| Full name: nucleolar and coiled-body phosphoprotein 1 | Alias Symbol: P130|KIAA0035|NOPP140|NOPP130 | ||
| Type: protein-coding gene | Cytoband: 10q24.32 | ||
| Entrez ID: 9221 | HGNC ID: HGNC:15608 | Ensembl Gene: ENSG00000166197 | OMIM ID: 602394 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of NOLC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NOLC1 | 9221 | 211951_at | 0.5767 | 0.0736 | |
| GSE20347 | NOLC1 | 9221 | 211951_at | 0.4473 | 0.0031 | |
| GSE23400 | NOLC1 | 9221 | 211951_at | 0.4596 | 0.0000 | |
| GSE26886 | NOLC1 | 9221 | 211951_at | 0.5786 | 0.0120 | |
| GSE29001 | NOLC1 | 9221 | 211951_at | 0.4903 | 0.0513 | |
| GSE38129 | NOLC1 | 9221 | 211951_at | 0.5257 | 0.0001 | |
| GSE45670 | NOLC1 | 9221 | 211951_at | 0.2757 | 0.1042 | |
| GSE53622 | NOLC1 | 9221 | 79149 | 0.4273 | 0.0000 | |
| GSE53624 | NOLC1 | 9221 | 79149 | 0.6028 | 0.0000 | |
| GSE63941 | NOLC1 | 9221 | 211951_at | 0.9030 | 0.0045 | |
| GSE77861 | NOLC1 | 9221 | 211951_at | 0.4320 | 0.2130 | |
| GSE97050 | NOLC1 | 9221 | A_23_P202143 | 0.4815 | 0.1555 | |
| SRP007169 | NOLC1 | 9221 | RNAseq | 1.3697 | 0.0006 | |
| SRP008496 | NOLC1 | 9221 | RNAseq | 1.1949 | 0.0000 | |
| SRP064894 | NOLC1 | 9221 | RNAseq | 0.0873 | 0.6626 | |
| SRP133303 | NOLC1 | 9221 | RNAseq | 0.6605 | 0.0000 | |
| SRP159526 | NOLC1 | 9221 | RNAseq | 0.1949 | 0.5783 | |
| SRP193095 | NOLC1 | 9221 | RNAseq | 0.7067 | 0.0000 | |
| SRP219564 | NOLC1 | 9221 | RNAseq | 0.5126 | 0.2173 | |
| TCGA | NOLC1 | 9221 | RNAseq | 0.1514 | 0.0009 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by NOLC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NOLC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NOLC1 | 9221 | 2 | 9 | 19 | |
| GSE20123 | NOLC1 | 9221 | 2 | 8 | 20 | |
| GSE43470 | NOLC1 | 9221 | 0 | 8 | 35 | |
| GSE46452 | NOLC1 | 9221 | 0 | 11 | 48 | |
| GSE47630 | NOLC1 | 9221 | 2 | 14 | 24 | |
| GSE54993 | NOLC1 | 9221 | 8 | 0 | 62 | |
| GSE54994 | NOLC1 | 9221 | 1 | 12 | 40 | |
| GSE60625 | NOLC1 | 9221 | 0 | 0 | 11 | |
| GSE74703 | NOLC1 | 9221 | 0 | 5 | 31 | |
| GSE74704 | NOLC1 | 9221 | 1 | 4 | 15 | |
| TCGA | NOLC1 | 9221 | 5 | 29 | 62 |
Total number of gains: 21; Total number of losses: 100; Total Number of normals: 367.
Somatic mutations of NOLC1:
Generating mutation plots.
Highly correlated genes for NOLC1:
Showing top 20/1528 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NOLC1 | UHRF1BP1 | 0.86022 | 3 | 0 | 3 |
| NOLC1 | SMARCAD1 | 0.822154 | 3 | 0 | 3 |
| NOLC1 | ZNF354B | 0.814903 | 3 | 0 | 3 |
| NOLC1 | ALG1 | 0.814486 | 3 | 0 | 3 |
| NOLC1 | PET117 | 0.810669 | 3 | 0 | 3 |
| NOLC1 | CPNE8 | 0.799207 | 3 | 0 | 3 |
| NOLC1 | FH | 0.773779 | 3 | 0 | 3 |
| NOLC1 | MGAT4B | 0.771289 | 3 | 0 | 3 |
| NOLC1 | ZDHHC4 | 0.755356 | 3 | 0 | 3 |
| NOLC1 | NUP188 | 0.740864 | 3 | 0 | 3 |
| NOLC1 | DDX21 | 0.739312 | 12 | 0 | 12 |
| NOLC1 | FAM161A | 0.73857 | 4 | 0 | 3 |
| NOLC1 | ANAPC4 | 0.737829 | 3 | 0 | 3 |
| NOLC1 | GNPTAB | 0.73774 | 3 | 0 | 3 |
| NOLC1 | TUBGCP3 | 0.737092 | 3 | 0 | 3 |
| NOLC1 | ANKRD10 | 0.734971 | 3 | 0 | 3 |
| NOLC1 | CPT1A | 0.730082 | 3 | 0 | 3 |
| NOLC1 | INTS10 | 0.729379 | 4 | 0 | 3 |
| NOLC1 | FARS2 | 0.728241 | 4 | 0 | 3 |
| NOLC1 | DHRS13 | 0.723779 | 3 | 0 | 3 |
For details and further investigation, click here
