RRP7A

 

Full name: ribosomal RNA processing 7 homolog A Alias Symbol: CGI-96|Rrp7
Type: protein-coding gene Cytoband: 22q13.2
Entrez ID: 27341 HGNC ID: HGNC:24286 Ensembl Gene: ENSG00000189306 OMIM ID: 
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of RRP7A:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 RRP7A 27341 33307_at 0.7351 0.1018
GSE20347 RRP7A 27341 202937_x_at 0.4970 0.0182
GSE23400 RRP7A 27341 202937_x_at 0.3210 0.0000
GSE26886 RRP7A 27341 33307_at 0.6959 0.0304
GSE29001 RRP7A 27341 33307_at 0.3731 0.1713
GSE38129 RRP7A 27341 33307_at 0.5452 0.0002
GSE45670 RRP7A 27341 33307_at 0.4377 0.0166
GSE53622 RRP7A 27341 54140 0.8418 0.0000
GSE53624 RRP7A 27341 54140 0.8845 0.0000
GSE63941 RRP7A 27341 202937_x_at 0.7021 0.1359
GSE77861 RRP7A 27341 33307_at 0.2395 0.0331
GSE97050 RRP7A 27341 A_23_P29303 0.4945 0.1965
SRP007169 RRP7A 27341 RNAseq 0.6707 0.1287
SRP008496 RRP7A 27341 RNAseq 0.6663 0.0218
SRP064894 RRP7A 27341 RNAseq 0.7499 0.0086
SRP133303 RRP7A 27341 RNAseq 0.2157 0.2432
SRP159526 RRP7A 27341 RNAseq 0.5941 0.0390
SRP193095 RRP7A 27341 RNAseq 0.3826 0.0010
SRP219564 RRP7A 27341 RNAseq 0.4643 0.0790
TCGA RRP7A 27341 RNAseq 0.1471 0.0158

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by RRP7A expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of RRP7A:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 RRP7A 27341 6 6 18
GSE20123 RRP7A 27341 6 5 19
GSE43470 RRP7A 27341 5 6 32
GSE46452 RRP7A 27341 31 2 26
GSE47630 RRP7A 27341 9 4 27
GSE54993 RRP7A 27341 3 6 61
GSE54994 RRP7A 27341 11 8 34
GSE60625 RRP7A 27341 5 0 6
GSE74703 RRP7A 27341 5 4 27
GSE74704 RRP7A 27341 3 3 14
TCGA RRP7A 27341 28 13 55

Total number of gains: 112; Total number of losses: 57; Total Number of normals: 319.  

 

Somatic mutations of RRP7A:

 

Generating mutation plots.

 

Highly correlated genes for RRP7A:

 

Showing top 20/1613 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
RRP7AMAD2L20.744404404
RRP7AKTI120.732615303
RRP7ATRIM470.726001303
RRP7ATCIRG10.725082404
RRP7AACAP10.719424303
RRP7AC17orf670.719067303
RRP7APYCR20.718922303
RRP7AHOXD80.718803404
RRP7AEBNA1BP20.717372303
RRP7AKDM6B0.714928303
RRP7ASH2B20.710526403
RRP7ACCDC1500.707049303
RRP7APLEKHA40.706604303
RRP7ASASS60.705063404
RRP7ARHBDD20.703749404
RRP7ADHFR0.703018404
RRP7ASPNS10.702638303
RRP7ANUCKS10.702365303
RRP7ASLC35B20.701136303
RRP7ARNF1660.701089303

For details and further investigation, click here