| Full name: folate receptor beta | Alias Symbol: FRβ | ||
| Type: protein-coding gene | Cytoband: 11q13.4 | ||
| Entrez ID: 2350 | HGNC ID: HGNC:3793 | Ensembl Gene: ENSG00000165457 | OMIM ID: 136425 |
| Drug and gene relationship at DGIdb | |||
Expression of FOLR2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FOLR2 | 2350 | 204829_s_at | -0.5721 | 0.3490 | |
| GSE20347 | FOLR2 | 2350 | 204829_s_at | 0.0115 | 0.9095 | |
| GSE23400 | FOLR2 | 2350 | 204829_s_at | -0.1112 | 0.0559 | |
| GSE26886 | FOLR2 | 2350 | 204829_s_at | 0.3703 | 0.0615 | |
| GSE29001 | FOLR2 | 2350 | 204829_s_at | -0.0352 | 0.8313 | |
| GSE38129 | FOLR2 | 2350 | 204829_s_at | -0.3205 | 0.0204 | |
| GSE45670 | FOLR2 | 2350 | 204829_s_at | -0.9083 | 0.0001 | |
| GSE53622 | FOLR2 | 2350 | 48615 | -0.6690 | 0.0000 | |
| GSE53624 | FOLR2 | 2350 | 48615 | -1.0264 | 0.0000 | |
| GSE63941 | FOLR2 | 2350 | 204829_s_at | 0.5025 | 0.0044 | |
| GSE77861 | FOLR2 | 2350 | 229619_at | -0.0323 | 0.8035 | |
| GSE97050 | FOLR2 | 2350 | A_24_P32935 | 0.0873 | 0.8536 | |
| SRP007169 | FOLR2 | 2350 | RNAseq | 1.0322 | 0.1317 | |
| SRP064894 | FOLR2 | 2350 | RNAseq | -0.3083 | 0.5114 | |
| SRP133303 | FOLR2 | 2350 | RNAseq | -0.1784 | 0.7032 | |
| SRP159526 | FOLR2 | 2350 | RNAseq | 0.6361 | 0.2993 | |
| SRP193095 | FOLR2 | 2350 | RNAseq | 0.5457 | 0.3000 | |
| SRP219564 | FOLR2 | 2350 | RNAseq | 0.9892 | 0.3612 | |
| TCGA | FOLR2 | 2350 | RNAseq | -0.3635 | 0.1483 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by FOLR2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FOLR2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FOLR2 | 2350 | 10 | 7 | 13 | |
| GSE20123 | FOLR2 | 2350 | 10 | 7 | 13 | |
| GSE43470 | FOLR2 | 2350 | 9 | 4 | 30 | |
| GSE46452 | FOLR2 | 2350 | 12 | 17 | 30 | |
| GSE47630 | FOLR2 | 2350 | 10 | 10 | 20 | |
| GSE54993 | FOLR2 | 2350 | 7 | 3 | 60 | |
| GSE54994 | FOLR2 | 2350 | 12 | 12 | 29 | |
| GSE60625 | FOLR2 | 2350 | 0 | 7 | 4 | |
| GSE74703 | FOLR2 | 2350 | 7 | 3 | 26 | |
| GSE74704 | FOLR2 | 2350 | 7 | 4 | 9 | |
| TCGA | FOLR2 | 2350 | 35 | 20 | 41 |
Total number of gains: 119; Total number of losses: 94; Total Number of normals: 275.
Somatic mutations of FOLR2:
Generating mutation plots.
Highly correlated genes for FOLR2:
Showing top 20/248 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FOLR2 | RNASE1 | 0.698489 | 7 | 0 | 7 |
| FOLR2 | KCND1 | 0.688339 | 3 | 0 | 3 |
| FOLR2 | C16orf86 | 0.68824 | 3 | 0 | 3 |
| FOLR2 | PLCXD3 | 0.679015 | 4 | 0 | 3 |
| FOLR2 | ACRBP | 0.675599 | 3 | 0 | 3 |
| FOLR2 | LILRB5 | 0.667861 | 9 | 0 | 8 |
| FOLR2 | MPEG1 | 0.667767 | 4 | 0 | 4 |
| FOLR2 | LYVE1 | 0.664327 | 11 | 0 | 8 |
| FOLR2 | HUS1B | 0.660843 | 3 | 0 | 3 |
| FOLR2 | GGT5 | 0.66066 | 3 | 0 | 3 |
| FOLR2 | CLEC14A | 0.655635 | 5 | 0 | 5 |
| FOLR2 | ATF6 | 0.65262 | 4 | 0 | 4 |
| FOLR2 | MRC1 | 0.649669 | 7 | 0 | 6 |
| FOLR2 | MS4A4A | 0.644644 | 9 | 0 | 7 |
| FOLR2 | C3 | 0.641884 | 8 | 0 | 6 |
| FOLR2 | SCRG1 | 0.638519 | 6 | 0 | 6 |
| FOLR2 | NUDT16 | 0.635208 | 3 | 0 | 3 |
| FOLR2 | TPK1 | 0.631555 | 6 | 0 | 3 |
| FOLR2 | CMA1 | 0.630543 | 9 | 0 | 5 |
| FOLR2 | CHRDL1 | 0.630094 | 7 | 0 | 6 |
For details and further investigation, click here
