| Full name: hyaluronidase 3 | Alias Symbol: LUCA-3|LUCA14|Minna14 | ||
| Type: protein-coding gene | Cytoband: 3p21.31 | ||
| Entrez ID: 8372 | HGNC ID: HGNC:5322 | Ensembl Gene: ENSG00000186792 | OMIM ID: 604038 |
| Drug and gene relationship at DGIdb | |||
Expression of HYAL3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HYAL3 | 8372 | 211728_s_at | 0.2247 | 0.7395 | |
| GSE20347 | HYAL3 | 8372 | 211728_s_at | -0.1296 | 0.2349 | |
| GSE23400 | HYAL3 | 8372 | 211728_s_at | -0.0630 | 0.1028 | |
| GSE26886 | HYAL3 | 8372 | 211728_s_at | 0.3707 | 0.0484 | |
| GSE29001 | HYAL3 | 8372 | 211728_s_at | -0.2982 | 0.0276 | |
| GSE38129 | HYAL3 | 8372 | 211728_s_at | -0.0545 | 0.6096 | |
| GSE45670 | HYAL3 | 8372 | 211728_s_at | 0.1319 | 0.3172 | |
| GSE53622 | HYAL3 | 8372 | 37172 | -0.3600 | 0.1280 | |
| GSE53624 | HYAL3 | 8372 | 68022 | 0.0638 | 0.5348 | |
| GSE63941 | HYAL3 | 8372 | 211728_s_at | 0.2382 | 0.5772 | |
| GSE77861 | HYAL3 | 8372 | 211728_s_at | -0.0966 | 0.5614 | |
| GSE97050 | HYAL3 | 8372 | A_33_P3273624 | 0.3347 | 0.3408 | |
| SRP007169 | HYAL3 | 8372 | RNAseq | 0.0487 | 0.9498 | |
| SRP064894 | HYAL3 | 8372 | RNAseq | 0.4901 | 0.1103 | |
| SRP133303 | HYAL3 | 8372 | RNAseq | -0.0488 | 0.8320 | |
| SRP159526 | HYAL3 | 8372 | RNAseq | -0.0055 | 0.9924 | |
| SRP193095 | HYAL3 | 8372 | RNAseq | -0.2650 | 0.0822 | |
| SRP219564 | HYAL3 | 8372 | RNAseq | -0.2370 | 0.6355 | |
| TCGA | HYAL3 | 8372 | RNAseq | 0.1017 | 0.4055 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HYAL3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HYAL3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HYAL3 | 8372 | 0 | 18 | 12 | |
| GSE20123 | HYAL3 | 8372 | 0 | 19 | 11 | |
| GSE43470 | HYAL3 | 8372 | 0 | 19 | 24 | |
| GSE46452 | HYAL3 | 8372 | 2 | 16 | 41 | |
| GSE47630 | HYAL3 | 8372 | 1 | 24 | 15 | |
| GSE54993 | HYAL3 | 8372 | 6 | 2 | 62 | |
| GSE54994 | HYAL3 | 8372 | 1 | 33 | 19 | |
| GSE60625 | HYAL3 | 8372 | 5 | 0 | 6 | |
| GSE74703 | HYAL3 | 8372 | 0 | 15 | 21 | |
| GSE74704 | HYAL3 | 8372 | 0 | 12 | 8 | |
| TCGA | HYAL3 | 8372 | 0 | 78 | 18 |
Total number of gains: 15; Total number of losses: 236; Total Number of normals: 237.
Somatic mutations of HYAL3:
Generating mutation plots.
Highly correlated genes for HYAL3:
Showing top 20/143 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HYAL3 | CORO7 | 0.747724 | 3 | 0 | 3 |
| HYAL3 | BAIAP2L2 | 0.679429 | 4 | 0 | 4 |
| HYAL3 | FOSL1 | 0.669992 | 3 | 0 | 3 |
| HYAL3 | CHIA | 0.65467 | 4 | 0 | 3 |
| HYAL3 | ELMOD3 | 0.644607 | 4 | 0 | 4 |
| HYAL3 | KLF16 | 0.633694 | 5 | 0 | 4 |
| HYAL3 | SLC6A2 | 0.631779 | 5 | 0 | 4 |
| HYAL3 | HAPLN2 | 0.629179 | 3 | 0 | 3 |
| HYAL3 | MAPK8IP3 | 0.624062 | 3 | 0 | 3 |
| HYAL3 | SPX | 0.621882 | 4 | 0 | 4 |
| HYAL3 | ATF5 | 0.61329 | 3 | 0 | 3 |
| HYAL3 | MAST1 | 0.610045 | 4 | 0 | 3 |
| HYAL3 | AUP1 | 0.609684 | 3 | 0 | 3 |
| HYAL3 | MAP6D1 | 0.609416 | 5 | 0 | 4 |
| HYAL3 | MYPOP | 0.607485 | 3 | 0 | 3 |
| HYAL3 | GAK | 0.606649 | 4 | 0 | 3 |
| HYAL3 | CORO1B | 0.605949 | 4 | 0 | 4 |
| HYAL3 | SLC9A3R2 | 0.604487 | 4 | 0 | 3 |
| HYAL3 | PYDC1 | 0.603748 | 3 | 0 | 3 |
| HYAL3 | TREM2 | 0.603483 | 4 | 0 | 3 |
For details and further investigation, click here
