HNRNPH3

 

Full name: heterogeneous nuclear ribonucleoprotein H3 Alias Symbol: 2H9
Type: protein-coding gene Cytoband: 10q21.3
Entrez ID: 3189 HGNC ID: HGNC:5043 Ensembl Gene: ENSG00000096746 OMIM ID: 602324
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of HNRNPH3:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 HNRNPH3 3189 208990_s_at -0.1497 0.8155
GSE20347 HNRNPH3 3189 208990_s_at 0.1789 0.3425
GSE23400 HNRNPH3 3189 210588_x_at 0.5831 0.0000
GSE26886 HNRNPH3 3189 208990_s_at -0.0247 0.9440
GSE29001 HNRNPH3 3189 208990_s_at 0.3801 0.2388
GSE38129 HNRNPH3 3189 208990_s_at 0.0289 0.8759
GSE45670 HNRNPH3 3189 208990_s_at -0.3225 0.0508
GSE53622 HNRNPH3 3189 56009 0.2547 0.0000
GSE53624 HNRNPH3 3189 56009 0.4074 0.0000
GSE63941 HNRNPH3 3189 208990_s_at 0.3151 0.3618
GSE77861 HNRNPH3 3189 208990_s_at -0.0347 0.9144
GSE97050 HNRNPH3 3189 A_24_P338187 -0.0255 0.9314
SRP007169 HNRNPH3 3189 RNAseq 0.6407 0.0714
SRP008496 HNRNPH3 3189 RNAseq 0.6035 0.0026
SRP064894 HNRNPH3 3189 RNAseq -0.0003 0.9978
SRP133303 HNRNPH3 3189 RNAseq 0.3084 0.0081
SRP159526 HNRNPH3 3189 RNAseq 0.3307 0.1202
SRP193095 HNRNPH3 3189 RNAseq -0.0385 0.7717
SRP219564 HNRNPH3 3189 RNAseq 0.0140 0.9582
TCGA HNRNPH3 3189 RNAseq 0.0354 0.4198

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by HNRNPH3 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of HNRNPH3:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 HNRNPH3 3189 3 5 22
GSE20123 HNRNPH3 3189 3 4 23
GSE43470 HNRNPH3 3189 1 8 34
GSE46452 HNRNPH3 3189 0 11 48
GSE47630 HNRNPH3 3189 2 14 24
GSE54993 HNRNPH3 3189 8 0 62
GSE54994 HNRNPH3 3189 2 12 39
GSE60625 HNRNPH3 3189 0 0 11
GSE74703 HNRNPH3 3189 1 5 30
GSE74704 HNRNPH3 3189 1 2 17
TCGA HNRNPH3 3189 10 22 64

Total number of gains: 31; Total number of losses: 83; Total Number of normals: 374.  


 

Somatic mutations of HNRNPH3:

 

Generating mutation plots.

 

Highly correlated genes for HNRNPH3:

 

Showing top 20/894 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
HNRNPH3TM9SF30.826992303
HNRNPH3ICA1L0.812427303
HNRNPH3PLIN40.777327303
HNRNPH3FAM160B10.759497404
HNRNPH3CBLL10.758316404
HNRNPH3USP9X0.736625303
HNRNPH3EBF30.731461303
HNRNPH3ICK0.731408303
HNRNPH3ZNF7910.728875303
HNRNPH3LSM110.716772403
HNRNPH3TMX30.715412303
HNRNPH3INPP5A0.711576303
HNRNPH3TMEM170B0.711405303
HNRNPH3FKBP70.711388404
HNRNPH3PSMB10.708699303
HNRNPH3ANO50.706167303
HNRNPH3KIAA11430.704325404
HNRNPH3ANAPC160.703678504
HNRNPH3ZNF7040.702718303
HNRNPH3FRY0.700769403

For details and further investigation, click here