| Full name: diacylglycerol kinase theta | Alias Symbol: DAGK|DAGK7 | ||
| Type: protein-coding gene | Cytoband: 4p16.3 | ||
| Entrez ID: 1609 | HGNC ID: HGNC:2856 | Ensembl Gene: ENSG00000145214 | OMIM ID: 601207 |
| Drug and gene relationship at DGIdb | |||
Expression of DGKQ:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DGKQ | 1609 | 226605_at | 0.6669 | 0.0786 | |
| GSE20347 | DGKQ | 1609 | 207562_at | -0.2030 | 0.0176 | |
| GSE23400 | DGKQ | 1609 | 207562_at | -0.1202 | 0.0003 | |
| GSE26886 | DGKQ | 1609 | 226605_at | 0.0570 | 0.8194 | |
| GSE29001 | DGKQ | 1609 | 207562_at | -0.1611 | 0.1937 | |
| GSE38129 | DGKQ | 1609 | 207562_at | -0.1382 | 0.0827 | |
| GSE45670 | DGKQ | 1609 | 226605_at | 0.2727 | 0.0885 | |
| GSE53622 | DGKQ | 1609 | 20087 | 0.0105 | 0.9253 | |
| GSE53624 | DGKQ | 1609 | 20087 | 0.0662 | 0.4650 | |
| GSE63941 | DGKQ | 1609 | 226605_at | -1.3691 | 0.0095 | |
| GSE77861 | DGKQ | 1609 | 226605_at | 0.3502 | 0.4109 | |
| GSE97050 | DGKQ | 1609 | A_33_P3216427 | 0.2546 | 0.3193 | |
| SRP007169 | DGKQ | 1609 | RNAseq | -0.1084 | 0.8198 | |
| SRP008496 | DGKQ | 1609 | RNAseq | -0.5705 | 0.1452 | |
| SRP064894 | DGKQ | 1609 | RNAseq | 0.3299 | 0.0271 | |
| SRP133303 | DGKQ | 1609 | RNAseq | -0.1286 | 0.4814 | |
| SRP159526 | DGKQ | 1609 | RNAseq | 0.2895 | 0.2054 | |
| SRP193095 | DGKQ | 1609 | RNAseq | -0.0010 | 0.9952 | |
| SRP219564 | DGKQ | 1609 | RNAseq | 0.3021 | 0.4884 | |
| TCGA | DGKQ | 1609 | RNAseq | -0.0661 | 0.3219 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by DGKQ expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DGKQ:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DGKQ | 1609 | 0 | 17 | 13 | |
| GSE20123 | DGKQ | 1609 | 0 | 15 | 15 | |
| GSE43470 | DGKQ | 1609 | 0 | 17 | 26 | |
| GSE46452 | DGKQ | 1609 | 1 | 36 | 22 | |
| GSE47630 | DGKQ | 1609 | 2 | 19 | 19 | |
| GSE54993 | DGKQ | 1609 | 11 | 0 | 59 | |
| GSE54994 | DGKQ | 1609 | 3 | 12 | 38 | |
| GSE60625 | DGKQ | 1609 | 0 | 0 | 11 | |
| GSE74703 | DGKQ | 1609 | 0 | 13 | 23 | |
| GSE74704 | DGKQ | 1609 | 0 | 8 | 12 | |
| TCGA | DGKQ | 1609 | 9 | 47 | 40 |
Total number of gains: 26; Total number of losses: 184; Total Number of normals: 278.
Somatic mutations of DGKQ:
Generating mutation plots.
Highly correlated genes for DGKQ:
Showing top 20/274 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DGKQ | SLC35A2 | 0.835512 | 3 | 0 | 3 |
| DGKQ | RSAD1 | 0.80047 | 3 | 0 | 3 |
| DGKQ | RNF187 | 0.783099 | 3 | 0 | 3 |
| DGKQ | PREB | 0.770518 | 3 | 0 | 3 |
| DGKQ | PPIB | 0.757994 | 3 | 0 | 3 |
| DGKQ | HOXD8 | 0.750333 | 3 | 0 | 3 |
| DGKQ | APBB1IP | 0.735507 | 3 | 0 | 3 |
| DGKQ | LTV1 | 0.730507 | 3 | 0 | 3 |
| DGKQ | PPP1R9B | 0.724281 | 4 | 0 | 3 |
| DGKQ | EIF4G1 | 0.714019 | 4 | 0 | 3 |
| DGKQ | LINGO1 | 0.710754 | 3 | 0 | 3 |
| DGKQ | NEU3 | 0.708722 | 3 | 0 | 3 |
| DGKQ | CEP250 | 0.706094 | 3 | 0 | 3 |
| DGKQ | PCCB | 0.704279 | 3 | 0 | 3 |
| DGKQ | ECE1 | 0.704233 | 3 | 0 | 3 |
| DGKQ | C3orf33 | 0.703877 | 3 | 0 | 3 |
| DGKQ | C10orf55 | 0.698439 | 3 | 0 | 3 |
| DGKQ | CASKIN2 | 0.697965 | 3 | 0 | 3 |
| DGKQ | HNRNPL | 0.696436 | 3 | 0 | 3 |
| DGKQ | TRMT1 | 0.692065 | 4 | 0 | 3 |
For details and further investigation, click here
