| Full name: AT-rich interaction domain 5A | Alias Symbol: MRF-1|RP11-363D14 | ||
| Type: protein-coding gene | Cytoband: 2q11.2 | ||
| Entrez ID: 10865 | HGNC ID: HGNC:17361 | Ensembl Gene: ENSG00000196843 | OMIM ID: 611583 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ARID5A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARID5A | 10865 | 213138_at | -0.0913 | 0.8955 | |
| GSE20347 | ARID5A | 10865 | 213138_at | 0.5063 | 0.0000 | |
| GSE23400 | ARID5A | 10865 | 213138_at | -0.0497 | 0.5735 | |
| GSE26886 | ARID5A | 10865 | 213138_at | 0.9479 | 0.0000 | |
| GSE29001 | ARID5A | 10865 | 213138_at | 0.3472 | 0.0101 | |
| GSE38129 | ARID5A | 10865 | 213138_at | 0.1359 | 0.5308 | |
| GSE45670 | ARID5A | 10865 | 213138_at | -0.2735 | 0.0639 | |
| GSE53622 | ARID5A | 10865 | 52484 | -2.0989 | 0.0000 | |
| GSE53624 | ARID5A | 10865 | 52484 | -2.2368 | 0.0000 | |
| GSE63941 | ARID5A | 10865 | 213138_at | -0.2984 | 0.3340 | |
| GSE77861 | ARID5A | 10865 | 213138_at | 0.4430 | 0.0141 | |
| GSE97050 | ARID5A | 10865 | A_33_P3389342 | -0.6342 | 0.2151 | |
| SRP007169 | ARID5A | 10865 | RNAseq | 2.1471 | 0.0001 | |
| SRP008496 | ARID5A | 10865 | RNAseq | 1.9472 | 0.0000 | |
| SRP064894 | ARID5A | 10865 | RNAseq | -0.1212 | 0.7565 | |
| SRP133303 | ARID5A | 10865 | RNAseq | 0.0909 | 0.7700 | |
| SRP159526 | ARID5A | 10865 | RNAseq | 0.1164 | 0.8415 | |
| SRP193095 | ARID5A | 10865 | RNAseq | 1.3535 | 0.0000 | |
| TCGA | ARID5A | 10865 | RNAseq | -0.2358 | 0.0088 |
Upregulated datasets: 3; Downregulated datasets: 2.
Survival by ARID5A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARID5A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARID5A | 10865 | 6 | 2 | 22 | |
| GSE20123 | ARID5A | 10865 | 6 | 2 | 22 | |
| GSE43470 | ARID5A | 10865 | 2 | 3 | 38 | |
| GSE46452 | ARID5A | 10865 | 2 | 3 | 54 | |
| GSE47630 | ARID5A | 10865 | 7 | 0 | 33 | |
| GSE54993 | ARID5A | 10865 | 0 | 6 | 64 | |
| GSE54994 | ARID5A | 10865 | 11 | 0 | 42 | |
| GSE60625 | ARID5A | 10865 | 0 | 3 | 8 | |
| GSE74703 | ARID5A | 10865 | 2 | 2 | 32 | |
| GSE74704 | ARID5A | 10865 | 4 | 1 | 15 | |
| TCGA | ARID5A | 10865 | 36 | 3 | 57 |
Total number of gains: 76; Total number of losses: 25; Total Number of normals: 387.
Somatic mutations of ARID5A:
Generating mutation plots.
Highly correlated genes for ARID5A:
Showing top 20/308 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARID5A | APOA1 | 0.922618 | 3 | 0 | 3 |
| ARID5A | IQCF1 | 0.898183 | 3 | 0 | 3 |
| ARID5A | KLKB1 | 0.891949 | 3 | 0 | 3 |
| ARID5A | FAM163B | 0.877638 | 3 | 0 | 3 |
| ARID5A | NCCRP1 | 0.86189 | 3 | 0 | 3 |
| ARID5A | SFRP5 | 0.848836 | 3 | 0 | 3 |
| ARID5A | GPX6 | 0.843779 | 3 | 0 | 3 |
| ARID5A | KRTAP20-1 | 0.838838 | 3 | 0 | 3 |
| ARID5A | MUC22 | 0.831672 | 3 | 0 | 3 |
| ARID5A | KPRP | 0.830046 | 3 | 0 | 3 |
| ARID5A | NANOS2 | 0.826216 | 3 | 0 | 3 |
| ARID5A | MYZAP | 0.825051 | 3 | 0 | 3 |
| ARID5A | OR2Z1 | 0.819473 | 3 | 0 | 3 |
| ARID5A | TMPRSS11A | 0.801949 | 3 | 0 | 3 |
| ARID5A | OTOP3 | 0.799098 | 3 | 0 | 3 |
| ARID5A | OTOF | 0.795976 | 4 | 0 | 4 |
| ARID5A | MFSD2B | 0.78624 | 3 | 0 | 3 |
| ARID5A | ACSM1 | 0.785742 | 4 | 0 | 4 |
| ARID5A | GALNT9 | 0.779864 | 3 | 0 | 3 |
| ARID5A | PLEKHN1 | 0.779125 | 3 | 0 | 3 |
For details and further investigation, click here
