| Full name: apolipoprotein A4 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11q23.3 | ||
| Entrez ID: 337 | HGNC ID: HGNC:602 | Ensembl Gene: ENSG00000110244 | OMIM ID: 107690 |
| Drug and gene relationship at DGIdb | |||
Expression of APOA4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | APOA4 | 337 | 206894_at | 0.0485 | 0.8577 | |
| GSE20347 | APOA4 | 337 | 206894_at | -0.1744 | 0.0318 | |
| GSE23400 | APOA4 | 337 | 206894_at | -0.1448 | 0.0001 | |
| GSE26886 | APOA4 | 337 | 206894_at | 0.1587 | 0.3625 | |
| GSE29001 | APOA4 | 337 | 206894_at | -0.2591 | 0.0132 | |
| GSE38129 | APOA4 | 337 | 206894_at | -0.2016 | 0.0112 | |
| GSE45670 | APOA4 | 337 | 206894_at | -0.0582 | 0.5423 | |
| GSE53622 | APOA4 | 337 | 24489 | -0.1673 | 0.0196 | |
| GSE53624 | APOA4 | 337 | 24489 | -0.1094 | 0.1770 | |
| GSE63941 | APOA4 | 337 | 206894_at | 0.0261 | 0.8851 | |
| GSE77861 | APOA4 | 337 | 206894_at | -0.2204 | 0.0656 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by APOA4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of APOA4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | APOA4 | 337 | 0 | 13 | 17 | |
| GSE20123 | APOA4 | 337 | 0 | 13 | 17 | |
| GSE43470 | APOA4 | 337 | 2 | 8 | 33 | |
| GSE46452 | APOA4 | 337 | 3 | 26 | 30 | |
| GSE47630 | APOA4 | 337 | 2 | 19 | 19 | |
| GSE54993 | APOA4 | 337 | 10 | 0 | 60 | |
| GSE54994 | APOA4 | 337 | 5 | 19 | 29 | |
| GSE60625 | APOA4 | 337 | 0 | 3 | 8 | |
| GSE74703 | APOA4 | 337 | 1 | 5 | 30 | |
| GSE74704 | APOA4 | 337 | 0 | 9 | 11 | |
| TCGA | APOA4 | 337 | 5 | 50 | 41 |
Total number of gains: 28; Total number of losses: 165; Total Number of normals: 295.
Somatic mutations of APOA4:
Generating mutation plots.
Highly correlated genes for APOA4:
Showing top 20/967 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| APOA4 | GJC2 | 0.68644 | 7 | 0 | 6 |
| APOA4 | PIK3R5 | 0.679664 | 5 | 0 | 5 |
| APOA4 | HUS1B | 0.676946 | 3 | 0 | 3 |
| APOA4 | ITGB7 | 0.669094 | 5 | 0 | 5 |
| APOA4 | CRISP1 | 0.665754 | 3 | 0 | 3 |
| APOA4 | L3MBTL1 | 0.664109 | 7 | 0 | 6 |
| APOA4 | PRDM12 | 0.6618 | 5 | 0 | 3 |
| APOA4 | TMIE | 0.661249 | 4 | 0 | 4 |
| APOA4 | C3orf36 | 0.656674 | 5 | 0 | 5 |
| APOA4 | RIC3 | 0.655473 | 3 | 0 | 3 |
| APOA4 | CST9 | 0.655384 | 3 | 0 | 3 |
| APOA4 | HPCA | 0.655104 | 6 | 0 | 6 |
| APOA4 | KRT32 | 0.654841 | 5 | 0 | 5 |
| APOA4 | PIWIL2 | 0.654218 | 6 | 0 | 5 |
| APOA4 | AMACR | 0.653068 | 4 | 0 | 3 |
| APOA4 | NPEPL1 | 0.652892 | 7 | 0 | 6 |
| APOA4 | KCNH6 | 0.652457 | 3 | 0 | 3 |
| APOA4 | CDKL5 | 0.651757 | 4 | 0 | 3 |
| APOA4 | NRG2 | 0.651693 | 3 | 0 | 3 |
| APOA4 | FAM153A | 0.651448 | 8 | 0 | 7 |
For details and further investigation, click here
