| Full name: scavenger receptor class B member 2 | Alias Symbol: HLGP85|LIMPII|SR-BII|LIMP-2 | ||
| Type: protein-coding gene | Cytoband: 4q21.1 | ||
| Entrez ID: 950 | HGNC ID: HGNC:1665 | Ensembl Gene: ENSG00000138760 | OMIM ID: 602257 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SCARB2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SCARB2 | 950 | 224983_at | -0.2410 | 0.5204 | |
| GSE20347 | SCARB2 | 950 | 201646_at | -0.1342 | 0.5645 | |
| GSE23400 | SCARB2 | 950 | 215754_at | 0.0336 | 0.4561 | |
| GSE26886 | SCARB2 | 950 | 224983_at | 0.3070 | 0.2996 | |
| GSE29001 | SCARB2 | 950 | 215754_at | 0.0103 | 0.9723 | |
| GSE38129 | SCARB2 | 950 | 201646_at | 0.0368 | 0.9052 | |
| GSE45670 | SCARB2 | 950 | 224983_at | -0.3435 | 0.0223 | |
| GSE53622 | SCARB2 | 950 | 67918 | 0.0440 | 0.6040 | |
| GSE53624 | SCARB2 | 950 | 67918 | 0.0867 | 0.1145 | |
| GSE63941 | SCARB2 | 950 | 224983_at | -2.5371 | 0.0003 | |
| GSE77861 | SCARB2 | 950 | 224983_at | 0.1629 | 0.5917 | |
| GSE97050 | SCARB2 | 950 | A_33_P3410459 | -0.2851 | 0.2752 | |
| SRP007169 | SCARB2 | 950 | RNAseq | 0.0561 | 0.8818 | |
| SRP008496 | SCARB2 | 950 | RNAseq | 0.5433 | 0.0412 | |
| SRP064894 | SCARB2 | 950 | RNAseq | 0.4445 | 0.0167 | |
| SRP133303 | SCARB2 | 950 | RNAseq | 0.4990 | 0.0140 | |
| SRP159526 | SCARB2 | 950 | RNAseq | 0.1136 | 0.6205 | |
| SRP193095 | SCARB2 | 950 | RNAseq | 0.1156 | 0.4439 | |
| SRP219564 | SCARB2 | 950 | RNAseq | 0.3240 | 0.3469 | |
| TCGA | SCARB2 | 950 | RNAseq | -0.1556 | 0.0003 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SCARB2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SCARB2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SCARB2 | 950 | 2 | 9 | 19 | |
| GSE20123 | SCARB2 | 950 | 2 | 9 | 19 | |
| GSE43470 | SCARB2 | 950 | 0 | 13 | 30 | |
| GSE46452 | SCARB2 | 950 | 1 | 36 | 22 | |
| GSE47630 | SCARB2 | 950 | 1 | 19 | 20 | |
| GSE54993 | SCARB2 | 950 | 7 | 0 | 63 | |
| GSE54994 | SCARB2 | 950 | 0 | 9 | 44 | |
| GSE60625 | SCARB2 | 950 | 0 | 0 | 11 | |
| GSE74703 | SCARB2 | 950 | 0 | 11 | 25 | |
| GSE74704 | SCARB2 | 950 | 2 | 5 | 13 | |
| TCGA | SCARB2 | 950 | 17 | 30 | 49 |
Total number of gains: 32; Total number of losses: 141; Total Number of normals: 315.
Somatic mutations of SCARB2:
Generating mutation plots.
Highly correlated genes for SCARB2:
Showing top 20/619 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SCARB2 | ZNF382 | 0.843859 | 3 | 0 | 3 |
| SCARB2 | CLASP1 | 0.755008 | 3 | 0 | 3 |
| SCARB2 | NKAPL | 0.753313 | 3 | 0 | 3 |
| SCARB2 | DNM3OS | 0.749315 | 3 | 0 | 3 |
| SCARB2 | RORA | 0.749005 | 3 | 0 | 3 |
| SCARB2 | MEIS1 | 0.746104 | 3 | 0 | 3 |
| SCARB2 | YPEL2 | 0.745769 | 3 | 0 | 3 |
| SCARB2 | LINC01279 | 0.745419 | 3 | 0 | 3 |
| SCARB2 | FIBIN | 0.741922 | 4 | 0 | 4 |
| SCARB2 | HBD | 0.736736 | 3 | 0 | 3 |
| SCARB2 | TEAD1 | 0.73594 | 3 | 0 | 3 |
| SCARB2 | ZNF347 | 0.735482 | 3 | 0 | 3 |
| SCARB2 | LAPTM4A | 0.731569 | 3 | 0 | 3 |
| SCARB2 | RBM18 | 0.718355 | 3 | 0 | 3 |
| SCARB2 | ARHGEF33 | 0.715203 | 3 | 0 | 3 |
| SCARB2 | AK3 | 0.713981 | 3 | 0 | 3 |
| SCARB2 | GNAQ | 0.71306 | 3 | 0 | 3 |
| SCARB2 | SLC17A5 | 0.711654 | 3 | 0 | 3 |
| SCARB2 | BNC2 | 0.709513 | 5 | 0 | 4 |
| SCARB2 | KDSR | 0.709083 | 3 | 0 | 3 |
For details and further investigation, click here
