| Full name: translational activator of cytochrome c oxidase I | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 17q23.3 | ||
| Entrez ID: 51204 | HGNC ID: HGNC:24316 | Ensembl Gene: ENSG00000136463 | OMIM ID: 612958 |
| Drug and gene relationship at DGIdb | |||
Expression of TACO1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TACO1 | 51204 | 221069_s_at | 0.2829 | 0.2462 | |
| GSE20347 | TACO1 | 51204 | 221069_s_at | 0.3419 | 0.0135 | |
| GSE23400 | TACO1 | 51204 | 221069_s_at | 0.1885 | 0.0001 | |
| GSE26886 | TACO1 | 51204 | 221069_s_at | 0.1189 | 0.5219 | |
| GSE29001 | TACO1 | 51204 | 221069_s_at | 0.5177 | 0.0684 | |
| GSE38129 | TACO1 | 51204 | 221069_s_at | 0.3980 | 0.0003 | |
| GSE45670 | TACO1 | 51204 | 221069_s_at | 0.3990 | 0.0057 | |
| GSE53622 | TACO1 | 51204 | 65931 | 0.3472 | 0.0000 | |
| GSE53624 | TACO1 | 51204 | 65931 | 0.4621 | 0.0000 | |
| GSE63941 | TACO1 | 51204 | 221069_s_at | 0.1773 | 0.6330 | |
| GSE77861 | TACO1 | 51204 | 221069_s_at | 0.5108 | 0.0053 | |
| GSE97050 | TACO1 | 51204 | A_23_P73142 | 0.2758 | 0.3182 | |
| SRP007169 | TACO1 | 51204 | RNAseq | 0.2957 | 0.5277 | |
| SRP008496 | TACO1 | 51204 | RNAseq | 0.3267 | 0.3643 | |
| SRP064894 | TACO1 | 51204 | RNAseq | 0.7687 | 0.0018 | |
| SRP133303 | TACO1 | 51204 | RNAseq | 0.7101 | 0.0002 | |
| SRP159526 | TACO1 | 51204 | RNAseq | 0.6461 | 0.0041 | |
| SRP193095 | TACO1 | 51204 | RNAseq | 0.2513 | 0.0308 | |
| SRP219564 | TACO1 | 51204 | RNAseq | 0.5929 | 0.2014 | |
| TCGA | TACO1 | 51204 | RNAseq | 0.0427 | 0.4821 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TACO1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TACO1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TACO1 | 51204 | 3 | 1 | 26 | |
| GSE20123 | TACO1 | 51204 | 3 | 1 | 26 | |
| GSE43470 | TACO1 | 51204 | 4 | 0 | 39 | |
| GSE46452 | TACO1 | 51204 | 31 | 0 | 28 | |
| GSE47630 | TACO1 | 51204 | 7 | 1 | 32 | |
| GSE54993 | TACO1 | 51204 | 2 | 5 | 63 | |
| GSE54994 | TACO1 | 51204 | 9 | 4 | 40 | |
| GSE60625 | TACO1 | 51204 | 4 | 0 | 7 | |
| GSE74703 | TACO1 | 51204 | 4 | 0 | 32 | |
| GSE74704 | TACO1 | 51204 | 3 | 1 | 16 | |
| TCGA | TACO1 | 51204 | 31 | 8 | 57 |
Total number of gains: 101; Total number of losses: 21; Total Number of normals: 366.
Somatic mutations of TACO1:
Generating mutation plots.
Highly correlated genes for TACO1:
Showing top 20/1444 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TACO1 | ALKBH6 | 0.79702 | 3 | 0 | 3 |
| TACO1 | HELZ | 0.76005 | 3 | 0 | 3 |
| TACO1 | ASF1A | 0.747683 | 3 | 0 | 3 |
| TACO1 | RIOK2 | 0.743315 | 3 | 0 | 3 |
| TACO1 | IRF2BPL | 0.739985 | 4 | 0 | 4 |
| TACO1 | CDC40 | 0.735869 | 3 | 0 | 3 |
| TACO1 | CYP26B1 | 0.734296 | 3 | 0 | 3 |
| TACO1 | TRAF7 | 0.732522 | 4 | 0 | 4 |
| TACO1 | MRPS23 | 0.729983 | 8 | 0 | 6 |
| TACO1 | TMEM167A | 0.7269 | 3 | 0 | 3 |
| TACO1 | C15orf61 | 0.725376 | 3 | 0 | 3 |
| TACO1 | HSDL1 | 0.720731 | 3 | 0 | 3 |
| TACO1 | AGTRAP | 0.719815 | 3 | 0 | 3 |
| TACO1 | SPRED1 | 0.717353 | 4 | 0 | 3 |
| TACO1 | NACC1 | 0.716256 | 3 | 0 | 3 |
| TACO1 | INSIG2 | 0.714397 | 4 | 0 | 3 |
| TACO1 | HSD17B11 | 0.707174 | 3 | 0 | 3 |
| TACO1 | FABP4 | 0.707129 | 3 | 0 | 3 |
| TACO1 | CHCHD2 | 0.706025 | 7 | 0 | 7 |
| TACO1 | AAK1 | 0.705979 | 4 | 0 | 3 |
For details and further investigation, click here
