LRRC19

 

Full name: leucine rich repeat containing 19 Alias Symbol: FLJ21302
Type: protein-coding gene Cytoband: 9p21.2
Entrez ID: 64922 HGNC ID: HGNC:23379 Ensembl Gene: ENSG00000184434 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of LRRC19:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 LRRC19 64922 220376_at -0.0290 0.9130
GSE20347 LRRC19 64922 220376_at -0.0726 0.1163
GSE23400 LRRC19 64922 220376_at -0.0437 0.0263
GSE26886 LRRC19 64922 220376_at 0.0850 0.2760
GSE29001 LRRC19 64922 220376_at -0.0703 0.4375
GSE38129 LRRC19 64922 220376_at -0.0981 0.0091
GSE45670 LRRC19 64922 220376_at -0.0189 0.8192
GSE63941 LRRC19 64922 220376_at 0.2564 0.2002
GSE77861 LRRC19 64922 220376_at -0.0369 0.6730
GSE97050 LRRC19 64922 A_23_P364625 0.1731 0.4212
SRP133303 LRRC19 64922 RNAseq 0.1390 0.5650
SRP159526 LRRC19 64922 RNAseq 0.9027 0.0746
SRP193095 LRRC19 64922 RNAseq -0.1768 0.2826
TCGA LRRC19 64922 RNAseq 0.4218 0.1485

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by LRRC19 expression:

 

TCGA

 

Note: Click image to view full size file.  


Copy number change of LRRC19:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 LRRC19 64922 2 14 14
GSE20123 LRRC19 64922 2 14 14
GSE43470 LRRC19 64922 2 11 30
GSE46452 LRRC19 64922 6 18 35
GSE47630 LRRC19 64922 1 22 17
GSE54993 LRRC19 64922 7 0 63
GSE54994 LRRC19 64922 7 15 31
GSE60625 LRRC19 64922 0 0 11
GSE74703 LRRC19 64922 2 8 26
GSE74704 LRRC19 64922 0 11 9
TCGA LRRC19 64922 16 46 34

Total number of gains: 45; Total number of losses: 159; Total Number of normals: 284.  


 

Somatic mutations of LRRC19:

 

Generating mutation plots.

 

Highly correlated genes for LRRC19:

 

Showing top 20/137 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
LRRC19KRT350.712638303
LRRC19ADAM210.702156303
LRRC19C3orf200.676485303
LRRC19HUS1B0.666028303
LRRC19SH2D1B0.659342303
LRRC19CLEC4M0.646286403
LRRC19CDX20.62923403
LRRC19GPR320.628263403
LRRC19GPR1820.620316403
LRRC19AGRP0.61946504
LRRC19FOLH10.614857603
LRRC19REG3A0.61402503
LRRC19RASGRF10.608953303
LRRC19CTSE0.607325403
LRRC19C3orf360.605529604
LRRC19GALR20.605241403
LRRC19CABP70.602817403
LRRC19CRYGN0.602788403
LRRC19OR12D30.599236403
LRRC19ANKFN10.59757505

For details and further investigation, click here