| Full name: homeobox C8 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 12q13.13 | ||
| Entrez ID: 3224 | HGNC ID: HGNC:5129 | Ensembl Gene: | OMIM ID: 142970 |
| Drug and gene relationship at DGIdb | |||
Expression of HOXC8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HOXC8 | 3224 | 221350_at | 0.1930 | 0.4383 | |
| GSE20347 | HOXC8 | 3224 | 221350_at | 0.1650 | 0.0582 | |
| GSE23400 | HOXC8 | 3224 | 221350_at | -0.0551 | 0.2438 | |
| GSE26886 | HOXC8 | 3224 | 221350_at | 0.1589 | 0.3004 | |
| GSE29001 | HOXC8 | 3224 | 221350_at | 0.0419 | 0.7810 | |
| GSE38129 | HOXC8 | 3224 | 221350_at | 0.0063 | 0.9699 | |
| GSE45670 | HOXC8 | 3224 | 221350_at | 0.1191 | 0.2713 | |
| GSE63941 | HOXC8 | 3224 | 221350_at | 0.5929 | 0.0018 | |
| GSE77861 | HOXC8 | 3224 | 221350_at | -0.0529 | 0.6749 | |
| GSE97050 | HOXC8 | 3224 | A_24_P124558 | 1.0576 | 0.0976 | |
| SRP133303 | HOXC8 | 3224 | RNAseq | 2.5545 | 0.0000 | |
| SRP159526 | HOXC8 | 3224 | RNAseq | 3.9411 | 0.0000 | |
| SRP219564 | HOXC8 | 3224 | RNAseq | 3.8688 | 0.0000 | |
| TCGA | HOXC8 | 3224 | RNAseq | 3.6079 | 0.0000 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by HOXC8 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of HOXC8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HOXC8 | 3224 | 4 | 1 | 25 | |
| GSE20123 | HOXC8 | 3224 | 4 | 1 | 25 | |
| GSE43470 | HOXC8 | 3224 | 3 | 0 | 40 | |
| GSE46452 | HOXC8 | 3224 | 7 | 1 | 51 | |
| GSE47630 | HOXC8 | 3224 | 10 | 2 | 28 | |
| GSE54993 | HOXC8 | 3224 | 0 | 5 | 65 | |
| GSE54994 | HOXC8 | 3224 | 4 | 1 | 48 | |
| GSE60625 | HOXC8 | 3224 | 0 | 0 | 11 | |
| GSE74703 | HOXC8 | 3224 | 3 | 0 | 33 | |
| GSE74704 | HOXC8 | 3224 | 3 | 1 | 16 | |
| TCGA | HOXC8 | 3224 | 15 | 11 | 70 |
Total number of gains: 53; Total number of losses: 23; Total Number of normals: 412.
Somatic mutations of HOXC8:
Generating mutation plots.
Highly correlated genes for HOXC8:
Showing top 20/506 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HOXC8 | TMEM214 | 0.743541 | 3 | 0 | 3 |
| HOXC8 | C12orf65 | 0.728585 | 3 | 0 | 3 |
| HOXC8 | SAMD1 | 0.71887 | 3 | 0 | 3 |
| HOXC8 | CDYL2 | 0.71848 | 3 | 0 | 3 |
| HOXC8 | DICER1 | 0.712845 | 3 | 0 | 3 |
| HOXC8 | G0S2 | 0.70297 | 3 | 0 | 3 |
| HOXC8 | NMB | 0.696825 | 3 | 0 | 3 |
| HOXC8 | PRKCI | 0.696606 | 3 | 0 | 3 |
| HOXC8 | NUDCD1 | 0.693012 | 3 | 0 | 3 |
| HOXC8 | USP34 | 0.691729 | 3 | 0 | 3 |
| HOXC8 | TPD52L2 | 0.686705 | 3 | 0 | 3 |
| HOXC8 | POU2F2 | 0.685031 | 4 | 0 | 3 |
| HOXC8 | SLC25A16 | 0.683991 | 4 | 0 | 4 |
| HOXC8 | FIGNL1 | 0.68051 | 3 | 0 | 3 |
| HOXC8 | TMSB10 | 0.680147 | 3 | 0 | 3 |
| HOXC8 | PMEL | 0.67012 | 3 | 0 | 3 |
| HOXC8 | KRTAP5-8 | 0.66926 | 5 | 0 | 5 |
| HOXC8 | PLEK2 | 0.6665 | 4 | 0 | 4 |
| HOXC8 | NOLC1 | 0.6654 | 3 | 0 | 3 |
| HOXC8 | CENPH | 0.663555 | 3 | 0 | 3 |
For details and further investigation, click here
