| Full name: homeobox B5 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 17q21.32 | ||
| Entrez ID: 3215 | HGNC ID: HGNC:5116 | Ensembl Gene: ENSG00000120075 | OMIM ID: 142960 |
| Drug and gene relationship at DGIdb | |||
Expression of HOXB5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HOXB5 | 3215 | 205601_s_at | 0.1497 | 0.5596 | |
| GSE20347 | HOXB5 | 3215 | 205601_s_at | 0.1465 | 0.0483 | |
| GSE23400 | HOXB5 | 3215 | 205600_x_at | -0.0511 | 0.2601 | |
| GSE26886 | HOXB5 | 3215 | 205601_s_at | 0.3625 | 0.0094 | |
| GSE29001 | HOXB5 | 3215 | 205601_s_at | 0.3366 | 0.1450 | |
| GSE38129 | HOXB5 | 3215 | 205601_s_at | 0.0969 | 0.3949 | |
| GSE45670 | HOXB5 | 3215 | 205601_s_at | 0.1085 | 0.2336 | |
| GSE53622 | HOXB5 | 3215 | 53579 | 0.8526 | 0.0000 | |
| GSE53624 | HOXB5 | 3215 | 53579 | 1.4902 | 0.0000 | |
| GSE63941 | HOXB5 | 3215 | 205601_s_at | -0.3301 | 0.2662 | |
| GSE77861 | HOXB5 | 3215 | 205601_s_at | -0.0627 | 0.7323 | |
| GSE97050 | HOXB5 | 3215 | A_23_P363316 | 0.0757 | 0.7387 | |
| SRP159526 | HOXB5 | 3215 | RNAseq | 2.5194 | 0.0001 | |
| TCGA | HOXB5 | 3215 | RNAseq | 0.1080 | 0.6767 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by HOXB5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HOXB5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HOXB5 | 3215 | 5 | 2 | 23 | |
| GSE20123 | HOXB5 | 3215 | 5 | 2 | 23 | |
| GSE43470 | HOXB5 | 3215 | 3 | 1 | 39 | |
| GSE46452 | HOXB5 | 3215 | 32 | 0 | 27 | |
| GSE47630 | HOXB5 | 3215 | 9 | 0 | 31 | |
| GSE54993 | HOXB5 | 3215 | 2 | 4 | 64 | |
| GSE54994 | HOXB5 | 3215 | 10 | 6 | 37 | |
| GSE60625 | HOXB5 | 3215 | 4 | 0 | 7 | |
| GSE74703 | HOXB5 | 3215 | 3 | 1 | 32 | |
| GSE74704 | HOXB5 | 3215 | 4 | 1 | 15 | |
| TCGA | HOXB5 | 3215 | 27 | 6 | 63 |
Total number of gains: 104; Total number of losses: 23; Total Number of normals: 361.
Somatic mutations of HOXB5:
Generating mutation plots.
Highly correlated genes for HOXB5:
Showing top 20/495 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HOXB5 | FBLN7 | 0.751657 | 3 | 0 | 3 |
| HOXB5 | EPHA10 | 0.737685 | 3 | 0 | 3 |
| HOXB5 | FAM151A | 0.718091 | 3 | 0 | 3 |
| HOXB5 | SLC25A47 | 0.706223 | 3 | 0 | 3 |
| HOXB5 | NCAN | 0.698313 | 4 | 0 | 4 |
| HOXB5 | IL17F | 0.689948 | 3 | 0 | 3 |
| HOXB5 | PPM1J | 0.689315 | 3 | 0 | 3 |
| HOXB5 | CLCNKB | 0.684815 | 4 | 0 | 4 |
| HOXB5 | FERD3L | 0.684815 | 3 | 0 | 3 |
| HOXB5 | FAM71F1 | 0.683639 | 3 | 0 | 3 |
| HOXB5 | GPR150 | 0.668436 | 4 | 0 | 4 |
| HOXB5 | PGC | 0.663467 | 4 | 0 | 4 |
| HOXB5 | HAO1 | 0.658983 | 3 | 0 | 3 |
| HOXB5 | NTRK1 | 0.65736 | 3 | 0 | 3 |
| HOXB5 | SLC5A4 | 0.654339 | 4 | 0 | 4 |
| HOXB5 | HOXB-AS1 | 0.65094 | 3 | 0 | 3 |
| HOXB5 | C19orf81 | 0.650788 | 3 | 0 | 3 |
| HOXB5 | LILRA3 | 0.650512 | 5 | 0 | 5 |
| HOXB5 | CLSTN3 | 0.649743 | 4 | 0 | 3 |
| HOXB5 | AVPR2 | 0.648996 | 5 | 0 | 4 |
For details and further investigation, click here
