 0.657834 | 4 | 0 | 3 |
| HAO1 | MPO | 0.657093 | 4 | 0 | 3 |
| HAO1 | SLC32A1 | 0.655593 | 3 | 0 | 3 |
| HAO1 | TLL1 | 0.653737 | 3 | 0 | 3 |
| HAO1 | CIITA | 0.653185 | 4 | 0 | 4 |
| HAO1 | SOX3 | 0.65109 | 4 | 0 | 3 |
| HAO1 | ARHGEF38 | 0.650715 | 5 | 0 | 5 |
| HAO1 | HECW1 | 0.650658 | 6 | 0 | 6 |
| HAO1 | DLG3-AS1 | 0.649862 | 3 | 0 | 3 |
| HAO1 | SLC17A7 | 0.64787 | 5 | 0 | 5 |
| HAO1 | LINC00311 | 0.642281 | 3 | 0 | 3 |
| HAO1 | CKM | 0.635832 | 4 | 0 | 3 |
| HAO1 | NTNG1 | 0.635806 | 4 | 0 | 3 |
For details and further investigation, click here
