ENDOU

 

Full name: endonuclease, poly(U) specific Alias Symbol: PP11|P11|PRSS26
Type: protein-coding gene Cytoband: 12q13.11
Entrez ID: 8909 HGNC ID: HGNC:14369 Ensembl Gene: ENSG00000111405 OMIM ID: 606720
Drug and gene relationship at DGIdb

 

Expression of ENDOU:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ENDOU 8909 206605_at -4.2641 0.0350
GSE20347 ENDOU 8909 206605_at -4.5629 0.0000
GSE23400 ENDOU 8909 206605_at -3.3986 0.0000
GSE26886 ENDOU 8909 206605_at -5.6647 0.0000
GSE29001 ENDOU 8909 206605_at -4.4860 0.0000
GSE38129 ENDOU 8909 206605_at -3.7203 0.0000
GSE45670 ENDOU 8909 206605_at -2.1988 0.0046
GSE53622 ENDOU 8909 10006 -4.3465 0.0000
GSE53624 ENDOU 8909 10006 -5.4909 0.0000
GSE63941 ENDOU 8909 206605_at 0.2910 0.1643
GSE77861 ENDOU 8909 206605_at -3.3156 0.0008
GSE97050 ENDOU 8909 A_24_P52887 -2.1377 0.1221
SRP007169 ENDOU 8909 RNAseq -7.0721 0.0000
SRP008496 ENDOU 8909 RNAseq -4.9714 0.0000
SRP064894 ENDOU 8909 RNAseq -4.6742 0.0000
SRP133303 ENDOU 8909 RNAseq -4.9966 0.0000
SRP159526 ENDOU 8909 RNAseq -6.5777 0.0000
SRP219564 ENDOU 8909 RNAseq -5.1344 0.0000
TCGA ENDOU 8909 RNAseq -0.2538 0.6388

Upregulated datasets: 0; Downregulated datasets: 16.  

 

Survival by ENDOU expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of ENDOU:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ENDOU 8909 7 1 22
GSE20123 ENDOU 8909 7 1 22
GSE43470 ENDOU 8909 3 1 39
GSE46452 ENDOU 8909 8 1 50
GSE47630 ENDOU 8909 11 2 27
GSE54993 ENDOU 8909 0 5 65
GSE54994 ENDOU 8909 6 1 46
GSE60625 ENDOU 8909 0 0 11
GSE74703 ENDOU 8909 3 1 32
GSE74704 ENDOU 8909 4 1 15
TCGA ENDOU 8909 16 12 68

Total number of gains: 65; Total number of losses: 26; Total Number of normals: 397.  

 

Somatic mutations of ENDOU:

 

Generating mutation plots.

 

Highly correlated genes for ENDOU:

 

Showing top 20/1716 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ENDOUCYSRT10.936164606
ENDOUKRT780.918121707
ENDOUCLIC30.916924909
ENDOUCRISP30.914511011
ENDOUGYS20.90601710010
ENDOUSASH10.89937311011
ENDOUEPGN0.898887303
ENDOUGBP60.88957404
ENDOUTMPRSS11B0.889486707
ENDOUCAPN140.888878606
ENDOUHCG220.884286606
ENDOUSFTA20.883114404
ENDOUCWH430.88145710010
ENDOUHOPX0.87889511011
ENDOUCXCR20.87866511011
ENDOUSERPINB10.87779811011
ENDOUGDPD30.87777212011
ENDOURANBP90.87676311011
ENDOUCRCT10.87507911011
ENDOUBNIPL0.874569707

For details and further investigation, click here