PRDM14

 

Full name: PR/SET domain 14 Alias Symbol: 
Type: protein-coding gene Cytoband: 8q13.3
Entrez ID: 63978 HGNC ID: HGNC:14001 Ensembl Gene: ENSG00000147596 OMIM ID: 611781
Drug and gene relationship at DGIdb

 

Expression of PRDM14:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PRDM14 63978 220714_at -0.0688 0.8842
GSE20347 PRDM14 63978 220714_at -0.0694 0.5479
GSE23400 PRDM14 63978 220714_at -0.1595 0.0002
GSE26886 PRDM14 63978 220714_at 0.0912 0.5138
GSE29001 PRDM14 63978 220714_at -0.1652 0.4336
GSE38129 PRDM14 63978 220714_at -0.2195 0.1240
GSE45670 PRDM14 63978 220714_at 0.1200 0.3097
GSE53622 PRDM14 63978 88552 0.0958 0.3807
GSE53624 PRDM14 63978 88552 0.4854 0.0000
GSE63941 PRDM14 63978 220714_at -0.0691 0.7308
GSE77861 PRDM14 63978 220714_at -0.1838 0.0823
SRP133303 PRDM14 63978 RNAseq 0.1794 0.3345
SRP193095 PRDM14 63978 RNAseq 0.1092 0.5115
TCGA PRDM14 63978 RNAseq 1.1557 0.4849

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by PRDM14 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of PRDM14:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PRDM14 63978 15 1 14
GSE20123 PRDM14 63978 16 1 13
GSE43470 PRDM14 63978 18 1 24
GSE46452 PRDM14 63978 20 2 37
GSE47630 PRDM14 63978 23 1 16
GSE54993 PRDM14 63978 0 19 51
GSE54994 PRDM14 63978 28 1 24
GSE60625 PRDM14 63978 0 4 7
GSE74703 PRDM14 63978 15 1 20
GSE74704 PRDM14 63978 11 0 9
TCGA PRDM14 63978 50 2 44

Total number of gains: 196; Total number of losses: 33; Total Number of normals: 259.  


 

Somatic mutations of PRDM14:

 

Generating mutation plots.

 

Highly correlated genes for PRDM14:

 

Showing top 20/787 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PRDM14KIAA16140.724455606
PRDM14TUB0.711097404
PRDM14BTNL20.700387505
PRDM14SLC10A10.699229606
PRDM14SLC17A90.696716303
PRDM14MROH90.693673303
PRDM14KRT760.689223606
PRDM14RECK0.678325303
PRDM14ATG100.673804404
PRDM14TSSK60.673459303
PRDM14ZBTB7C0.669275303
PRDM14PHF70.664709605
PRDM14PRLR0.664502605
PRDM14KLHDC8A0.664473403
PRDM14GDF50.658688504
PRDM14THRA0.658666303
PRDM14FOXN3-AS20.657698504
PRDM14GATA10.656967504
PRDM14NPHS20.653893606
PRDM14DCD0.653766303

For details and further investigation, click here