| Full name: rhomboid 5 homolog 2 | Alias Symbol: FLJ22341|RHBDL5|TOCG|iRhom2 | ||
| Type: protein-coding gene | Cytoband: 17q25.3 | ||
| Entrez ID: 79651 | HGNC ID: HGNC:20788 | Ensembl Gene: ENSG00000129667 | OMIM ID: 614404 |
| Drug and gene relationship at DGIdb | |||
Expression of RHBDF2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RHBDF2 | 79651 | 219202_at | 0.5942 | 0.2431 | |
| GSE20347 | RHBDF2 | 79651 | 219202_at | 0.1734 | 0.1386 | |
| GSE23400 | RHBDF2 | 79651 | 219202_at | 0.2838 | 0.0000 | |
| GSE26886 | RHBDF2 | 79651 | 219202_at | 0.6472 | 0.0006 | |
| GSE29001 | RHBDF2 | 79651 | 219202_at | 0.3273 | 0.3238 | |
| GSE38129 | RHBDF2 | 79651 | 219202_at | 0.3393 | 0.0523 | |
| GSE45670 | RHBDF2 | 79651 | 219202_at | 0.6167 | 0.0004 | |
| GSE63941 | RHBDF2 | 79651 | 219202_at | 0.8881 | 0.0057 | |
| GSE77861 | RHBDF2 | 79651 | 219202_at | 0.4824 | 0.1165 | |
| GSE97050 | RHBDF2 | 79651 | A_23_P329870 | 1.1818 | 0.0867 | |
| SRP007169 | RHBDF2 | 79651 | RNAseq | 0.1229 | 0.7630 | |
| SRP008496 | RHBDF2 | 79651 | RNAseq | -0.2795 | 0.3227 | |
| SRP064894 | RHBDF2 | 79651 | RNAseq | 0.8449 | 0.0001 | |
| SRP133303 | RHBDF2 | 79651 | RNAseq | 0.8282 | 0.0000 | |
| SRP159526 | RHBDF2 | 79651 | RNAseq | 0.0199 | 0.9516 | |
| SRP193095 | RHBDF2 | 79651 | RNAseq | 0.8601 | 0.0000 | |
| SRP219564 | RHBDF2 | 79651 | RNAseq | 0.3480 | 0.4552 | |
| TCGA | RHBDF2 | 79651 | RNAseq | 0.4552 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RHBDF2 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of RHBDF2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RHBDF2 | 79651 | 7 | 2 | 21 | |
| GSE20123 | RHBDF2 | 79651 | 7 | 2 | 21 | |
| GSE43470 | RHBDF2 | 79651 | 5 | 3 | 35 | |
| GSE46452 | RHBDF2 | 79651 | 33 | 1 | 25 | |
| GSE47630 | RHBDF2 | 79651 | 8 | 1 | 31 | |
| GSE54993 | RHBDF2 | 79651 | 2 | 5 | 63 | |
| GSE54994 | RHBDF2 | 79651 | 10 | 4 | 39 | |
| GSE60625 | RHBDF2 | 79651 | 6 | 0 | 5 | |
| GSE74703 | RHBDF2 | 79651 | 5 | 1 | 30 | |
| GSE74704 | RHBDF2 | 79651 | 5 | 1 | 14 | |
| TCGA | RHBDF2 | 79651 | 31 | 10 | 55 |
Total number of gains: 119; Total number of losses: 30; Total Number of normals: 339.
Somatic mutations of RHBDF2:
Generating mutation plots.
Highly correlated genes for RHBDF2:
Showing top 20/1179 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RHBDF2 | SLC30A7 | 0.79336 | 3 | 0 | 3 |
| RHBDF2 | C8orf76 | 0.7911 | 3 | 0 | 3 |
| RHBDF2 | TSPAN17 | 0.77219 | 3 | 0 | 3 |
| RHBDF2 | LPCAT2 | 0.768262 | 3 | 0 | 3 |
| RHBDF2 | RCC1 | 0.765555 | 4 | 0 | 4 |
| RHBDF2 | MFSD3 | 0.76413 | 3 | 0 | 3 |
| RHBDF2 | PHRF1 | 0.759575 | 3 | 0 | 3 |
| RHBDF2 | HOXD8 | 0.746066 | 3 | 0 | 3 |
| RHBDF2 | XRCC4 | 0.738751 | 3 | 0 | 3 |
| RHBDF2 | SERPINF2 | 0.738083 | 4 | 0 | 4 |
| RHBDF2 | DHX37 | 0.73498 | 4 | 0 | 4 |
| RHBDF2 | GART | 0.728391 | 5 | 0 | 5 |
| RHBDF2 | NUP43 | 0.727574 | 3 | 0 | 3 |
| RHBDF2 | ZBTB9 | 0.727147 | 4 | 0 | 4 |
| RHBDF2 | BOLA3 | 0.726957 | 3 | 0 | 3 |
| RHBDF2 | PRELID1 | 0.724616 | 3 | 0 | 3 |
| RHBDF2 | ALKBH6 | 0.721418 | 4 | 0 | 4 |
| RHBDF2 | KRTCAP2 | 0.717404 | 4 | 0 | 4 |
| RHBDF2 | PPP2R5B | 0.716022 | 4 | 0 | 4 |
| RHBDF2 | DNAJB11 | 0.713733 | 3 | 0 | 3 |
For details and further investigation, click here
