| Full name: POU class 2 homeobox 2 | Alias Symbol: OCT2 | ||
| Type: protein-coding gene | Cytoband: 19q13.2 | ||
| Entrez ID: 5452 | HGNC ID: HGNC:9213 | Ensembl Gene: ENSG00000028277 | OMIM ID: 164176 |
| Drug and gene relationship at DGIdb | |||
Expression of POU2F2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | POU2F2 | 5452 | 229750_at | -0.0272 | 0.9589 | |
| GSE20347 | POU2F2 | 5452 | 211771_s_at | -0.0988 | 0.1062 | |
| GSE23400 | POU2F2 | 5452 | 211660_at | -0.1624 | 0.0000 | |
| GSE26886 | POU2F2 | 5452 | 229750_at | 0.0818 | 0.6133 | |
| GSE29001 | POU2F2 | 5452 | 211660_at | -0.2779 | 0.0623 | |
| GSE38129 | POU2F2 | 5452 | 211660_at | -0.1541 | 0.0924 | |
| GSE45670 | POU2F2 | 5452 | 229750_at | -0.0302 | 0.7700 | |
| GSE53622 | POU2F2 | 5452 | 96901 | 0.0624 | 0.7431 | |
| GSE53624 | POU2F2 | 5452 | 57949 | 0.0958 | 0.3896 | |
| GSE63941 | POU2F2 | 5452 | 229750_at | -0.0284 | 0.8966 | |
| GSE77861 | POU2F2 | 5452 | 229750_at | -0.0814 | 0.6288 | |
| GSE97050 | POU2F2 | 5452 | A_33_P3835524 | 0.5964 | 0.2179 | |
| SRP064894 | POU2F2 | 5452 | RNAseq | 0.7974 | 0.0156 | |
| SRP133303 | POU2F2 | 5452 | RNAseq | 0.0194 | 0.9510 | |
| SRP159526 | POU2F2 | 5452 | RNAseq | -0.7226 | 0.2075 | |
| SRP193095 | POU2F2 | 5452 | RNAseq | 1.2119 | 0.0018 | |
| SRP219564 | POU2F2 | 5452 | RNAseq | -0.0606 | 0.8985 | |
| TCGA | POU2F2 | 5452 | RNAseq | 0.0451 | 0.7184 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by POU2F2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of POU2F2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | POU2F2 | 5452 | 4 | 4 | 22 | |
| GSE20123 | POU2F2 | 5452 | 4 | 3 | 23 | |
| GSE43470 | POU2F2 | 5452 | 4 | 11 | 28 | |
| GSE46452 | POU2F2 | 5452 | 47 | 1 | 11 | |
| GSE47630 | POU2F2 | 5452 | 8 | 6 | 26 | |
| GSE54993 | POU2F2 | 5452 | 17 | 4 | 49 | |
| GSE54994 | POU2F2 | 5452 | 7 | 12 | 34 | |
| GSE60625 | POU2F2 | 5452 | 9 | 0 | 2 | |
| GSE74703 | POU2F2 | 5452 | 4 | 7 | 25 | |
| GSE74704 | POU2F2 | 5452 | 4 | 1 | 15 | |
| TCGA | POU2F2 | 5452 | 14 | 15 | 67 |
Total number of gains: 122; Total number of losses: 64; Total Number of normals: 302.
Somatic mutations of POU2F2:
Generating mutation plots.
Highly correlated genes for POU2F2:
Showing top 20/703 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| POU2F2 | RBP5 | 0.764956 | 3 | 0 | 3 |
| POU2F2 | SRMS | 0.764107 | 3 | 0 | 3 |
| POU2F2 | CARD11 | 0.740333 | 3 | 0 | 3 |
| POU2F2 | PLEK | 0.737287 | 3 | 0 | 3 |
| POU2F2 | TGFB2 | 0.733774 | 3 | 0 | 3 |
| POU2F2 | DERL3 | 0.733322 | 4 | 0 | 3 |
| POU2F2 | PTPRU | 0.7314 | 4 | 0 | 3 |
| POU2F2 | PTPN7 | 0.725841 | 4 | 0 | 3 |
| POU2F2 | ETS1 | 0.722175 | 4 | 0 | 4 |
| POU2F2 | TAGAP | 0.721147 | 5 | 0 | 4 |
| POU2F2 | PREX1 | 0.717426 | 3 | 0 | 3 |
| POU2F2 | LMAN1 | 0.715526 | 3 | 0 | 3 |
| POU2F2 | FOXC2 | 0.707769 | 3 | 0 | 3 |
| POU2F2 | EGLN2 | 0.698801 | 3 | 0 | 3 |
| POU2F2 | CNTF | 0.691916 | 3 | 0 | 3 |
| POU2F2 | MAPK11 | 0.689414 | 4 | 0 | 4 |
| POU2F2 | NDUFB11 | 0.688453 | 3 | 0 | 3 |
| POU2F2 | YTHDF3-AS1 | 0.688438 | 3 | 0 | 3 |
| POU2F2 | ZNF579 | 0.687983 | 3 | 0 | 3 |
| POU2F2 | HOXC8 | 0.685031 | 4 | 0 | 3 |
For details and further investigation, click here
