| Full name: histatin 3 | Alias Symbol: HIS2 | ||
| Type: protein-coding gene | Cytoband: 4q13.3 | ||
| Entrez ID: 3347 | HGNC ID: HGNC:5284 | Ensembl Gene: ENSG00000205649 | OMIM ID: 142702 |
| Drug and gene relationship at DGIdb | |||
Expression of HTN3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HTN3 | 3347 | 206786_at | 0.1555 | 0.5672 | |
| GSE20347 | HTN3 | 3347 | 206786_at | 0.0298 | 0.6452 | |
| GSE23400 | HTN3 | 3347 | 206786_at | -0.0147 | 0.6734 | |
| GSE26886 | HTN3 | 3347 | 206786_at | 0.1196 | 0.1157 | |
| GSE29001 | HTN3 | 3347 | 206786_at | -0.0753 | 0.6378 | |
| GSE38129 | HTN3 | 3347 | 206786_at | 0.0165 | 0.7970 | |
| GSE45670 | HTN3 | 3347 | 206786_at | 0.0769 | 0.2357 | |
| GSE53622 | HTN3 | 3347 | 76908 | -0.6712 | 0.0000 | |
| GSE53624 | HTN3 | 3347 | 76908 | -0.1833 | 0.3090 | |
| GSE63941 | HTN3 | 3347 | 206786_at | 0.0247 | 0.8635 | |
| GSE77861 | HTN3 | 3347 | 206786_at | -0.0357 | 0.6659 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HTN3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HTN3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HTN3 | 3347 | 0 | 10 | 20 | |
| GSE20123 | HTN3 | 3347 | 0 | 11 | 19 | |
| GSE43470 | HTN3 | 3347 | 0 | 13 | 30 | |
| GSE46452 | HTN3 | 3347 | 2 | 35 | 22 | |
| GSE47630 | HTN3 | 3347 | 1 | 18 | 21 | |
| GSE54993 | HTN3 | 3347 | 7 | 0 | 63 | |
| GSE54994 | HTN3 | 3347 | 1 | 9 | 43 | |
| GSE60625 | HTN3 | 3347 | 0 | 0 | 11 | |
| GSE74703 | HTN3 | 3347 | 0 | 11 | 25 | |
| GSE74704 | HTN3 | 3347 | 0 | 7 | 13 | |
| TCGA | HTN3 | 3347 | 15 | 28 | 53 |
Total number of gains: 26; Total number of losses: 142; Total Number of normals: 320.
Somatic mutations of HTN3:
Generating mutation plots.
Highly correlated genes for HTN3:
Showing top 20/132 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HTN3 | SPATA12 | 0.716704 | 3 | 0 | 3 |
| HTN3 | MAGEA8 | 0.706419 | 3 | 0 | 3 |
| HTN3 | OBSL1 | 0.677652 | 3 | 0 | 3 |
| HTN3 | NANOG | 0.655958 | 3 | 0 | 3 |
| HTN3 | HKDC1 | 0.654944 | 3 | 0 | 3 |
| HTN3 | NTSR2 | 0.642964 | 3 | 0 | 3 |
| HTN3 | RIT2 | 0.642642 | 3 | 0 | 3 |
| HTN3 | TP53I11 | 0.634433 | 3 | 0 | 3 |
| HTN3 | OR10H3 | 0.630044 | 4 | 0 | 4 |
| HTN3 | SYT13 | 0.623309 | 4 | 0 | 3 |
| HTN3 | SGK2 | 0.621985 | 4 | 0 | 4 |
| HTN3 | BCAS4 | 0.620057 | 4 | 0 | 4 |
| HTN3 | ANGPT2 | 0.614665 | 3 | 0 | 3 |
| HTN3 | RFPL2 | 0.612703 | 5 | 0 | 4 |
| HTN3 | CCDC33 | 0.609383 | 4 | 0 | 3 |
| HTN3 | MYOD1 | 0.607101 | 3 | 0 | 3 |
| HTN3 | PLA2G2F | 0.605006 | 4 | 0 | 3 |
| HTN3 | ARR3 | 0.600705 | 4 | 0 | 4 |
| HTN3 | CASR | 0.597069 | 4 | 0 | 3 |
| HTN3 | RORB | 0.596629 | 3 | 0 | 3 |
For details and further investigation, click here
