| Full name: Rho family GTPase 1 | Alias Symbol: Rho6|ARHS|RHOS | ||
| Type: protein-coding gene | Cytoband: 12q13.12 | ||
| Entrez ID: 27289 | HGNC ID: HGNC:18314 | Ensembl Gene: ENSG00000172602 | OMIM ID: 609038 |
| Drug and gene relationship at DGIdb | |||
RND1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04360 | Axon guidance |
Expression of RND1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RND1 | 27289 | 210056_at | -0.6615 | 0.5018 | |
| GSE20347 | RND1 | 27289 | 210056_at | -0.1127 | 0.1228 | |
| GSE23400 | RND1 | 27289 | 210056_at | -0.2173 | 0.0000 | |
| GSE26886 | RND1 | 27289 | 210056_at | -0.2434 | 0.3476 | |
| GSE29001 | RND1 | 27289 | 210056_at | -0.3990 | 0.0594 | |
| GSE38129 | RND1 | 27289 | 210056_at | -0.4437 | 0.0207 | |
| GSE45670 | RND1 | 27289 | 210056_at | 0.4172 | 0.2388 | |
| GSE53622 | RND1 | 27289 | 58242 | 0.0731 | 0.2318 | |
| GSE53624 | RND1 | 27289 | 58242 | -0.2515 | 0.0012 | |
| GSE63941 | RND1 | 27289 | 210056_at | 0.4486 | 0.2518 | |
| GSE77861 | RND1 | 27289 | 210056_at | -0.1486 | 0.1624 | |
| GSE97050 | RND1 | 27289 | A_23_P53370 | 0.1969 | 0.7675 | |
| SRP064894 | RND1 | 27289 | RNAseq | -1.5083 | 0.0000 | |
| SRP133303 | RND1 | 27289 | RNAseq | -0.7577 | 0.1661 | |
| SRP159526 | RND1 | 27289 | RNAseq | -1.2325 | 0.0391 | |
| SRP219564 | RND1 | 27289 | RNAseq | -0.8338 | 0.4148 | |
| TCGA | RND1 | 27289 | RNAseq | -0.8317 | 0.0049 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by RND1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RND1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RND1 | 27289 | 6 | 1 | 23 | |
| GSE20123 | RND1 | 27289 | 6 | 1 | 23 | |
| GSE43470 | RND1 | 27289 | 4 | 1 | 38 | |
| GSE46452 | RND1 | 27289 | 8 | 1 | 50 | |
| GSE47630 | RND1 | 27289 | 11 | 2 | 27 | |
| GSE54993 | RND1 | 27289 | 0 | 5 | 65 | |
| GSE54994 | RND1 | 27289 | 6 | 1 | 46 | |
| GSE60625 | RND1 | 27289 | 0 | 0 | 11 | |
| GSE74703 | RND1 | 27289 | 4 | 1 | 31 | |
| GSE74704 | RND1 | 27289 | 4 | 1 | 15 | |
| TCGA | RND1 | 27289 | 16 | 12 | 68 |
Total number of gains: 65; Total number of losses: 26; Total Number of normals: 397.
Somatic mutations of RND1:
Generating mutation plots.
Highly correlated genes for RND1:
Showing top 20/85 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RND1 | IL6 | 0.815386 | 3 | 0 | 3 |
| RND1 | SOCS3 | 0.760444 | 3 | 0 | 3 |
| RND1 | KIAA0895L | 0.717326 | 3 | 0 | 3 |
| RND1 | MBD5 | 0.707424 | 3 | 0 | 3 |
| RND1 | SOX17 | 0.680397 | 4 | 0 | 3 |
| RND1 | LYVE1 | 0.679572 | 3 | 0 | 3 |
| RND1 | SELE | 0.677602 | 4 | 0 | 4 |
| RND1 | WSB1 | 0.66365 | 4 | 0 | 3 |
| RND1 | C16orf86 | 0.66033 | 3 | 0 | 3 |
| RND1 | HYDIN | 0.65631 | 3 | 0 | 3 |
| RND1 | RNF148 | 0.65471 | 3 | 0 | 3 |
| RND1 | KCNRG | 0.653598 | 3 | 0 | 3 |
| RND1 | CIDEC | 0.639444 | 3 | 0 | 3 |
| RND1 | NANOS3 | 0.637066 | 4 | 0 | 4 |
| RND1 | NR4A1 | 0.631201 | 5 | 0 | 3 |
| RND1 | MYO1E | 0.628076 | 3 | 0 | 3 |
| RND1 | NLRP12 | 0.624213 | 3 | 0 | 3 |
| RND1 | PRKAB1 | 0.624088 | 3 | 0 | 3 |
| RND1 | NUMBL | 0.607554 | 3 | 0 | 3 |
| RND1 | PPP1R15A | 0.59832 | 7 | 0 | 5 |
For details and further investigation, click here
