| Full name: homeobox D8 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2q31.1 | ||
| Entrez ID: 3234 | HGNC ID: HGNC:5139 | Ensembl Gene: ENSG00000175879 | OMIM ID: 142985 |
| Drug and gene relationship at DGIdb | |||
Expression of HOXD8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HOXD8 | 3234 | 231906_at | 1.0574 | 0.0571 | |
| GSE26886 | HOXD8 | 3234 | 231906_at | 1.4057 | 0.0003 | |
| GSE45670 | HOXD8 | 3234 | 231906_at | 0.6536 | 0.0688 | |
| GSE53622 | HOXD8 | 3234 | 26421 | 1.1085 | 0.0000 | |
| GSE53624 | HOXD8 | 3234 | 26421 | 1.3012 | 0.0000 | |
| GSE63941 | HOXD8 | 3234 | 231906_at | 1.8944 | 0.0231 | |
| GSE77861 | HOXD8 | 3234 | 231906_at | 0.4252 | 0.1799 | |
| GSE97050 | HOXD8 | 3234 | A_23_P210164 | 0.8476 | 0.1313 | |
| SRP007169 | HOXD8 | 3234 | RNAseq | 1.2475 | 0.0889 | |
| SRP008496 | HOXD8 | 3234 | RNAseq | 1.2714 | 0.0348 | |
| SRP064894 | HOXD8 | 3234 | RNAseq | 1.1524 | 0.0000 | |
| SRP133303 | HOXD8 | 3234 | RNAseq | 1.2912 | 0.0001 | |
| SRP159526 | HOXD8 | 3234 | RNAseq | 2.2733 | 0.0000 | |
| SRP219564 | HOXD8 | 3234 | RNAseq | 1.8249 | 0.0247 | |
| TCGA | HOXD8 | 3234 | RNAseq | 0.8880 | 0.0000 |
Upregulated datasets: 9; Downregulated datasets: 0.
Survival by HOXD8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HOXD8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HOXD8 | 3234 | 9 | 0 | 21 | |
| GSE20123 | HOXD8 | 3234 | 9 | 0 | 21 | |
| GSE43470 | HOXD8 | 3234 | 5 | 1 | 37 | |
| GSE46452 | HOXD8 | 3234 | 1 | 4 | 54 | |
| GSE47630 | HOXD8 | 3234 | 4 | 4 | 32 | |
| GSE54993 | HOXD8 | 3234 | 0 | 5 | 65 | |
| GSE54994 | HOXD8 | 3234 | 11 | 4 | 38 | |
| GSE60625 | HOXD8 | 3234 | 0 | 3 | 8 | |
| GSE74703 | HOXD8 | 3234 | 4 | 1 | 31 | |
| GSE74704 | HOXD8 | 3234 | 5 | 0 | 15 | |
| TCGA | HOXD8 | 3234 | 28 | 5 | 63 |
Total number of gains: 76; Total number of losses: 27; Total Number of normals: 385.
Somatic mutations of HOXD8:
Generating mutation plots.
Highly correlated genes for HOXD8:
Showing top 20/1276 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HOXD8 | HSD17B1 | 0.824592 | 3 | 0 | 3 |
| HOXD8 | E2F5 | 0.785083 | 3 | 0 | 3 |
| HOXD8 | TFDP2 | 0.775589 | 3 | 0 | 3 |
| HOXD8 | ZNF680 | 0.77091 | 3 | 0 | 3 |
| HOXD8 | DGKQ | 0.750333 | 3 | 0 | 3 |
| HOXD8 | LSM14B | 0.747021 | 3 | 0 | 3 |
| HOXD8 | RHBDF2 | 0.746066 | 3 | 0 | 3 |
| HOXD8 | ARHGAP9 | 0.744103 | 3 | 0 | 3 |
| HOXD8 | USP21 | 0.74008 | 3 | 0 | 3 |
| HOXD8 | CEP250 | 0.733655 | 4 | 0 | 3 |
| HOXD8 | PPP1R16A | 0.730637 | 3 | 0 | 3 |
| HOXD8 | RBM12B | 0.727925 | 3 | 0 | 3 |
| HOXD8 | TATDN2 | 0.725134 | 3 | 0 | 3 |
| HOXD8 | C17orf67 | 0.720663 | 4 | 0 | 4 |
| HOXD8 | TMEM205 | 0.720465 | 3 | 0 | 3 |
| HOXD8 | TNFRSF9 | 0.719934 | 4 | 0 | 3 |
| HOXD8 | RRP7A | 0.718803 | 4 | 0 | 4 |
| HOXD8 | HHAT | 0.712714 | 3 | 0 | 3 |
| HOXD8 | RICTOR | 0.710686 | 3 | 0 | 3 |
| HOXD8 | CMTM4 | 0.705399 | 3 | 0 | 3 |
For details and further investigation, click here
