| Full name: proteasome 26S subunit, non-ATPase 1 | Alias Symbol: S1|P112|Rpn2 | ||
| Type: protein-coding gene | Cytoband: 2q37.1 | ||
| Entrez ID: 5707 | HGNC ID: HGNC:9554 | Ensembl Gene: ENSG00000173692 | OMIM ID: 617842 |
| Drug and gene relationship at DGIdb | |||
Expression of PSMD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PSMD1 | 5707 | 201199_s_at | 0.0220 | 0.9678 | |
| GSE20347 | PSMD1 | 5707 | 201199_s_at | -0.0179 | 0.8676 | |
| GSE23400 | PSMD1 | 5707 | 201199_s_at | 0.1706 | 0.0003 | |
| GSE26886 | PSMD1 | 5707 | 201199_s_at | 0.4815 | 0.0122 | |
| GSE29001 | PSMD1 | 5707 | 201199_s_at | 0.0777 | 0.8018 | |
| GSE38129 | PSMD1 | 5707 | 201199_s_at | 0.1376 | 0.1398 | |
| GSE45670 | PSMD1 | 5707 | 201199_s_at | 0.3126 | 0.0051 | |
| GSE53622 | PSMD1 | 5707 | 61294 | 0.2278 | 0.0004 | |
| GSE53624 | PSMD1 | 5707 | 86102 | 0.2452 | 0.0000 | |
| GSE63941 | PSMD1 | 5707 | 201199_s_at | -0.2790 | 0.3348 | |
| GSE77861 | PSMD1 | 5707 | 201199_s_at | 0.5147 | 0.0072 | |
| GSE97050 | PSMD1 | 5707 | A_23_P209740 | 0.0901 | 0.6467 | |
| SRP007169 | PSMD1 | 5707 | RNAseq | -0.1584 | 0.6632 | |
| SRP008496 | PSMD1 | 5707 | RNAseq | -0.1198 | 0.5066 | |
| SRP064894 | PSMD1 | 5707 | RNAseq | 0.1182 | 0.4616 | |
| SRP133303 | PSMD1 | 5707 | RNAseq | 0.3903 | 0.0010 | |
| SRP159526 | PSMD1 | 5707 | RNAseq | 0.2457 | 0.0491 | |
| SRP193095 | PSMD1 | 5707 | RNAseq | -0.0327 | 0.7785 | |
| SRP219564 | PSMD1 | 5707 | RNAseq | -0.2089 | 0.5319 | |
| TCGA | PSMD1 | 5707 | RNAseq | 0.0956 | 0.0236 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PSMD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PSMD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PSMD1 | 5707 | 1 | 13 | 16 | |
| GSE20123 | PSMD1 | 5707 | 1 | 12 | 17 | |
| GSE43470 | PSMD1 | 5707 | 1 | 8 | 34 | |
| GSE46452 | PSMD1 | 5707 | 0 | 5 | 54 | |
| GSE47630 | PSMD1 | 5707 | 4 | 5 | 31 | |
| GSE54993 | PSMD1 | 5707 | 2 | 2 | 66 | |
| GSE54994 | PSMD1 | 5707 | 6 | 11 | 36 | |
| GSE60625 | PSMD1 | 5707 | 0 | 3 | 8 | |
| GSE74703 | PSMD1 | 5707 | 1 | 6 | 29 | |
| GSE74704 | PSMD1 | 5707 | 1 | 5 | 14 | |
| TCGA | PSMD1 | 5707 | 13 | 27 | 56 |
Total number of gains: 30; Total number of losses: 97; Total Number of normals: 361.
Somatic mutations of PSMD1:
Generating mutation plots.
Highly correlated genes for PSMD1:
Showing top 20/906 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PSMD1 | VPS26A | 0.847189 | 3 | 0 | 3 |
| PSMD1 | ATF1 | 0.820685 | 3 | 0 | 3 |
| PSMD1 | AKAP8 | 0.807427 | 3 | 0 | 3 |
| PSMD1 | PCBP2 | 0.782075 | 3 | 0 | 3 |
| PSMD1 | ACAP2 | 0.772502 | 3 | 0 | 3 |
| PSMD1 | MRPL37 | 0.771054 | 3 | 0 | 3 |
| PSMD1 | TMEM117 | 0.754438 | 3 | 0 | 3 |
| PSMD1 | EIF1B | 0.749602 | 3 | 0 | 3 |
| PSMD1 | HSD17B11 | 0.747762 | 3 | 0 | 3 |
| PSMD1 | ZNF207 | 0.747645 | 3 | 0 | 3 |
| PSMD1 | HAS3 | 0.745044 | 3 | 0 | 3 |
| PSMD1 | NANOS1 | 0.744419 | 3 | 0 | 3 |
| PSMD1 | SPNS1 | 0.744067 | 3 | 0 | 3 |
| PSMD1 | NDUFS1 | 0.740234 | 3 | 0 | 3 |
| PSMD1 | CDC42SE2 | 0.738544 | 3 | 0 | 3 |
| PSMD1 | HSDL1 | 0.737466 | 3 | 0 | 3 |
| PSMD1 | METAP2 | 0.73586 | 4 | 0 | 4 |
| PSMD1 | CYP20A1 | 0.732012 | 3 | 0 | 3 |
| PSMD1 | SARNP | 0.731207 | 3 | 0 | 3 |
| PSMD1 | IMPACT | 0.730078 | 4 | 0 | 4 |
For details and further investigation, click here
