| Full name: hemoglobin subunit delta | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11p15.4 | ||
| Entrez ID: 3045 | HGNC ID: HGNC:4829 | Ensembl Gene: ENSG00000223609 | OMIM ID: 142000 |
| Drug and gene relationship at DGIdb | |||
Expression of HBD:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HBD | 3045 | 206834_at | -0.0296 | 0.9392 | |
| GSE20347 | HBD | 3045 | 206834_at | -0.1738 | 0.0586 | |
| GSE23400 | HBD | 3045 | 206834_at | -0.1329 | 0.0039 | |
| GSE26886 | HBD | 3045 | 206834_at | 0.0072 | 0.9674 | |
| GSE29001 | HBD | 3045 | 206834_at | -0.2501 | 0.0657 | |
| GSE38129 | HBD | 3045 | 206834_at | -0.3511 | 0.0007 | |
| GSE45670 | HBD | 3045 | 206834_at | -0.1182 | 0.4696 | |
| GSE53622 | HBD | 3045 | 60120 | -1.7748 | 0.0000 | |
| GSE53624 | HBD | 3045 | 60120 | -1.5852 | 0.0000 | |
| GSE63941 | HBD | 3045 | 206834_at | -0.7379 | 0.0005 | |
| GSE77861 | HBD | 3045 | 206834_at | 0.0775 | 0.6253 | |
| GSE97050 | HBD | 3045 | A_24_P75190 | -1.2020 | 0.1496 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by HBD expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HBD:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HBD | 3045 | 1 | 11 | 18 | |
| GSE20123 | HBD | 3045 | 1 | 11 | 18 | |
| GSE43470 | HBD | 3045 | 1 | 8 | 34 | |
| GSE46452 | HBD | 3045 | 7 | 8 | 44 | |
| GSE47630 | HBD | 3045 | 3 | 13 | 24 | |
| GSE54993 | HBD | 3045 | 3 | 1 | 66 | |
| GSE54994 | HBD | 3045 | 2 | 12 | 39 | |
| GSE60625 | HBD | 3045 | 0 | 0 | 11 | |
| GSE74703 | HBD | 3045 | 1 | 6 | 29 | |
| GSE74704 | HBD | 3045 | 0 | 8 | 12 | |
| TCGA | HBD | 3045 | 8 | 39 | 49 |
Total number of gains: 27; Total number of losses: 117; Total Number of normals: 344.
Somatic mutations of HBD:
Generating mutation plots.
Highly correlated genes for HBD:
Showing top 20/460 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HBD | HBA2 | 0.941017 | 3 | 0 | 3 |
| HBD | SCARB2 | 0.736736 | 3 | 0 | 3 |
| HBD | ANTXR2 | 0.71661 | 3 | 0 | 3 |
| HBD | TMTC1 | 0.715225 | 3 | 0 | 3 |
| HBD | DOK6 | 0.701888 | 3 | 0 | 3 |
| HBD | CALD1 | 0.700553 | 3 | 0 | 3 |
| HBD | CYP21A2 | 0.697111 | 3 | 0 | 3 |
| HBD | DCN | 0.689665 | 4 | 0 | 3 |
| HBD | LGALS13 | 0.685947 | 3 | 0 | 3 |
| HBD | SSTR4 | 0.680627 | 3 | 0 | 3 |
| HBD | HEPH | 0.679886 | 3 | 0 | 3 |
| HBD | COL15A1 | 0.678945 | 3 | 0 | 3 |
| HBD | CLEC3B | 0.678494 | 3 | 0 | 3 |
| HBD | OR2H2 | 0.677171 | 3 | 0 | 3 |
| HBD | NEGR1 | 0.675595 | 4 | 0 | 4 |
| HBD | ZNF382 | 0.673344 | 3 | 0 | 3 |
| HBD | S100G | 0.668407 | 4 | 0 | 4 |
| HBD | ZNF521 | 0.668205 | 3 | 0 | 3 |
| HBD | ABCB8 | 0.664676 | 3 | 0 | 3 |
| HBD | BICC1 | 0.664613 | 4 | 0 | 3 |
For details and further investigation, click here
