BCAS4

 

Full name: breast carcinoma amplified sequence 4 Alias Symbol: FLJ20495|CNOL
Type: protein-coding gene Cytoband: 20q13.13
Entrez ID: 55653 HGNC ID: HGNC:14367 Ensembl Gene: ENSG00000124243 OMIM ID: 607471
Drug and gene relationship at DGIdb

 

Expression of BCAS4:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 BCAS4 55653 228787_s_at 0.2698 0.2882
GSE20347 BCAS4 55653 220588_at 0.3749 0.0140
GSE23400 BCAS4 55653 220588_at 0.0777 0.1642
GSE26886 BCAS4 55653 228787_s_at 0.6201 0.0000
GSE29001 BCAS4 55653 220588_at -0.0100 0.9580
GSE38129 BCAS4 55653 220588_at 0.5457 0.0068
GSE45670 BCAS4 55653 228787_s_at 0.4241 0.0020
GSE53622 BCAS4 55653 63789 0.5236 0.0017
GSE53624 BCAS4 55653 63789 0.9065 0.0000
GSE63941 BCAS4 55653 228787_s_at 0.2161 0.6473
GSE77861 BCAS4 55653 228787_s_at 0.0083 0.9688
GSE97050 BCAS4 A_21_P0007218 0.1126 0.7325
SRP007169 BCAS4 55653 RNAseq 0.6320 0.4281
SRP008496 BCAS4 55653 RNAseq 1.6380 0.0008
SRP064894 BCAS4 55653 RNAseq 0.9025 0.0351
SRP133303 BCAS4 55653 RNAseq 0.8228 0.0004
SRP159526 BCAS4 55653 RNAseq 1.2320 0.0252
SRP193095 BCAS4 55653 RNAseq 1.2861 0.0000
SRP219564 BCAS4 55653 RNAseq 1.5978 0.0006
TCGA BCAS4 55653 RNAseq -0.0254 0.8045

Upregulated datasets: 4; Downregulated datasets: 0.  


 

Survival by BCAS4 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of BCAS4:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 BCAS4 55653 16 2 12
GSE20123 BCAS4 55653 16 2 12
GSE43470 BCAS4 55653 13 0 30
GSE46452 BCAS4 55653 29 0 30
GSE47630 BCAS4 55653 24 1 15
GSE54993 BCAS4 55653 0 17 53
GSE54994 BCAS4 55653 27 0 26
GSE60625 BCAS4 55653 0 0 11
GSE74703 BCAS4 55653 11 0 25
GSE74704 BCAS4 55653 12 0 8
TCGA BCAS4 55653 46 3 47

Total number of gains: 194; Total number of losses: 25; Total Number of normals: 269.  


 

Somatic mutations of BCAS4:

 

Generating mutation plots.

 

Highly correlated genes for BCAS4:

 

Showing top 20/859 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
BCAS4PLEKHA40.805702404
BCAS4TRIM470.782305303
BCAS4MIF0.771256303
BCAS4NFAM10.767339404
BCAS4PTOV10.754345303
BCAS4DERL30.753577404
BCAS4PDGFRB0.753214403
BCAS4CYCS0.751894303
BCAS4CD3EAP0.747624303
BCAS4IDS0.734516303
BCAS4ZNF4140.734101303
BCAS4MEIS30.728924404
BCAS4RGS10.728631303
BCAS4INO80E0.7268303
BCAS4LRRC360.72585303
BCAS4EPPK10.722633303
BCAS4RNF1870.722221303
BCAS4A4GALT0.721976404
BCAS4HNRNPUL10.718322303
BCAS4TSEN340.711363303

For details and further investigation, click here