| Full name: DEAH-box helicase 38 | Alias Symbol: PRP16|KIAA0224|hPrp16|PRPF16 | ||
| Type: protein-coding gene | Cytoband: 16q22.2 | ||
| Entrez ID: 9785 | HGNC ID: HGNC:17211 | Ensembl Gene: ENSG00000140829 | OMIM ID: 605584 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of DHX38:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DHX38 | 9785 | 209178_at | 0.2488 | 0.4562 | |
| GSE20347 | DHX38 | 9785 | 209178_at | 0.0512 | 0.5770 | |
| GSE23400 | DHX38 | 9785 | 209178_at | 0.0567 | 0.1541 | |
| GSE26886 | DHX38 | 9785 | 209178_at | 0.0828 | 0.5525 | |
| GSE29001 | DHX38 | 9785 | 209178_at | 0.2464 | 0.0749 | |
| GSE38129 | DHX38 | 9785 | 209178_at | 0.0571 | 0.4708 | |
| GSE45670 | DHX38 | 9785 | 209178_at | 0.1759 | 0.0538 | |
| GSE53622 | DHX38 | 9785 | 106387 | 0.2358 | 0.0008 | |
| GSE53624 | DHX38 | 9785 | 106387 | 0.3053 | 0.0000 | |
| GSE63941 | DHX38 | 9785 | 209178_at | 0.7297 | 0.0081 | |
| GSE77861 | DHX38 | 9785 | 209178_at | 0.1281 | 0.4747 | |
| GSE97050 | DHX38 | 9785 | A_23_P38011 | 0.1595 | 0.6222 | |
| SRP007169 | DHX38 | 9785 | RNAseq | 1.2438 | 0.0277 | |
| SRP008496 | DHX38 | 9785 | RNAseq | 1.1178 | 0.0009 | |
| SRP064894 | DHX38 | 9785 | RNAseq | 0.1525 | 0.2561 | |
| SRP133303 | DHX38 | 9785 | RNAseq | 0.2206 | 0.1307 | |
| SRP159526 | DHX38 | 9785 | RNAseq | 0.1030 | 0.6815 | |
| SRP193095 | DHX38 | 9785 | RNAseq | 0.3427 | 0.0015 | |
| SRP219564 | DHX38 | 9785 | RNAseq | -0.0259 | 0.8681 | |
| TCGA | DHX38 | 9785 | RNAseq | 0.0104 | 0.8228 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by DHX38 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DHX38:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DHX38 | 9785 | 4 | 0 | 26 | |
| GSE20123 | DHX38 | 9785 | 4 | 0 | 26 | |
| GSE43470 | DHX38 | 9785 | 2 | 8 | 33 | |
| GSE46452 | DHX38 | 9785 | 38 | 2 | 19 | |
| GSE47630 | DHX38 | 9785 | 11 | 8 | 21 | |
| GSE54993 | DHX38 | 9785 | 2 | 4 | 64 | |
| GSE54994 | DHX38 | 9785 | 8 | 10 | 35 | |
| GSE60625 | DHX38 | 9785 | 4 | 0 | 7 | |
| GSE74703 | DHX38 | 9785 | 2 | 5 | 29 | |
| GSE74704 | DHX38 | 9785 | 2 | 0 | 18 | |
| TCGA | DHX38 | 9785 | 25 | 15 | 56 |
Total number of gains: 102; Total number of losses: 52; Total Number of normals: 334.
Somatic mutations of DHX38:
Generating mutation plots.
Highly correlated genes for DHX38:
Showing top 20/395 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DHX38 | HSDL1 | 0.8351 | 3 | 0 | 3 |
| DHX38 | MEX3B | 0.808042 | 3 | 0 | 3 |
| DHX38 | ZCCHC17 | 0.799126 | 3 | 0 | 3 |
| DHX38 | TMEM205 | 0.795494 | 3 | 0 | 3 |
| DHX38 | SAMM50 | 0.765441 | 3 | 0 | 3 |
| DHX38 | POLE3 | 0.755074 | 3 | 0 | 3 |
| DHX38 | NSMCE2 | 0.738471 | 4 | 0 | 4 |
| DHX38 | DARS2 | 0.726358 | 3 | 0 | 3 |
| DHX38 | SLC7A6OS | 0.725857 | 4 | 0 | 3 |
| DHX38 | ACO2 | 0.723494 | 3 | 0 | 3 |
| DHX38 | HARS2 | 0.716091 | 4 | 0 | 4 |
| DHX38 | RNF31 | 0.713671 | 3 | 0 | 3 |
| DHX38 | E2F4 | 0.702209 | 4 | 0 | 4 |
| DHX38 | MRPL30 | 0.70113 | 4 | 0 | 3 |
| DHX38 | COX4I1 | 0.700925 | 4 | 0 | 4 |
| DHX38 | PSAP | 0.700701 | 3 | 0 | 3 |
| DHX38 | OCEL1 | 0.697966 | 3 | 0 | 3 |
| DHX38 | TRUB2 | 0.69559 | 3 | 0 | 3 |
| DHX38 | TRIM28 | 0.695509 | 5 | 0 | 5 |
| DHX38 | ABCF2 | 0.689678 | 3 | 0 | 3 |
For details and further investigation, click here
