| Full name: tetratricopeptide repeat domain 38 | Alias Symbol: FLJ20699 | ||
| Type: protein-coding gene | Cytoband: 22q13.31 | ||
| Entrez ID: 55020 | HGNC ID: HGNC:26082 | Ensembl Gene: ENSG00000075234 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TTC38:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TTC38 | 55020 | 218272_at | 0.3220 | 0.2189 | |
| GSE20347 | TTC38 | 55020 | 216434_at | -0.0904 | 0.3442 | |
| GSE23400 | TTC38 | 55020 | 218272_at | -0.0212 | 0.5919 | |
| GSE26886 | TTC38 | 55020 | 218272_at | 0.1108 | 0.6394 | |
| GSE29001 | TTC38 | 55020 | 218272_at | -0.1191 | 0.5862 | |
| GSE38129 | TTC38 | 55020 | 218272_at | -0.1199 | 0.2420 | |
| GSE45670 | TTC38 | 55020 | 218272_at | 0.0831 | 0.3856 | |
| GSE53622 | TTC38 | 55020 | 72321 | -0.2205 | 0.0431 | |
| GSE53624 | TTC38 | 55020 | 72321 | -0.0473 | 0.6537 | |
| GSE63941 | TTC38 | 55020 | 218272_at | -0.3682 | 0.3572 | |
| GSE77861 | TTC38 | 55020 | 218272_at | 0.1426 | 0.6012 | |
| GSE97050 | TTC38 | 55020 | A_24_P156388 | 0.0954 | 0.6609 | |
| SRP007169 | TTC38 | 55020 | RNAseq | -0.4454 | 0.2887 | |
| SRP008496 | TTC38 | 55020 | RNAseq | -0.7455 | 0.0089 | |
| SRP064894 | TTC38 | 55020 | RNAseq | 0.4476 | 0.0200 | |
| SRP133303 | TTC38 | 55020 | RNAseq | -0.1903 | 0.3262 | |
| SRP159526 | TTC38 | 55020 | RNAseq | -0.0242 | 0.9288 | |
| SRP193095 | TTC38 | 55020 | RNAseq | -0.2132 | 0.3513 | |
| SRP219564 | TTC38 | 55020 | RNAseq | 0.4329 | 0.0733 | |
| TCGA | TTC38 | 55020 | RNAseq | -0.3730 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TTC38 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TTC38:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TTC38 | 55020 | 5 | 6 | 19 | |
| GSE20123 | TTC38 | 55020 | 4 | 5 | 21 | |
| GSE43470 | TTC38 | 55020 | 2 | 6 | 35 | |
| GSE46452 | TTC38 | 55020 | 31 | 2 | 26 | |
| GSE47630 | TTC38 | 55020 | 9 | 4 | 27 | |
| GSE54993 | TTC38 | 55020 | 3 | 6 | 61 | |
| GSE54994 | TTC38 | 55020 | 11 | 7 | 35 | |
| GSE60625 | TTC38 | 55020 | 5 | 0 | 6 | |
| GSE74703 | TTC38 | 55020 | 2 | 4 | 30 | |
| GSE74704 | TTC38 | 55020 | 2 | 3 | 15 | |
| TCGA | TTC38 | 55020 | 27 | 15 | 54 |
Total number of gains: 101; Total number of losses: 58; Total Number of normals: 329.
Somatic mutations of TTC38:
Generating mutation plots.
Highly correlated genes for TTC38:
Showing top 20/125 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TTC38 | APOE | 0.736544 | 3 | 0 | 3 |
| TTC38 | HYOU1 | 0.701338 | 3 | 0 | 3 |
| TTC38 | EXOSC5 | 0.69617 | 4 | 0 | 4 |
| TTC38 | RASAL3 | 0.688796 | 3 | 0 | 3 |
| TTC38 | FXR2 | 0.683071 | 4 | 0 | 4 |
| TTC38 | GNAO1 | 0.643478 | 4 | 0 | 4 |
| TTC38 | CNTROB | 0.630839 | 3 | 0 | 3 |
| TTC38 | HOXD8 | 0.630738 | 4 | 0 | 3 |
| TTC38 | CDK18 | 0.630526 | 4 | 0 | 3 |
| TTC38 | R3HDM4 | 0.63001 | 3 | 0 | 3 |
| TTC38 | GPAA1 | 0.629042 | 4 | 0 | 4 |
| TTC38 | CD19 | 0.627723 | 4 | 0 | 3 |
| TTC38 | SH3PXD2B | 0.624556 | 3 | 0 | 3 |
| TTC38 | SPIRE2 | 0.623932 | 3 | 0 | 3 |
| TTC38 | VPS28 | 0.613881 | 3 | 0 | 3 |
| TTC38 | UBR4 | 0.612266 | 3 | 0 | 3 |
| TTC38 | FBXO2 | 0.612049 | 3 | 0 | 3 |
| TTC38 | NRGN | 0.608363 | 3 | 0 | 3 |
| TTC38 | TRIB2 | 0.607059 | 3 | 0 | 3 |
| TTC38 | SRC | 0.606732 | 3 | 0 | 3 |
For details and further investigation, click here
