| Full name: proteasome subunit beta 1 | Alias Symbol: PMSB1|HC5 | ||
| Type: protein-coding gene | Cytoband: 6q27 | ||
| Entrez ID: 5689 | HGNC ID: HGNC:9537 | Ensembl Gene: ENSG00000008018 | OMIM ID: 602017 |
| Drug and gene relationship at DGIdb | |||
Expression of PSMB1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PSMB1 | 5689 | 214288_s_at | 0.3920 | 0.1224 | |
| GSE20347 | PSMB1 | 5689 | 214288_s_at | 0.5537 | 0.0001 | |
| GSE23400 | PSMB1 | 5689 | 214288_s_at | 0.5253 | 0.0000 | |
| GSE26886 | PSMB1 | 5689 | 214288_s_at | 0.3204 | 0.0095 | |
| GSE29001 | PSMB1 | 5689 | 214288_s_at | 0.2904 | 0.0154 | |
| GSE38129 | PSMB1 | 5689 | 214288_s_at | 0.5195 | 0.0000 | |
| GSE45670 | PSMB1 | 5689 | 214288_s_at | 0.4198 | 0.0001 | |
| GSE53622 | PSMB1 | 5689 | 165311 | 0.2936 | 0.0000 | |
| GSE53624 | PSMB1 | 5689 | 6913 | 0.6116 | 0.0000 | |
| GSE63941 | PSMB1 | 5689 | 214288_s_at | -0.0456 | 0.8698 | |
| GSE77861 | PSMB1 | 5689 | 214288_s_at | 0.6687 | 0.0036 | |
| GSE97050 | PSMB1 | 5689 | A_23_P156531 | 0.1456 | 0.4690 | |
| SRP007169 | PSMB1 | 5689 | RNAseq | 0.7065 | 0.0604 | |
| SRP008496 | PSMB1 | 5689 | RNAseq | 0.8470 | 0.0028 | |
| SRP064894 | PSMB1 | 5689 | RNAseq | 0.6832 | 0.0040 | |
| SRP133303 | PSMB1 | 5689 | RNAseq | 0.6822 | 0.0002 | |
| SRP159526 | PSMB1 | 5689 | RNAseq | 0.2994 | 0.1560 | |
| SRP193095 | PSMB1 | 5689 | RNAseq | 0.1581 | 0.2654 | |
| SRP219564 | PSMB1 | 5689 | RNAseq | 0.2109 | 0.5601 | |
| TCGA | PSMB1 | 5689 | RNAseq | 0.1661 | 0.0003 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PSMB1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PSMB1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PSMB1 | 5689 | 4 | 6 | 20 | |
| GSE20123 | PSMB1 | 5689 | 4 | 6 | 20 | |
| GSE43470 | PSMB1 | 5689 | 2 | 0 | 41 | |
| GSE46452 | PSMB1 | 5689 | 3 | 10 | 46 | |
| GSE47630 | PSMB1 | 5689 | 7 | 7 | 26 | |
| GSE54993 | PSMB1 | 5689 | 4 | 3 | 63 | |
| GSE54994 | PSMB1 | 5689 | 9 | 9 | 35 | |
| GSE60625 | PSMB1 | 5689 | 1 | 1 | 9 | |
| GSE74703 | PSMB1 | 5689 | 2 | 0 | 34 | |
| GSE74704 | PSMB1 | 5689 | 2 | 3 | 15 | |
| TCGA | PSMB1 | 5689 | 14 | 20 | 62 |
Total number of gains: 52; Total number of losses: 65; Total Number of normals: 371.
Somatic mutations of PSMB1:
Generating mutation plots.
Highly correlated genes for PSMB1:
Showing top 20/1795 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PSMB1 | HNRNPUL1 | 0.79176 | 3 | 0 | 3 |
| PSMB1 | HAS3 | 0.785156 | 3 | 0 | 3 |
| PSMB1 | DGCR2 | 0.781962 | 4 | 0 | 4 |
| PSMB1 | NPHP3 | 0.770795 | 3 | 0 | 3 |
| PSMB1 | PET117 | 0.764469 | 3 | 0 | 3 |
| PSMB1 | C12orf73 | 0.763651 | 3 | 0 | 3 |
| PSMB1 | TYW5 | 0.762316 | 4 | 0 | 4 |
| PSMB1 | CBFA2T2 | 0.757967 | 3 | 0 | 3 |
| PSMB1 | ZFHX3 | 0.751739 | 3 | 0 | 3 |
| PSMB1 | MIER2 | 0.743944 | 3 | 0 | 3 |
| PSMB1 | TRIM47 | 0.726829 | 3 | 0 | 3 |
| PSMB1 | U2SURP | 0.72579 | 9 | 0 | 8 |
| PSMB1 | ZNF579 | 0.724629 | 3 | 0 | 3 |
| PSMB1 | KBTBD6 | 0.72441 | 4 | 0 | 3 |
| PSMB1 | WDR81 | 0.723262 | 5 | 0 | 5 |
| PSMB1 | SPRED1 | 0.723058 | 4 | 0 | 3 |
| PSMB1 | NBAS | 0.722176 | 3 | 0 | 3 |
| PSMB1 | SRGN | 0.721577 | 3 | 0 | 3 |
| PSMB1 | MLLT1 | 0.721569 | 3 | 0 | 3 |
| PSMB1 | ALKBH3 | 0.717987 | 3 | 0 | 3 |
For details and further investigation, click here
