| Full name: HCLS1 binding protein 3 | Alias Symbol: HS1-BP3|FLJ14249 | ||
| Type: protein-coding gene | Cytoband: 2p24.1 | ||
| Entrez ID: 64342 | HGNC ID: HGNC:24979 | Ensembl Gene: ENSG00000118960 | OMIM ID: 609359 |
| Drug and gene relationship at DGIdb | |||
Expression of HS1BP3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HS1BP3 | 64342 | 219020_at | 0.0013 | 0.9988 | |
| GSE20347 | HS1BP3 | 64342 | 219020_at | 0.4040 | 0.0265 | |
| GSE23400 | HS1BP3 | 64342 | 219020_at | -0.0207 | 0.7262 | |
| GSE26886 | HS1BP3 | 64342 | 219020_at | 0.7621 | 0.0000 | |
| GSE29001 | HS1BP3 | 64342 | 219020_at | 0.1086 | 0.6230 | |
| GSE38129 | HS1BP3 | 64342 | 219020_at | 0.0441 | 0.8189 | |
| GSE45670 | HS1BP3 | 64342 | 219020_at | 0.0457 | 0.8090 | |
| GSE53622 | HS1BP3 | 64342 | 425 | -0.0510 | 0.6333 | |
| GSE53624 | HS1BP3 | 64342 | 59570 | 0.3146 | 0.0000 | |
| GSE63941 | HS1BP3 | 64342 | 219020_at | 0.6259 | 0.1882 | |
| GSE77861 | HS1BP3 | 64342 | 219020_at | 0.3475 | 0.0450 | |
| GSE97050 | HS1BP3 | 64342 | A_33_P3344276 | -0.5013 | 0.3142 | |
| SRP007169 | HS1BP3 | 64342 | RNAseq | 0.1783 | 0.6702 | |
| SRP008496 | HS1BP3 | 64342 | RNAseq | 0.2264 | 0.5429 | |
| SRP064894 | HS1BP3 | 64342 | RNAseq | 0.2435 | 0.3102 | |
| SRP133303 | HS1BP3 | 64342 | RNAseq | 0.2030 | 0.2716 | |
| SRP159526 | HS1BP3 | 64342 | RNAseq | 0.6289 | 0.0912 | |
| SRP193095 | HS1BP3 | 64342 | RNAseq | 0.4813 | 0.0005 | |
| SRP219564 | HS1BP3 | 64342 | RNAseq | 0.1388 | 0.8143 | |
| TCGA | HS1BP3 | 64342 | RNAseq | -0.0975 | 0.0846 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HS1BP3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HS1BP3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HS1BP3 | 64342 | 9 | 2 | 19 | |
| GSE20123 | HS1BP3 | 64342 | 9 | 2 | 19 | |
| GSE43470 | HS1BP3 | 64342 | 2 | 0 | 41 | |
| GSE46452 | HS1BP3 | 64342 | 3 | 4 | 52 | |
| GSE47630 | HS1BP3 | 64342 | 7 | 0 | 33 | |
| GSE54993 | HS1BP3 | 64342 | 0 | 7 | 63 | |
| GSE54994 | HS1BP3 | 64342 | 11 | 0 | 42 | |
| GSE60625 | HS1BP3 | 64342 | 0 | 3 | 8 | |
| GSE74703 | HS1BP3 | 64342 | 2 | 0 | 34 | |
| GSE74704 | HS1BP3 | 64342 | 8 | 2 | 10 | |
| TCGA | HS1BP3 | 64342 | 36 | 2 | 58 |
Total number of gains: 87; Total number of losses: 22; Total Number of normals: 379.
Somatic mutations of HS1BP3:
Generating mutation plots.
Highly correlated genes for HS1BP3:
Showing top 20/409 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HS1BP3 | BLACAT1 | 0.728336 | 3 | 0 | 3 |
| HS1BP3 | THRA | 0.725176 | 5 | 0 | 5 |
| HS1BP3 | SPATA2L | 0.701871 | 3 | 0 | 3 |
| HS1BP3 | GPC1 | 0.687734 | 3 | 0 | 3 |
| HS1BP3 | IQUB | 0.68252 | 3 | 0 | 3 |
| HS1BP3 | RASD2 | 0.675322 | 4 | 0 | 3 |
| HS1BP3 | RASD1 | 0.672021 | 3 | 0 | 3 |
| HS1BP3 | SLC12A9 | 0.66869 | 4 | 0 | 4 |
| HS1BP3 | CDC42EP4 | 0.668256 | 4 | 0 | 3 |
| HS1BP3 | PTPDC1 | 0.667231 | 5 | 0 | 4 |
| HS1BP3 | CASC4 | 0.66494 | 3 | 0 | 3 |
| HS1BP3 | PPP1R35 | 0.661955 | 3 | 0 | 3 |
| HS1BP3 | KLHL13 | 0.65805 | 4 | 0 | 4 |
| HS1BP3 | PRELID2 | 0.652773 | 4 | 0 | 3 |
| HS1BP3 | HABP4 | 0.644696 | 6 | 0 | 6 |
| HS1BP3 | SQSTM1 | 0.644521 | 4 | 0 | 3 |
| HS1BP3 | ABHD1 | 0.643097 | 4 | 0 | 4 |
| HS1BP3 | CCDC136 | 0.641637 | 4 | 0 | 3 |
| HS1BP3 | ZNF703 | 0.640279 | 4 | 0 | 3 |
| HS1BP3 | TPPP3 | 0.640229 | 4 | 0 | 3 |
For details and further investigation, click here
