| Full name: myeloperoxidase | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 17q22 | ||
| Entrez ID: 4353 | HGNC ID: HGNC:7218 | Ensembl Gene: ENSG00000005381 | OMIM ID: 606989 |
| Drug and gene relationship at DGIdb | |||
Expression of MPO:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MPO | 4353 | 203948_s_at | 0.0274 | 0.9319 | |
| GSE20347 | MPO | 4353 | 203949_at | -0.0296 | 0.7035 | |
| GSE23400 | MPO | 4353 | 203948_s_at | -0.0549 | 0.0670 | |
| GSE26886 | MPO | 4353 | 203949_at | -0.2718 | 0.0126 | |
| GSE29001 | MPO | 4353 | 203949_at | 0.0242 | 0.9133 | |
| GSE38129 | MPO | 4353 | 203949_at | -0.0835 | 0.2847 | |
| GSE45670 | MPO | 4353 | 203948_s_at | 0.0137 | 0.9012 | |
| GSE53622 | MPO | 4353 | 21937 | -0.1116 | 0.1726 | |
| GSE53624 | MPO | 4353 | 21937 | -0.9350 | 0.0000 | |
| GSE63941 | MPO | 4353 | 203949_at | 0.0698 | 0.5832 | |
| GSE77861 | MPO | 4353 | 203949_at | -0.0752 | 0.5589 | |
| GSE97050 | MPO | 4353 | A_23_P141173 | -0.5960 | 0.2688 | |
| TCGA | MPO | 4353 | RNAseq | -0.1716 | 0.7828 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MPO expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MPO:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MPO | 4353 | 5 | 1 | 24 | |
| GSE20123 | MPO | 4353 | 5 | 1 | 24 | |
| GSE43470 | MPO | 4353 | 4 | 0 | 39 | |
| GSE46452 | MPO | 4353 | 32 | 0 | 27 | |
| GSE47630 | MPO | 4353 | 7 | 1 | 32 | |
| GSE54993 | MPO | 4353 | 2 | 5 | 63 | |
| GSE54994 | MPO | 4353 | 8 | 6 | 39 | |
| GSE60625 | MPO | 4353 | 4 | 0 | 7 | |
| GSE74703 | MPO | 4353 | 4 | 0 | 32 | |
| GSE74704 | MPO | 4353 | 4 | 1 | 15 | |
| TCGA | MPO | 4353 | 26 | 8 | 62 |
Total number of gains: 101; Total number of losses: 23; Total Number of normals: 364.
Somatic mutations of MPO:
Generating mutation plots.
Highly correlated genes for MPO:
Showing top 20/777 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MPO | BARHL2 | 0.779115 | 3 | 0 | 3 |
| MPO | MAMSTR | 0.703328 | 3 | 0 | 3 |
| MPO | TSKS | 0.695898 | 3 | 0 | 3 |
| MPO | GPR62 | 0.684862 | 4 | 0 | 4 |
| MPO | RNF222 | 0.683759 | 3 | 0 | 3 |
| MPO | SCGN | 0.682933 | 5 | 0 | 5 |
| MPO | PRODH2 | 0.680285 | 6 | 0 | 6 |
| MPO | RASGRF2 | 0.679835 | 3 | 0 | 3 |
| MPO | CORT | 0.677723 | 4 | 0 | 4 |
| MPO | ARL5C | 0.676677 | 3 | 0 | 3 |
| MPO | NOS1 | 0.676641 | 5 | 0 | 5 |
| MPO | PAPPA2 | 0.676425 | 6 | 0 | 6 |
| MPO | CLEC18C | 0.672594 | 3 | 0 | 3 |
| MPO | IVL | 0.666092 | 4 | 0 | 4 |
| MPO | TGM4 | 0.665731 | 3 | 0 | 3 |
| MPO | DNAI2 | 0.664629 | 5 | 0 | 4 |
| MPO | KRTAP5-5 | 0.663245 | 3 | 0 | 3 |
| MPO | IL21 | 0.662297 | 5 | 0 | 5 |
| MPO | PATE3 | 0.661762 | 3 | 0 | 3 |
| MPO | SLC2A11 | 0.65935 | 3 | 0 | 3 |
For details and further investigation, click here
