| Full name: hemoglobin subunit alpha 2 | Alias Symbol: HBA-T2 | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 3040 | HGNC ID: HGNC:4824 | Ensembl Gene: ENSG00000188536 | OMIM ID: 141850 |
| Drug and gene relationship at DGIdb | |||
Expression of HBA2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | HBA2 | 3040 | 111214 | -1.3329 | 0.0000 | |
| GSE53624 | HBA2 | 3040 | 111214 | -1.0606 | 0.0000 | |
| GSE97050 | HBA2 | 3040 | A_23_P26457 | -0.8788 | 0.2905 | |
| SRP007169 | HBA2 | 3040 | RNAseq | 0.1838 | 0.7283 | |
| SRP064894 | HBA2 | 3040 | RNAseq | -1.4993 | 0.0051 | |
| SRP133303 | HBA2 | 3040 | RNAseq | -1.6159 | 0.0115 | |
| SRP159526 | HBA2 | 3040 | RNAseq | -3.2643 | 0.0031 | |
| SRP193095 | HBA2 | 3040 | RNAseq | 0.2945 | 0.4694 | |
| SRP219564 | HBA2 | 3040 | RNAseq | 0.2628 | 0.8386 | |
| TCGA | HBA2 | 3040 | RNAseq | -0.8947 | 0.0010 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by HBA2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HBA2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HBA2 | 3040 | 5 | 5 | 20 | |
| GSE20123 | HBA2 | 3040 | 5 | 4 | 21 | |
| GSE43470 | HBA2 | 3040 | 3 | 7 | 33 | |
| GSE46452 | HBA2 | 3040 | 38 | 1 | 20 | |
| GSE47630 | HBA2 | 3040 | 13 | 6 | 21 | |
| GSE54993 | HBA2 | 3040 | 3 | 5 | 62 | |
| GSE54994 | HBA2 | 3040 | 4 | 10 | 39 | |
| GSE60625 | HBA2 | 3040 | 4 | 0 | 7 | |
| GSE74703 | HBA2 | 3040 | 3 | 5 | 28 | |
| GSE74704 | HBA2 | 3040 | 3 | 2 | 15 | |
| TCGA | HBA2 | 3040 | 20 | 15 | 61 |
Total number of gains: 101; Total number of losses: 60; Total Number of normals: 327.
Somatic mutations of HBA2:
Generating mutation plots.
Highly correlated genes for HBA2:
Showing all 19 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HBA2 | HBD | 0.941017 | 3 | 0 | 3 |
| HBA2 | HBB | 0.894453 | 4 | 0 | 4 |
| HBA2 | TPSD1 | 0.657986 | 3 | 0 | 3 |
| HBA2 | PLAC9 | 0.633353 | 3 | 0 | 3 |
| HBA2 | CYP21A2 | 0.627906 | 3 | 0 | 3 |
| HBA2 | CLEC3B | 0.619288 | 3 | 0 | 3 |
| HBA2 | EBF1 | 0.609063 | 3 | 0 | 3 |
| HBA2 | CMA1 | 0.608624 | 3 | 0 | 3 |
| HBA2 | CFD | 0.608357 | 3 | 0 | 3 |
| HBA2 | LRRN4CL | 0.59602 | 3 | 0 | 3 |
| HBA2 | GNG11 | 0.594777 | 3 | 0 | 3 |
| HBA2 | LYVE1 | 0.59329 | 3 | 0 | 3 |
| HBA2 | CYYR1 | 0.579198 | 3 | 0 | 3 |
| HBA2 | CADM3 | 0.576859 | 3 | 0 | 3 |
| HBA2 | CCL14 | 0.562919 | 3 | 0 | 3 |
| HBA2 | TIMP4 | 0.560104 | 3 | 0 | 3 |
| HBA2 | F10 | 0.55792 | 3 | 0 | 3 |
| HBA2 | TCEAL1 | 0.540129 | 3 | 0 | 3 |
| HBA2 | MYRIP | 0.532704 | 3 | 0 | 3 |
For details and further investigation, click here
