| Full name: neuromedin B | Alias Symbol: MGC2277|MGC3936|MGC17211 | ||
| Type: protein-coding gene | Cytoband: 15q25.2 | ||
| Entrez ID: 4828 | HGNC ID: HGNC:7842 | Ensembl Gene: ENSG00000197696 | OMIM ID: 162340 |
| Drug and gene relationship at DGIdb | |||
Expression of NMB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NMB | 4828 | 205204_at | 1.0702 | 0.0892 | |
| GSE20347 | NMB | 4828 | 205204_at | 0.9789 | 0.0017 | |
| GSE23400 | NMB | 4828 | 205204_at | 0.3594 | 0.0005 | |
| GSE26886 | NMB | 4828 | 205204_at | 1.3642 | 0.0002 | |
| GSE29001 | NMB | 4828 | 205204_at | 0.3910 | 0.1487 | |
| GSE38129 | NMB | 4828 | 205204_at | 1.1796 | 0.0000 | |
| GSE45670 | NMB | 4828 | 205204_at | 1.8287 | 0.0000 | |
| GSE53622 | NMB | 4828 | 85042 | 1.5377 | 0.0000 | |
| GSE53624 | NMB | 4828 | 85042 | 1.5620 | 0.0000 | |
| GSE63941 | NMB | 4828 | 205204_at | 1.0192 | 0.3923 | |
| GSE77861 | NMB | 4828 | 205204_at | 0.7503 | 0.0734 | |
| GSE97050 | NMB | 4828 | A_23_P88522 | 0.8627 | 0.1453 | |
| SRP007169 | NMB | 4828 | RNAseq | -0.6943 | 0.3516 | |
| SRP008496 | NMB | 4828 | RNAseq | -0.4032 | 0.5573 | |
| SRP064894 | NMB | 4828 | RNAseq | 2.0125 | 0.0000 | |
| SRP133303 | NMB | 4828 | RNAseq | 1.1597 | 0.0212 | |
| SRP159526 | NMB | 4828 | RNAseq | 2.9407 | 0.0000 | |
| SRP193095 | NMB | 4828 | RNAseq | 2.0658 | 0.0000 | |
| SRP219564 | NMB | 4828 | RNAseq | 1.5165 | 0.0159 | |
| TCGA | NMB | 4828 | RNAseq | 0.8850 | 0.0000 |
Upregulated datasets: 10; Downregulated datasets: 0.
Survival by NMB expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NMB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NMB | 4828 | 8 | 0 | 22 | |
| GSE20123 | NMB | 4828 | 8 | 0 | 22 | |
| GSE43470 | NMB | 4828 | 4 | 4 | 35 | |
| GSE46452 | NMB | 4828 | 3 | 7 | 49 | |
| GSE47630 | NMB | 4828 | 8 | 10 | 22 | |
| GSE54993 | NMB | 4828 | 5 | 6 | 59 | |
| GSE54994 | NMB | 4828 | 6 | 6 | 41 | |
| GSE60625 | NMB | 4828 | 4 | 0 | 7 | |
| GSE74703 | NMB | 4828 | 4 | 2 | 30 | |
| GSE74704 | NMB | 4828 | 4 | 0 | 16 | |
| TCGA | NMB | 4828 | 16 | 13 | 67 |
Total number of gains: 70; Total number of losses: 48; Total Number of normals: 370.
Somatic mutations of NMB:
Generating mutation plots.
Highly correlated genes for NMB:
Showing top 20/1588 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NMB | CDCA2 | 0.75914 | 4 | 0 | 4 |
| NMB | FAM20C | 0.754803 | 3 | 0 | 3 |
| NMB | WDR66 | 0.74396 | 7 | 0 | 7 |
| NMB | FAM89A | 0.736973 | 3 | 0 | 3 |
| NMB | XPR1 | 0.731268 | 7 | 0 | 7 |
| NMB | NLN | 0.730722 | 3 | 0 | 3 |
| NMB | ANLN | 0.724729 | 6 | 0 | 6 |
| NMB | CD276 | 0.723803 | 4 | 0 | 4 |
| NMB | SLC39A3 | 0.714969 | 3 | 0 | 3 |
| NMB | CRTC2 | 0.713824 | 3 | 0 | 3 |
| NMB | UBE2T | 0.709277 | 7 | 0 | 7 |
| NMB | CENPO | 0.703188 | 4 | 0 | 4 |
| NMB | PYCR2 | 0.701989 | 3 | 0 | 3 |
| NMB | BOLA3 | 0.700703 | 7 | 0 | 6 |
| NMB | RAVER1 | 0.698329 | 3 | 0 | 3 |
| NMB | HOXC8 | 0.696825 | 3 | 0 | 3 |
| NMB | WDR54 | 0.696646 | 7 | 0 | 7 |
| NMB | SHANK3 | 0.695745 | 3 | 0 | 3 |
| NMB | TTL | 0.69414 | 7 | 0 | 7 |
| NMB | FSCN1 | 0.693889 | 11 | 0 | 9 |
For details and further investigation, click here
