| Full name: phospholipase A2 group IIF | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1p36.12 | ||
| Entrez ID: 64600 | HGNC ID: HGNC:30040 | Ensembl Gene: ENSG00000158786 | OMIM ID: 616793 |
| Drug and gene relationship at DGIdb | |||
PLA2G2F involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04014 | Ras signaling pathway | |
| hsa04270 | Vascular smooth muscle contraction |
Expression of PLA2G2F:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PLA2G2F | 64600 | 221416_at | 0.0857 | 0.7812 | |
| GSE20347 | PLA2G2F | 64600 | 221416_at | 0.0458 | 0.6209 | |
| GSE23400 | PLA2G2F | 64600 | 221416_at | -0.0965 | 0.0014 | |
| GSE26886 | PLA2G2F | 64600 | 221416_at | -0.0507 | 0.6022 | |
| GSE29001 | PLA2G2F | 64600 | 221416_at | -0.0410 | 0.7058 | |
| GSE38129 | PLA2G2F | 64600 | 221416_at | -0.1021 | 0.1980 | |
| GSE45670 | PLA2G2F | 64600 | 221416_at | 0.0405 | 0.6602 | |
| GSE53622 | PLA2G2F | 64600 | 23695 | 0.4945 | 0.0000 | |
| GSE53624 | PLA2G2F | 64600 | 23695 | 0.0068 | 0.9519 | |
| GSE63941 | PLA2G2F | 64600 | 221416_at | 0.1608 | 0.3087 | |
| GSE77861 | PLA2G2F | 64600 | 221416_at | -0.0756 | 0.6181 | |
| GSE97050 | PLA2G2F | 64600 | A_24_P208081 | 0.2276 | 0.4469 | |
| TCGA | PLA2G2F | 64600 | RNAseq | 2.4859 | 0.0001 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by PLA2G2F expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PLA2G2F:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PLA2G2F | 64600 | 0 | 5 | 25 | |
| GSE20123 | PLA2G2F | 64600 | 0 | 4 | 26 | |
| GSE43470 | PLA2G2F | 64600 | 0 | 8 | 35 | |
| GSE46452 | PLA2G2F | 64600 | 5 | 1 | 53 | |
| GSE47630 | PLA2G2F | 64600 | 8 | 3 | 29 | |
| GSE54993 | PLA2G2F | 64600 | 3 | 1 | 66 | |
| GSE54994 | PLA2G2F | 64600 | 11 | 4 | 38 | |
| GSE60625 | PLA2G2F | 64600 | 0 | 0 | 11 | |
| GSE74703 | PLA2G2F | 64600 | 0 | 5 | 31 | |
| GSE74704 | PLA2G2F | 64600 | 0 | 0 | 20 | |
| TCGA | PLA2G2F | 64600 | 11 | 21 | 64 |
Total number of gains: 38; Total number of losses: 52; Total Number of normals: 398.
Somatic mutations of PLA2G2F:
Generating mutation plots.
Highly correlated genes for PLA2G2F:
Showing top 20/630 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PLA2G2F | RASL10B | 0.724463 | 3 | 0 | 3 |
| PLA2G2F | JSRP1 | 0.723466 | 3 | 0 | 3 |
| PLA2G2F | OR4D1 | 0.714899 | 3 | 0 | 3 |
| PLA2G2F | SLC6A18 | 0.712874 | 3 | 0 | 3 |
| PLA2G2F | TP73 | 0.710257 | 4 | 0 | 3 |
| PLA2G2F | TMEM221 | 0.70933 | 3 | 0 | 3 |
| PLA2G2F | CSH2 | 0.704541 | 3 | 0 | 3 |
| PLA2G2F | CACNA1A | 0.697408 | 3 | 0 | 3 |
| PLA2G2F | IL1F10 | 0.697009 | 5 | 0 | 5 |
| PLA2G2F | USHBP1 | 0.690587 | 3 | 0 | 3 |
| PLA2G2F | FOLH1 | 0.688817 | 5 | 0 | 5 |
| PLA2G2F | WFIKKN2 | 0.685771 | 3 | 0 | 3 |
| PLA2G2F | ODF3L2 | 0.676588 | 4 | 0 | 3 |
| PLA2G2F | STRC | 0.67596 | 3 | 0 | 3 |
| PLA2G2F | GGT1 | 0.668471 | 3 | 0 | 3 |
| PLA2G2F | CLDN14 | 0.667392 | 3 | 0 | 3 |
| PLA2G2F | GPSM3 | 0.667259 | 3 | 0 | 3 |
| PLA2G2F | CHST13 | 0.665162 | 3 | 0 | 3 |
| PLA2G2F | HDAC10 | 0.664555 | 4 | 0 | 3 |
| PLA2G2F | CDH4 | 0.662924 | 5 | 0 | 5 |
For details and further investigation, click here
