| Full name: heparan sulfate-glucosamine 3-sulfotransferase 6 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 64711 | HGNC ID: HGNC:14178 | Ensembl Gene: ENSG00000162040 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of HS3ST6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HS3ST6 | 64711 | 239547_at | -1.7669 | 0.0151 | |
| GSE26886 | HS3ST6 | 64711 | 239547_at | -0.4386 | 0.4104 | |
| GSE45670 | HS3ST6 | 64711 | 239547_at | -0.8330 | 0.0251 | |
| GSE53622 | HS3ST6 | 64711 | 60235 | -2.3149 | 0.0000 | |
| GSE53624 | HS3ST6 | 64711 | 60235 | -2.9550 | 0.0000 | |
| GSE63941 | HS3ST6 | 64711 | 239547_at | 0.2491 | 0.6195 | |
| GSE77861 | HS3ST6 | 64711 | 239547_at | -1.1889 | 0.0195 | |
| GSE97050 | HS3ST6 | 64711 | A_33_P3302185 | -0.4374 | 0.1450 | |
| SRP007169 | HS3ST6 | 64711 | RNAseq | -5.9688 | 0.0000 | |
| SRP008496 | HS3ST6 | 64711 | RNAseq | -6.1346 | 0.0000 | |
| SRP064894 | HS3ST6 | 64711 | RNAseq | -3.6996 | 0.0000 | |
| SRP133303 | HS3ST6 | 64711 | RNAseq | -3.3832 | 0.0000 | |
| SRP159526 | HS3ST6 | 64711 | RNAseq | -2.4523 | 0.0001 | |
| TCGA | HS3ST6 | 64711 | RNAseq | 0.6988 | 0.2138 |
Upregulated datasets: 0; Downregulated datasets: 9.
Survival by HS3ST6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HS3ST6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HS3ST6 | 64711 | 5 | 5 | 20 | |
| GSE20123 | HS3ST6 | 64711 | 5 | 4 | 21 | |
| GSE43470 | HS3ST6 | 64711 | 4 | 7 | 32 | |
| GSE46452 | HS3ST6 | 64711 | 38 | 1 | 20 | |
| GSE47630 | HS3ST6 | 64711 | 13 | 6 | 21 | |
| GSE54993 | HS3ST6 | 64711 | 3 | 5 | 62 | |
| GSE54994 | HS3ST6 | 64711 | 5 | 9 | 39 | |
| GSE60625 | HS3ST6 | 64711 | 4 | 0 | 7 | |
| GSE74703 | HS3ST6 | 64711 | 4 | 5 | 27 | |
| GSE74704 | HS3ST6 | 64711 | 3 | 2 | 15 | |
| TCGA | HS3ST6 | 64711 | 19 | 14 | 63 |
Total number of gains: 103; Total number of losses: 58; Total Number of normals: 327.
Somatic mutations of HS3ST6:
Generating mutation plots.
Highly correlated genes for HS3ST6:
Showing top 20/1181 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HS3ST6 | UPK3B | 0.859919 | 3 | 0 | 3 |
| HS3ST6 | NCCRP1 | 0.843673 | 3 | 0 | 3 |
| HS3ST6 | SNORA68 | 0.815235 | 3 | 0 | 3 |
| HS3ST6 | VSIG10L | 0.811197 | 6 | 0 | 6 |
| HS3ST6 | EVPL | 0.804843 | 6 | 0 | 6 |
| HS3ST6 | ACPP | 0.800932 | 6 | 0 | 6 |
| HS3ST6 | A2ML1 | 0.791923 | 6 | 0 | 6 |
| HS3ST6 | ENDOU | 0.791805 | 6 | 0 | 6 |
| HS3ST6 | IQCF1 | 0.790976 | 4 | 0 | 4 |
| HS3ST6 | MAPK3 | 0.787084 | 6 | 0 | 6 |
| HS3ST6 | BNIPL | 0.787081 | 6 | 0 | 6 |
| HS3ST6 | SMDT1 | 0.785956 | 3 | 0 | 3 |
| HS3ST6 | RHCG | 0.783943 | 6 | 0 | 6 |
| HS3ST6 | FAM3D | 0.780847 | 6 | 0 | 6 |
| HS3ST6 | ZNF185 | 0.778911 | 6 | 0 | 6 |
| HS3ST6 | CLCA4 | 0.778781 | 6 | 0 | 6 |
| HS3ST6 | KRT78 | 0.776745 | 6 | 0 | 6 |
| HS3ST6 | PPL | 0.776306 | 6 | 0 | 6 |
| HS3ST6 | APOBEC1 | 0.775931 | 4 | 0 | 4 |
| HS3ST6 | SLURP1 | 0.774051 | 6 | 0 | 6 |
For details and further investigation, click here
