| Full name: SLC9A3 regulator 2 | Alias Symbol: SIP-1|TKA-1|NHERF-2|E3KARP | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 9351 | HGNC ID: HGNC:11076 | Ensembl Gene: ENSG00000065054 | OMIM ID: 606553 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC9A3R2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC9A3R2 | 9351 | 209830_s_at | -0.0509 | 0.8628 | |
| GSE20347 | SLC9A3R2 | 9351 | 209830_s_at | -0.0484 | 0.3427 | |
| GSE23400 | SLC9A3R2 | 9351 | 209830_s_at | -0.0833 | 0.0013 | |
| GSE26886 | SLC9A3R2 | 9351 | 209830_s_at | 0.0589 | 0.5997 | |
| GSE29001 | SLC9A3R2 | 9351 | 209830_s_at | -0.0731 | 0.3664 | |
| GSE38129 | SLC9A3R2 | 9351 | 209830_s_at | -0.0644 | 0.4095 | |
| GSE45670 | SLC9A3R2 | 9351 | 209830_s_at | -0.0156 | 0.8687 | |
| GSE53622 | SLC9A3R2 | 9351 | 70394 | 0.1636 | 0.0048 | |
| GSE53624 | SLC9A3R2 | 9351 | 70394 | -0.0124 | 0.8593 | |
| GSE63941 | SLC9A3R2 | 9351 | 209830_s_at | -0.0262 | 0.9016 | |
| GSE77861 | SLC9A3R2 | 9351 | 209830_s_at | -0.0636 | 0.7049 | |
| GSE97050 | SLC9A3R2 | 9351 | A_24_P364838 | 0.2613 | 0.2581 | |
| SRP007169 | SLC9A3R2 | 9351 | RNAseq | -0.7138 | 0.2307 | |
| SRP008496 | SLC9A3R2 | 9351 | RNAseq | -0.2987 | 0.4806 | |
| SRP064894 | SLC9A3R2 | 9351 | RNAseq | -0.1358 | 0.7389 | |
| SRP133303 | SLC9A3R2 | 9351 | RNAseq | -0.4501 | 0.0233 | |
| SRP159526 | SLC9A3R2 | 9351 | RNAseq | 0.0946 | 0.7186 | |
| SRP193095 | SLC9A3R2 | 9351 | RNAseq | -0.1461 | 0.4924 | |
| SRP219564 | SLC9A3R2 | 9351 | RNAseq | -0.0697 | 0.9031 | |
| TCGA | SLC9A3R2 | 9351 | RNAseq | -0.3404 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SLC9A3R2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC9A3R2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC9A3R2 | 9351 | 5 | 5 | 20 | |
| GSE20123 | SLC9A3R2 | 9351 | 5 | 4 | 21 | |
| GSE43470 | SLC9A3R2 | 9351 | 4 | 7 | 32 | |
| GSE46452 | SLC9A3R2 | 9351 | 38 | 1 | 20 | |
| GSE47630 | SLC9A3R2 | 9351 | 13 | 6 | 21 | |
| GSE54993 | SLC9A3R2 | 9351 | 3 | 5 | 62 | |
| GSE54994 | SLC9A3R2 | 9351 | 5 | 9 | 39 | |
| GSE60625 | SLC9A3R2 | 9351 | 4 | 0 | 7 | |
| GSE74703 | SLC9A3R2 | 9351 | 4 | 5 | 27 | |
| GSE74704 | SLC9A3R2 | 9351 | 3 | 2 | 15 | |
| TCGA | SLC9A3R2 | 9351 | 19 | 14 | 63 |
Total number of gains: 103; Total number of losses: 58; Total Number of normals: 327.
Somatic mutations of SLC9A3R2:
Generating mutation plots.
Highly correlated genes for SLC9A3R2:
Showing top 20/196 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC9A3R2 | PDE4A | 0.771764 | 3 | 0 | 3 |
| SLC9A3R2 | MYPOP | 0.736283 | 3 | 0 | 3 |
| SLC9A3R2 | ICAM2 | 0.709096 | 3 | 0 | 3 |
| SLC9A3R2 | SIK1 | 0.692322 | 3 | 0 | 3 |
| SLC9A3R2 | PLAC9 | 0.669304 | 3 | 0 | 3 |
| SLC9A3R2 | LRRC4B | 0.660617 | 3 | 0 | 3 |
| SLC9A3R2 | GPC6 | 0.652843 | 3 | 0 | 3 |
| SLC9A3R2 | ZDHHC1 | 0.645226 | 3 | 0 | 3 |
| SLC9A3R2 | FBLN5 | 0.633144 | 3 | 0 | 3 |
| SLC9A3R2 | HTRA3 | 0.623852 | 3 | 0 | 3 |
| SLC9A3R2 | ACKR4 | 0.623753 | 3 | 0 | 3 |
| SLC9A3R2 | DENND3 | 0.621438 | 3 | 0 | 3 |
| SLC9A3R2 | PNMA2 | 0.619807 | 4 | 0 | 3 |
| SLC9A3R2 | MXRA8 | 0.61748 | 4 | 0 | 3 |
| SLC9A3R2 | TRAK1 | 0.617338 | 3 | 0 | 3 |
| SLC9A3R2 | SARDH | 0.617224 | 6 | 0 | 4 |
| SLC9A3R2 | SPI1 | 0.616335 | 4 | 0 | 4 |
| SLC9A3R2 | DIXDC1 | 0.61633 | 3 | 0 | 3 |
| SLC9A3R2 | TRIM31 | 0.615718 | 4 | 0 | 3 |
| SLC9A3R2 | RPRML | 0.614831 | 4 | 0 | 3 |
For details and further investigation, click here
