| Full name: hyaluronan and proteoglycan link protein 2 | Alias Symbol: BRAL1 | ||
| Type: protein-coding gene | Cytoband: 1q23.1 | ||
| Entrez ID: 60484 | HGNC ID: HGNC:17410 | Ensembl Gene: ENSG00000132702 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of HAPLN2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HAPLN2 | 60484 | 220142_at | -0.1157 | 0.7460 | |
| GSE20347 | HAPLN2 | 60484 | 220142_at | -0.0477 | 0.5719 | |
| GSE23400 | HAPLN2 | 60484 | 220142_at | -0.0689 | 0.0684 | |
| GSE26886 | HAPLN2 | 60484 | 220142_at | 0.1923 | 0.0870 | |
| GSE29001 | HAPLN2 | 60484 | 220142_at | -0.0807 | 0.6057 | |
| GSE38129 | HAPLN2 | 60484 | 220142_at | -0.2168 | 0.0014 | |
| GSE45670 | HAPLN2 | 60484 | 220142_at | 0.0279 | 0.8247 | |
| GSE53622 | HAPLN2 | 60484 | 36838 | 0.0175 | 0.7855 | |
| GSE53624 | HAPLN2 | 60484 | 36838 | 0.0268 | 0.6655 | |
| GSE63941 | HAPLN2 | 60484 | 220142_at | 0.1078 | 0.5014 | |
| GSE77861 | HAPLN2 | 60484 | 220142_at | -0.0407 | 0.8099 | |
| GSE97050 | HAPLN2 | 60484 | A_33_P3318946 | -0.2601 | 0.2300 | |
| SRP219564 | HAPLN2 | 60484 | RNAseq | -1.3131 | 0.1454 | |
| TCGA | HAPLN2 | 60484 | RNAseq | 0.1844 | 0.8063 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HAPLN2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HAPLN2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HAPLN2 | 60484 | 12 | 0 | 18 | |
| GSE20123 | HAPLN2 | 60484 | 12 | 0 | 18 | |
| GSE43470 | HAPLN2 | 60484 | 7 | 2 | 34 | |
| GSE46452 | HAPLN2 | 60484 | 2 | 1 | 56 | |
| GSE47630 | HAPLN2 | 60484 | 14 | 0 | 26 | |
| GSE54993 | HAPLN2 | 60484 | 0 | 5 | 65 | |
| GSE54994 | HAPLN2 | 60484 | 16 | 0 | 37 | |
| GSE60625 | HAPLN2 | 60484 | 0 | 0 | 11 | |
| GSE74703 | HAPLN2 | 60484 | 7 | 2 | 27 | |
| GSE74704 | HAPLN2 | 60484 | 6 | 0 | 14 | |
| TCGA | HAPLN2 | 60484 | 38 | 2 | 56 |
Total number of gains: 114; Total number of losses: 12; Total Number of normals: 362.
Somatic mutations of HAPLN2:
Generating mutation plots.
Highly correlated genes for HAPLN2:
Showing top 20/380 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HAPLN2 | TTC9B | 0.673515 | 3 | 0 | 3 |
| HAPLN2 | TCF15 | 0.659517 | 3 | 0 | 3 |
| HAPLN2 | PGC | 0.640612 | 4 | 0 | 3 |
| HAPLN2 | RASL10B | 0.64019 | 4 | 0 | 3 |
| HAPLN2 | ADM2 | 0.635294 | 8 | 0 | 5 |
| HAPLN2 | LIPF | 0.63266 | 4 | 0 | 4 |
| HAPLN2 | SPRED3 | 0.629977 | 4 | 0 | 4 |
| HAPLN2 | HYAL3 | 0.629179 | 3 | 0 | 3 |
| HAPLN2 | SOX3 | 0.626272 | 5 | 0 | 5 |
| HAPLN2 | PI16 | 0.625482 | 3 | 0 | 3 |
| HAPLN2 | TRPV5 | 0.624511 | 6 | 0 | 4 |
| HAPLN2 | ZNF683 | 0.62383 | 3 | 0 | 3 |
| HAPLN2 | ADAMTSL5 | 0.62304 | 3 | 0 | 3 |
| HAPLN2 | ARID5A | 0.621792 | 3 | 0 | 3 |
| HAPLN2 | SRL | 0.616114 | 3 | 0 | 3 |
| HAPLN2 | NCDN | 0.614335 | 3 | 0 | 3 |
| HAPLN2 | HES6 | 0.614206 | 3 | 0 | 3 |
| HAPLN2 | VCX2 | 0.612553 | 4 | 0 | 4 |
| HAPLN2 | WDR93 | 0.611379 | 4 | 0 | 4 |
| HAPLN2 | GBX1 | 0.609216 | 8 | 0 | 7 |
For details and further investigation, click here
