DEC1

 

Full name: deleted in esophageal cancer 1 Alias Symbol: CTS9
Type: non-coding RNA Cytoband: 9q33.1
Entrez ID: 50514 HGNC ID: HGNC:23658 Ensembl Gene: ENSG00000173077 OMIM ID: 604767
Drug and gene relationship at DGIdb

 

Expression of DEC1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 DEC1 50514 220781_at 0.0112 0.9683
GSE20347 DEC1 50514 220781_at 0.0272 0.6804
GSE23400 DEC1 50514 220781_at -0.0357 0.1226
GSE26886 DEC1 50514 220781_at -0.0877 0.3531
GSE29001 DEC1 50514 220781_at -0.1194 0.5049
GSE38129 DEC1 50514 220781_at 0.0175 0.7362
GSE45670 DEC1 50514 220781_at 0.1340 0.0754
GSE53622 DEC1 50514 20064 0.1147 0.1847
GSE53624 DEC1 50514 20064 0.3054 0.0084
GSE63941 DEC1 50514 220781_at -0.0740 0.6162
GSE77861 DEC1 50514 220781_at -0.0496 0.6129
TCGA DEC1 50514 RNAseq 3.0636 0.0149

Upregulated datasets: 1; Downregulated datasets: 0.  


 

Survival by DEC1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of DEC1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 DEC1 50514 5 10 15
GSE20123 DEC1 50514 5 10 15
GSE43470 DEC1 50514 4 3 36
GSE46452 DEC1 50514 6 13 40
GSE47630 DEC1 50514 3 16 21
GSE54993 DEC1 50514 3 3 64
GSE54994 DEC1 50514 9 11 33
GSE60625 DEC1 50514 0 0 11
GSE74703 DEC1 50514 4 3 29
GSE74704 DEC1 50514 2 7 11
TCGA DEC1 50514 28 21 47

Total number of gains: 69; Total number of losses: 97; Total Number of normals: 322.  


 

Somatic mutations of DEC1:

 

Generating mutation plots.

 

Highly correlated genes for DEC1:

 

Showing top 20/188 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
DEC1MYBPH0.668518403
DEC1HAO10.667776303
DEC1IL18BP0.658673303
DEC1KSR10.657317303
DEC1SLN0.654797303
DEC1KRTAP5-80.654339404
DEC1ADD20.645334303
DEC1TNN0.645328303
DEC1SAMD140.63368303
DEC1ATP4B0.631143303
DEC1HAP10.630994403
DEC1OR6A20.630411504
DEC1OR1A10.623295404
DEC1ZMAT40.622464404
DEC1CASR0.621972404
DEC1INE10.61984403
DEC1SIGLEC70.619804303
DEC1SLC24A20.613673504
DEC1PTCH20.611809404
DEC1GLP1R0.611007403

For details and further investigation, click here