AUP1

 

Full name: AUP1 lipid droplet regulating VLDL assembly factor Alias Symbol: 
Type: protein-coding gene Cytoband: 2p13.1
Entrez ID: 550 HGNC ID: HGNC:891 Ensembl Gene: ENSG00000115307 OMIM ID: 602434
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of AUP1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 AUP1 550 220525_s_at 0.5088 0.2110
GSE20347 AUP1 550 220525_s_at 0.2736 0.0135
GSE23400 AUP1 550 220525_s_at 0.4680 0.0000
GSE26886 AUP1 550 220525_s_at 0.5719 0.0027
GSE29001 AUP1 550 220525_s_at 0.2808 0.2922
GSE38129 AUP1 550 220525_s_at 0.4827 0.0000
GSE45670 AUP1 550 220525_s_at 0.6043 0.0002
GSE53622 AUP1 550 93053 0.7459 0.0000
GSE53624 AUP1 550 70370 0.5514 0.0000
GSE63941 AUP1 550 220525_s_at 0.6441 0.0495
GSE77861 AUP1 550 220525_s_at 0.4510 0.0142
GSE97050 AUP1 550 A_23_P253421 0.8066 0.0700
SRP007169 AUP1 550 RNAseq -0.2189 0.5936
SRP008496 AUP1 550 RNAseq -0.2601 0.2125
SRP064894 AUP1 550 RNAseq 0.5932 0.0030
SRP133303 AUP1 550 RNAseq 0.6728 0.0001
SRP159526 AUP1 550 RNAseq 0.5503 0.0090
SRP193095 AUP1 550 RNAseq 0.3090 0.0017
SRP219564 AUP1 550 RNAseq 0.6665 0.1385
TCGA AUP1 550 RNAseq 0.0778 0.0873

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by AUP1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of AUP1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 AUP1 550 9 2 19
GSE20123 AUP1 550 10 2 18
GSE43470 AUP1 550 4 0 39
GSE46452 AUP1 550 2 3 54
GSE47630 AUP1 550 7 0 33
GSE54993 AUP1 550 0 6 64
GSE54994 AUP1 550 10 0 43
GSE60625 AUP1 550 0 3 8
GSE74703 AUP1 550 4 0 32
GSE74704 AUP1 550 8 0 12
TCGA AUP1 550 37 2 57

Total number of gains: 91; Total number of losses: 18; Total Number of normals: 379.  

 

Somatic mutations of AUP1:

 

Generating mutation plots.

 

Highly correlated genes for AUP1:

 

Showing top 20/1520 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
AUP1SLC39A30.780036303
AUP1CDCA20.777672404
AUP1ZBTB90.753789303
AUP1ZNF6280.740617303
AUP1DNTTIP10.737782404
AUP1YWHAG0.735543505
AUP1RTKN0.731487908
AUP1KCNS20.730457303
AUP1DNAJB110.728941606
AUP1C16orf740.728077707
AUP1EBNA1BP20.717723303
AUP1EME10.713827504
AUP1TOP2A0.710502909
AUP1TRIM470.704244303
AUP1ITGB40.70359911010
AUP1SLC19A10.70186303
AUP1PSMG30.701657707
AUP1CDH240.701639303
AUP1FMNL20.698868707
AUP1POLR1B0.698646505

For details and further investigation, click here