| Full name: G0/G1 switch 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1q32.2 | ||
| Entrez ID: 50486 | HGNC ID: HGNC:30229 | Ensembl Gene: ENSG00000123689 | OMIM ID: 614447 |
| Drug and gene relationship at DGIdb | |||
Expression of G0S2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | G0S2 | 50486 | 213524_s_at | 0.7746 | 0.5649 | |
| GSE20347 | G0S2 | 50486 | 213524_s_at | 0.6292 | 0.0297 | |
| GSE23400 | G0S2 | 50486 | 213524_s_at | 0.3105 | 0.0165 | |
| GSE26886 | G0S2 | 50486 | 213524_s_at | 0.5411 | 0.3296 | |
| GSE29001 | G0S2 | 50486 | 213524_s_at | 0.5715 | 0.0024 | |
| GSE38129 | G0S2 | 50486 | 213524_s_at | 0.1709 | 0.6343 | |
| GSE45670 | G0S2 | 50486 | 213524_s_at | 0.2898 | 0.6220 | |
| GSE53622 | G0S2 | 50486 | 49180 | 1.7162 | 0.0000 | |
| GSE53624 | G0S2 | 50486 | 54918 | 1.0403 | 0.0000 | |
| GSE63941 | G0S2 | 50486 | 213524_s_at | -1.4981 | 0.0742 | |
| GSE77861 | G0S2 | 50486 | 213524_s_at | 0.5506 | 0.2584 | |
| GSE97050 | G0S2 | 50486 | A_23_P74609 | 0.8607 | 0.3026 | |
| SRP064894 | G0S2 | 50486 | RNAseq | 2.1759 | 0.0000 | |
| SRP133303 | G0S2 | 50486 | RNAseq | 2.5157 | 0.0000 | |
| SRP159526 | G0S2 | 50486 | RNAseq | 1.3558 | 0.0105 | |
| SRP193095 | G0S2 | 50486 | RNAseq | 3.4797 | 0.0000 | |
| SRP219564 | G0S2 | 50486 | RNAseq | 1.0377 | 0.0441 | |
| TCGA | G0S2 | 50486 | RNAseq | -0.7969 | 0.0002 |
Upregulated datasets: 7; Downregulated datasets: 0.
Survival by G0S2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of G0S2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | G0S2 | 50486 | 11 | 0 | 19 | |
| GSE20123 | G0S2 | 50486 | 10 | 0 | 20 | |
| GSE43470 | G0S2 | 50486 | 7 | 0 | 36 | |
| GSE46452 | G0S2 | 50486 | 3 | 1 | 55 | |
| GSE47630 | G0S2 | 50486 | 15 | 0 | 25 | |
| GSE54993 | G0S2 | 50486 | 0 | 6 | 64 | |
| GSE54994 | G0S2 | 50486 | 14 | 0 | 39 | |
| GSE60625 | G0S2 | 50486 | 0 | 0 | 11 | |
| GSE74703 | G0S2 | 50486 | 7 | 0 | 29 | |
| GSE74704 | G0S2 | 50486 | 4 | 0 | 16 | |
| TCGA | G0S2 | 50486 | 44 | 3 | 49 |
Total number of gains: 115; Total number of losses: 10; Total Number of normals: 363.
Somatic mutations of G0S2:
Generating mutation plots.
Highly correlated genes for G0S2:
Showing top 20/615 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| G0S2 | FOXC2 | 0.87738 | 3 | 0 | 3 |
| G0S2 | NEIL2 | 0.812942 | 3 | 0 | 3 |
| G0S2 | MGAT5 | 0.788149 | 3 | 0 | 3 |
| G0S2 | RFTN2 | 0.769201 | 3 | 0 | 3 |
| G0S2 | RNF183 | 0.747762 | 3 | 0 | 3 |
| G0S2 | SLC6A15 | 0.739715 | 3 | 0 | 3 |
| G0S2 | ZFP92 | 0.735243 | 3 | 0 | 3 |
| G0S2 | LENG8 | 0.732689 | 3 | 0 | 3 |
| G0S2 | CERK | 0.725583 | 3 | 0 | 3 |
| G0S2 | LRRC8C | 0.717864 | 3 | 0 | 3 |
| G0S2 | FAM167B | 0.711509 | 3 | 0 | 3 |
| G0S2 | KSR2 | 0.710671 | 3 | 0 | 3 |
| G0S2 | HOXC8 | 0.70297 | 3 | 0 | 3 |
| G0S2 | RAB34 | 0.696249 | 3 | 0 | 3 |
| G0S2 | GNA13 | 0.686192 | 3 | 0 | 3 |
| G0S2 | NFE4 | 0.685733 | 3 | 0 | 3 |
| G0S2 | PTPN14 | 0.685725 | 3 | 0 | 3 |
| G0S2 | NOTCH4 | 0.68561 | 3 | 0 | 3 |
| G0S2 | TMEM71 | 0.684484 | 3 | 0 | 3 |
| G0S2 | ADAM19 | 0.684462 | 4 | 0 | 3 |
For details and further investigation, click here
